Luca Saba – författare

Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of the neurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-array profiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. This book is an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart.In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology.Given these exciting developments, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain is a timely addition to the growing body of literature in the field. Covering MRI from fundamentals to practice, this comprehensive book:Discusses the clinical benefits of diagnosing human pathologies using MRIExplains the physical principles of MRI and how to use the technique correctlyHighlights each organ’s anatomy and pathological processes with high-quality imagesExamines the protocols and potentialities of advanced MRI scanners such as 7 T systemsIncludes extensive references at the end of each chapter to enhance further studyThus, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart.In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology.Given these exciting developments, the Magnetic Resonance Imaging Handbook: Imaging of the Pelvis, Musculoskeletal System, and Special Applications to CAD is a timely addition to the growing body of literature in the field. Offering comprehensive coverage of cutting-edge imaging modalities, this book: Discusses MRI of the urinary system, pelvis, spine, soft tissues, lymphatics, and brainExplains how MRI can be used in fetal, pediatric, forensic, postmortem, and computer-aided diagnostic (CAD) applicationsHighlights each organ’s anatomy and pathological processes with high-quality imagesExamines the protocols and potentialities of advanced MRI scanners such as 7 T systemsIncludes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook: Imaging of the Pelvis, Musculoskeletal System, and Special Applications to CAD provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart.In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology.Given these exciting developments, the Magnetic Resonance Imaging Handbook: Imaging of the Cardiovascular System, Thorax, and Abdomen is a timely addition to the growing body of literature in the field. Offering comprehensive coverage of cutting-edge imaging modalities, this book: Discusses MRI of the heart, blood vessels, lungs, breasts, diaphragm, liver, gallbladder, spleen, pancreas, adrenal glands, and gastrointestinal tractExplains how MRI can be used in vascular, posttraumatic, postsurgical, and computer-aided diagnostic (CAD) applicationsHighlights each organ’s anatomy and pathological processes with high-quality imagesExamines the protocols and potentialities of advanced MRI scanners such as 7 T systemsIncludes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook: Imaging of the Cardiovascular System, Thorax, and Abdomen provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

COVID-19 Radiological Lung Imaging: A Classic Artificial Intelligence Framework introduces modern AI technologies for early detection of COVID-19 disease to assist in saving patient lives and safeguarding frontline workers. With a strong focus on Deep Learning, the book examines specific detection and classification techniques in lung X-ray imaging, computed tomography lung imaging, deep learning on edge devises and bias measurements, deep learning for cloud and explainable AI for validation, and discusses the medical impact and AI implications for COVID-19 in lung pathologies. It is therefore an ideal reference for researchers and clinicians working in radiology and pulmonary medicine to learn the modern AI technologies in COVID-19 paradigms for implementation.

Colorectal Imaging: From Basic to Advanced Concepts provides an exhaustive overview of today’s basic and advanced principles of colorectal imaging, focusing not only on oncologic but also inflammatory, infective, and ischemic pathologies and complications. The book reviews basic colorectal cancer information, examines imaging techniques and analysis, and concludes with a review of non-neoplastic pathologies. It is a useful resource for scientists, physicians, and medical students in the discipline of radiology, highlighting the critical role of contemporary imaging in guiding clinical and surgical approaches and providing the knowledge needed to confidently choose the most appropriate imaging examination.Presents an up-to-date overview of current approaches in colorectal imaging, particularly in oncologic stagingCovers applications of radiomics and artificial intelligence in colorectal imagingDistinguishes between diagnosis neoplastic and non-neoplastic colorectal pathologies

