Luana Colloca – författare

The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers' knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain.

Review for Placebo and Pain:"This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues.�--Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School

Contains historical aspects of the placebo effect Discusses biological and psychological mechanisms of placebo analgesic responses Reviews implications of the placebo effect for clinical research and pain management Includes methodological and ethical aspects of the placebo effect

The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers'' knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain.Review for Placebo and Pain:"This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues.--Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School- Contains historical aspects of the placebo effect- Discusses biological and psychological mechanisms of placebo analgesic responses- Reviews implications of the placebo effect for clinical research and pain management- Includes methodological and ethical aspects of the placebo effect

Placebo Effects Through the Lens of Translational Research is an Open Access book integrating current knowledge on placebo research in healthcare to develop comprehensive and adequate strategies for better symptom management and treatment responses. This edited collection features the work of experts in placebo studies, including women, people of color, and international scholars, helping to diversify the existing scholarship in the field. It presents the latest research findings while also considers theoretical aspects of placebo. Together, the chapters in this volume help bridge the gulf between research and ideas in placebo studies and their day-to-day application in clinical practice in order to improve healthcare and health outcomes.Responses to placebos can be as significant as the observed results of active treatments in Phase II/III randomized clinical trials. These results have led to a stagnant era in new drug development since the effect of these potential therapeutics have similar, measured effects as the placebos used in the same trials. This book sheds light on translational aspects related to placebo and drug treatment methods. It also evaluates the clinical implications of a much-needed integration of pharmacological and nonpharmacological treatments in healthcare.Placebo Effects Through the Lens of Translational Research concludes with a discussion of the most innovative developments in placebo research, which will be of interest to a wide readership, including clinicians, senior scientists, trainees, and patients. In a single volume, Placebo Effects Through the Lens of Translational Research provides readers with an overview of current perspectives on placebo research and translational applications.

Placebo Effects Through the Lens of Translational Research is an Open Access book integrating current knowledge on placebo research in healthcare to develop comprehensive and adequate strategies for better symptom management and treatment responses. This edited collection features the work of experts in placebo studies, including women, people of color, and international scholars, helping to diversify the existing scholarship in the field. It presents the latest research findings while also considers theoretical aspects of placebo. Together, the chapters in this volume help bridge the gulf between research and ideas in placebo studies and their day-to-day application in clinical practice in order to improve healthcare and health outcomes.Responses to placebos can be as significant as the observed results of active treatments in Phase II/III randomized clinical trials. These results have led to a stagnant era in new drug development since the effect of these potential therapeutics have similar, measured effects as the placebos used in the same trials. This book sheds light on translational aspects related to placebo and drug treatment methods. It also evaluates the clinical implications of a much-needed integration of pharmacological and nonpharmacological treatments in healthcare.Placebo Effects Through the Lens of Translational Research concludes with a discussion of the most innovative developments in placebo research, which will be of interest to a wide readership, including clinicians, senior scientists, trainees, and patients. In a single volume, Placebo Effects Through the Lens of Translational Research provides readers with an overview of current perspectives on placebo research and translational applications.

The placebo effect is a fascinating but elusive phenomena. Although no standard definition of the placebo effect exists, it is generally understood as consisting of responses of individuals to the psychosocial context of medical treatments or clinical encounters, as distinct from specific physiological effects of medical interventions. The Placebo is the first book to compile a selection of classic and contemporary published articles on the topic. Systematic investigation of the placebo effect emerged in the 1950s in response to the development of randomized controlled clinical trials that used "inert" placebo interventions as a pivotal element of scientific evaluation of novel drugs. In recent years, scientific and scholarly investigation of the placebo effect has increased dramatically, reflecting a growing interest in the connection between mind and body with respect to health, the development of brain imaging techniques, dissatisfaction with the reductionist and technological orientation of biomedicine, and growing attention to the use of complementary and alternative medical treatments.The Placebo is organized into three sections: the nature and significance of the placebo effect, experimental studies of the placebo effect, and ethical issues of placebos in research and in clinical practice. This comprehensive sourcebook will be invaluable to investigators and scholars alike.