Laurie D. DeLeve – författare

This field has shown tremendous growth in recent years, primarily due to the recognition that drug-induced liver disease is the most common cause of liver failure and one of the major contributors to the withdrawal of drugs developed by the pharmaceutical industry. Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more. Written by highly respected authorities, this new edition is an updated and definitive reference for clinicians and scientists in academia, the pharmaceutical industry and government settings. This book contains 4 new chapters on key topics in the area and provides a current and extensive review of the latest developments concerning the toxicology, pharmacology, genetics and immunology of drug-induced liver disease.

A multi-authored reference work written by leading clinical, academic and industry experts in drug-induced liver disease Contains four new chapters on key areas in the field, including one on worldwide drug-induced liver injury networks Each chapter has been updated to address the latest research and findings in the field and 16 new chapter authors have been added to this new edition Includes coverage of the basic, clinical and practical aspects of drug-induced liver disease to provide the single most comprehensive reference on the subject

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines. This book supplies an in-depth discussion of drug-induced hepatoxicology, covering mechanisms, histopathology, management, risk factors, and patterns of drug and toxin-induced disease. It includes contributions international experts.

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines. This book supplies an in-depth discussion of drug-induced hepatoxicology, covering mechanisms, histopathology, management, risk factors, and patterns of drug and toxin-induced disease. It includes contributions international experts.

Vascular Liver Disease: Mechanisms and Management covers all of the disease entities that stem from abnormalities that affect the hepatic vasculature. This multi-authored text includes the mechanisms and management of intrahepatic vascular disease, including the most common cause of vascular disease of the liver, cirrhosis. Other less common diseases of the liver vasculature are also covered such as sinusoidal obstruction syndrome (previously known as veno-occlusive disease), portal vein thrombosis, the Budd-Chiari syndrome and congenital vascular malformations. These entities, although rare, are a challenge to physicians and physician scientists. Although many textbooks have been written on the consequences of cirrhosis on the liver vasculature, this is the only volume that focuses on the liver vasculature as a separate entity, providing an innovative approach to liver disease management. Vascular Liver Disease: Mechanisms and Management will be of great value to clinical investigators and basic scientists interested in the liver circulation as well as clinical gastroenterologists and hepatologists, hepatobiliary surgeons and transplant surgeons, and to interventional radiologists with a particular interest in the liver.