Multiple Faces of Takotsubo Syndrome: Clinical Presentaions, Mechanisms and Advanced Diagnostic Insights offers a thorough and up-to-date review of Takotsubo syndrome and the role of advanced imaging techniques in improving diagnosis, monitoring, and management of this complex cardiac condition. With rapid advancements in understanding Takotsubo syndrome and imaging technologies, there is a critical need for a text that integrates the latest research, clinical insights, and cutting-edge imaging methods, providing a holistic resource for those managing this evolving condition. The book is structured into six detailed sections. It begins with an introduction to Takotsubo syndrome, covering its historical background, prevalence, and key clinical characteristics. Subsequent chapters delve into epidemiology, risk factors, and psychological aspects, including the impact of COVID-19 and other viral infections. The clinical manifestations, management, prevention, and treatments are thoroughly discussed, along with complications and prognosis. The basic science section explores the pathophysiological mechanisms, the heart-brain axis, and multi-organ involvement. A significant focus throughout is placed on invasive and non-invasive imaging modalities, including angiography, echocardiography, cardiac MRI, computed tomography, and nuclear imaging. Future directions highlight emerging biomarkers and imaging techniques for personalized medicine, and real-world case studies provide practical insights for clinicians. Multiple Faces of Takotsubo Syndrome: Clinical Presentaions, Mechanisms and Advanced Diagnostic Insights offers invaluable benefits to scientists, researchers, and clinicians alike. The special focus on cutting-edge imaging technologies enables a deeper understanding of disease mechanisms and new avenues for innovation. The book connects foundational research with real-world clinical applications, offering practical guidance for managing patients with Takotsubo syndrome. The unique emphasis on advanced imaging modalities enhances diagnosis, management, and prognosis, making this text an essential resource for those dedicated to advancing the care and treatment of Takotsubo syndrome.Integrates advanced imaging techniques for improved diagnosis and management of Takotsubo syndromeHighlights the latest developments in imaging technologies and their clinical applicationsOffers practical guidance on using cardiac MRI and echocardiography for accurate diagnosisExplores innovative approaches combining imaging and biomarkers for personalized treatmentIncludes full-page multi-panel images aimed at enhancing understanding and facilitating the comparison of complex data and anatomical structures

Neurobiology and Artificial Intelligence: Medical, Social, and Ethical Implicationsexplores the dynamic intersection of neurobiology and artificial intelligence (AI),investigating the scientific, philosophical, and ethical implications of these rapidlyevolving fields. By blending cutting-edge research with thought-provoking discussions,this book aims to make complex topics accessible to an interdisciplinary audience,from researchers and upper graduate students eager to understand how AI andneuroscience shape our understanding of intelligence, creativity, learning, and thehuman condition.Offers clear explanations of scientific and technical conceptsEmphasizes the societal and moral challenges posed by advancements in AI and neuroscienceExplores how neurobiology and AI influence each other and their broader impact on medicine, creativity, and human cognition

This book includes detailed coverage of MRI clinical applications of the head, neck and brain pathologies. Main topics are treated by leading authors in the head and neck field with outstanding quality images providing an easy usable and exhaustive text both for residents and skilled physicians.Image Principles, Neck, and the Brain, Second Edition confirms itself as a quick reference guide for all users who wish to find an exhaustive and precise coverage of key facts on head and neck MRI imaging exposed in easy to read chapters including the most updated information about the latest applications of MRI in the diagnosis of head, neck and brain main diseases. This book discusses the clinical benefits of diagnosing human pathologies using MRI, and it explains the physical principles of MRI and how to use the technique correctly. Building on the previous edition, this book also includes new chapters on Magnetic Resonance Angiography (MRA), MR spectroscopy, AI algorithms application for the MRI quality of image improvement, viral diseases of the brain and COVID. The book is part of the Magnetic Resonance Imaging, Second Edition set.This book is intended for students, radiologists and imaging specialists looking for a state-of-the-art reference in MRI.

This volume provides a comprehensive overview of the countless MRI applications in the evaluation and diagnosis of the musculoskeletal system, introducing a brand new set of chapters on CAD applications.Imaging of Musculoskeletal System and Special Applications to CAD, Second Edition, includes revised contents and high-quality images in an easy- to- understand resource to perform and interpret quality musculoskeletal MRI. From spine pathologies to muscles and soft tissues, this guide helps the radiologist in acquiring the most reliable and complete imaging information to achieve the best diagnostic results. The authors also presents pediatric and fetal application of MRI and magnetic resonance guided focused ultrasound (MRgFUS) bones. Finally, this book also includes new chapters on, lower extremities (including knee – ankle – foot), shoulder and upper extremities (including elbow – wrist – hand), MR arthrography, and oncologic ablation technique MR based. It also includes CAD applications in the cardio-vascular,abdomen-GI system, gynecological system, breasts, and MSK. The book is part of the Magnetic Resonance Imaging, Second Edition set.This book is intended for students, radiologists and imaging specialists looking for a state-of-the-art reference in MRI.

This volume focuses on abdominal MRI techniques with a complete overview ranging from liver main pathologies to stomach, colon up to kidney and male and female pelvis diseases.Imaging of the Abdomen, GI System, Pelvis, and Urinary System provides a comprehensive guide to all main abdomen pathologies and MRI applications. As part of the Magnetic Resonance Imaging Handbook, Second Edition, this book is an ideal guide for clinical practice. The book discusses MRI of the urinary system, pelvis, spine, soft tissues, and lymphatics. The book also examines MR of the placenta and pregnant woman (excluding fetal). Thanks to the support of high-quality images the book provides complete coverage of magnetic resonance imaging of the abdomen and pelvis helping the radiologist to effectively interpret findings under the guidance of the most relevant experts in the field. The expanded edition has also been enriched with new chapters on esophageal MRI imaging and extraperitoneal diseases. The book is part of the Magnetic Resonance Imaging, Second Edition set.This book is intended for students, radiologists and imaging specialists looking for a state-of-the-art reference on MRI.

This book includes coverage of Cardiovascular Magnetic Resonance (CMR) applications from cardiac physiology to the interpretation and diagnosis of cardiovascular and chest diseases providing up-to-date information on CMR uses, in cardiovascular care and thoracic pathologies from basic principles to the latest imaging techniques.As part of the Magnetic Resonance Imaging Handbook, Second Edition, this book is an ideal guide for clinical practice. It shows the most updated state-of-the-art coverage of CMR technologies and guidelines from basic principles to the latest imaging techniques. A wide section is dedicated to MRI imaging of thoracic structures with a focus on the evaluation of the lungs and its main diseases. This book discusses MRI of the heart, blood vessels, lungs, breasts, diaphragm, liver, gallbladder, spleen, pancreas, adrenal glands, and gastrointestinal tract. The new edition has been revised throughout with an extensive update and introduction of new chapters focusing on CMR techniques and COVID-19 related findings. It also includes new chapters focusing on CMR techniques, valvopathies, myocarditis, inflammatory cardiomyopathies, cardiac masses, pseudomassess, tumors, pulmonary embolism, and pulmonary hypertension. The book is part of the Magnetic Resonance Imaging, Second Edition set.This book is intended for students, radiologists and imaging specialists looking for a state-of-the-art reference in MRI.

Developments in CT technology during the last 20 years have impressively improved its diagnostic potentialities. Part of a two-volume set that covers all aspects of CT imaging, Multi-Detector CT Imaging: Abdomen, Pelvis, and CAD Applications contains easily searchable clinical specialty chapters that provide specific information without need of an index. The coverage goes far beyond just a "how-to" or an encyclopedia of findings, however. The authors have uniformly put techniques, clinical findings, pathologic disease presentations, and clinical implications in practical perspective. It is no wonder that with the critical role CT plays and the rapid innovations in computer technology that advances in the capabilities and complexity of CT imaging continue to evolve. While information about these developments may be scattered about in journals and other resources, this two-volume set provides an authoritative, up-to-date, and educational reference that covets the entire spectrum of CT.

Developments in CT technology during the last 20 years have impressively improved its diagnostic potentialities. Part of a two-volume set that covers all aspects of CT imaging, Multi-Detector CT Imaging: Principles, Head, Neck, and Vascular Systems contains easily searchable clinical specialty chapters that provide specific information without need of an index. The coverage goes far beyond just a "how-to" or an encyclopedia of findings, however. The authors have uniformly put techniques, clinical findings, pathologic disease presentations, and clinical implications of imaging findings in practical perspective. This Volume Features: Discusses technical principles, CT perfusion, contrast media, postprocessing and clinical applications, and radiation doseCovers imaging of the neck and brain, including paranasal sinuses and the ear, brain tumors, neurodegenerative diseases, CNS infection, and head traumaExamines how to use CT data for planning cardiovascular proceduresIncludes coverage of pathologies of the pericardium and CT venographyPresents information on clinical applications in lung disease With the critical role CT plays and the rapid innovations in computer technology, it is no wonder that advances in the capabilities and complexity of CT imaging continue to evolve. While information about these developments may be scattered about in journals and other resources, this two-volume set provides an authoritative, up-to-date, and educational reference that covets the entire spectrum of CT.

Preoperative imaging is increasingly being adopted for preoperative planning in plastic and reconstructive surgery. Accurate preoperative analysis can reduce the length of operations and maximize surgical design and dissection techniques. Imaging for Plastic Surgery covers the techniques, applications, and potentialities of medical imaging technology in plastic and reconstructive surgery. Presenting state-of-the-art research on evolving imaging modalities, this cutting-edge text:Provides a practical introduction to imaging modalities that can be used during preoperative planningAddresses imaging principles of the face, head, neck, breast, trunk, and extremitiesIdentifies the strengths and weaknesses of all available imaging modalitiesDemonstrates the added value of imaging in different clinical scenariosComprised of contributions from world-class experts in the field, Imaging for Plastic Surgery is an essential imaging resource for surgeons, radiologists, and patient care professionals.

Developments in CT technology during the last 20 years have impressively improved its diagnostic potentialities. Part of a two-volume set that covers all aspects of CT imaging, Multi-Detector CT Imaging: Principles, Head, Neck, and Vascular Systems contains easily searchable clinical specialty chapters that provide specific information without need of an index. The coverage goes far beyond just a "how-to" or an encyclopedia of findings, however. The authors have uniformly put techniques, clinical findings, pathologic disease presentations, and clinical implications of imaging findings in practical perspective. This Volume Features: Discusses technical principles, CT perfusion, contrast media, postprocessing and clinical applications, and radiation doseCovers imaging of the neck and brain, including paranasal sinuses and the ear, brain tumors, neurodegenerative diseases, CNS infection, and head traumaExamines how to use CT data for planning cardiovascular proceduresIncludes coverage of pathologies of the pericardium and CT venographyPresents information on clinical applications in lung disease With the critical role CT plays and the rapid innovations in computer technology, it is no wonder that advances in the capabilities and complexity of CT imaging continue to evolve. While information about these developments may be scattered about in journals and other resources, this two-volume set provides an authoritative, up-to-date, and educational reference that covets the entire spectrum of CT.

Developments in CT technology during the last 20 years have impressively improved its diagnostic potentialities. Part of a two-volume set that covers all aspects of CT imaging, Multi-Detector CT Imaging: Abdomen, Pelvis, and CAD Applications contains easily searchable clinical specialty chapters that provide specific information without need of an index. The coverage goes far beyond just a "how-to" or an encyclopedia of findings, however. The authors have uniformly put techniques, clinical findings, pathologic disease presentations, and clinical implications in practical perspective. It is no wonder that with the critical role CT plays and the rapid innovations in computer technology that advances in the capabilities and complexity of CT imaging continue to evolve. While information about these developments may be scattered about in journals and other resources, this two-volume set provides an authoritative, up-to-date, and educational reference that covets the entire spectrum of CT.

Stroke is one of the leading causes of death in the world, resulting mostly from the sudden ruptures of atherosclerosis carotid plaques. Understanding why and how plaque develops and ruptures requires a multi-disciplinary approach such as radiology, biomedical engineering, medical physics, software engineering, hardware engineering, pathological and histological imaging. Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment presents a new dimension of understanding Atherosclerosis in 2D and 3D. This book presents work on plaque stress analysis in order to provide a general framework of computational modeling with atherosclerosis plaques. New algorithms based on 3D and 4D Ultrasound are presented to assess the atherosclerotic disease as well as very recent advances in plaque multimodality image fusion analysis.The goal of Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment is to fuse information obtained from different 3D medical image modalities, such as 3D US, CT and MRI, providing the medical doctor with some sort of augmented reality information about the atherosclerotic plaque in order to improve the accuracy of the diagnosis. Analysis of the plaque dynamics along the cardiac cycle is also a valuable indicator for plaque instability assessment and therefore for risk stratification. 4D Ultrasound, a sequence of 3D reconstructions of the region of interest along the time, can be used for this dynamic analysis. Multimodality Image Fusion is a very appealing approach because it puts together the best characteristics of each modality, such as, the high temporal resolution of US and the high spatial resolutions of MRI and CT.

The book covers novel strategies of state of the art in engineering and clinical analysis and approaches for analyzing abdominal imaging, including lung, mediastinum, pleura, liver, kidney and gallbladder. In the last years the imaging techniques have experienced a tremendous improvement in the diagnosis and characterization of the pathologies that affect abdominal organs. In particular, the introduction of extremely fast CT scanners and high Magnetic field MR Systems allow imaging with an exquisite level of detail the anatomy and pathology of liver, kidney, pancreas, gallbladder as well as lung and mediastinum. Moreover, thanks to the development of powerful computer hardware and advanced mathematical algorithms the quantitative and automated\semi automated diagnosis of the pathology is becoming a reality. Medical image analysis plays an essential role in the medical imaging field, including computer-aided diagnosis, organ/lesion segmentation, image registration, and image-guided therapy.  This book will cover all the imaging techniques, potential for applying such imaging clinically, and offer present and future applications as applied to the abdomen and thoracic imaging with the most world renowned scientists in these fields. The main aim of this book is to help advance scientific research within the broad field of abdominal imaging. This book focuses on major trends and challenges in this area, and it presents work aimed to identify new techniques and their use in medical imaging analysis for abdominal imaging. ​

​Diagnostic and pre-operative imaging has become increasingly adopted throughout the field of gynecology. In particular accurate preoperative analysis of ovarian pathology can improve the selection of the correct therapeutical approach, to reduce the length of operations, maximize surgical technique, and can ultimately improve a range of operative outcomes. New imaging modalities have advanced to the point of high resolution, three-dimensional analysis of tissue anatomy, composition and perfusion. Ultrasonography (US), Computed tomographic (CT) and magnetic resonance (MR) imaging have recently emerged as outstanding non-invasive techniques for the detection and characterization of ovarian pathology. In particular, US has probably now imposed itself as the “state-of-the-art” technique to explore the ovarian neoplasm, thanks the technical advancement like texture analysis (MGV) and 3D potentialities, although MR with new sequences like the diffusion-weighted imaging and greater magnetic fields (3 Tesla or more) may become leading methods in the future. The purpose of this book is to cover all the imaging techniques, potential for applying such imaging clinically, and to offer present and future applications as applied to ovarian pathology with the most world renowned scientists in these fields. The book is designed according to the pathological classification of the benign and malignant ovarian neoplasm by presenting for each pathology the clinical setting followed by the imaging approach. At the end of each chapter a “focus concept” paragraph will be presented with take-home point for the readers.

This book will comprise eight main sections: (1) The Basics, (2) Arteries of the Head and Neck (3) The basics of Intracranial Arteries (4) Diseases of the vessels (5) Stroke Imaging (6) Veins Imaging (7) Spine Imaging (8) Pediatrics.

Preoperative imaging is increasingly being adopted for preoperative planning in plastic and reconstructive surgery. Accurate preoperative analysis can reduce the length of operations and maximize surgical design and dissection techniques. Imaging for Plastic Surgery covers the techniques, applications, and potentialities of medical imaging technology in plastic and reconstructive surgery. Presenting state-of-the-art research on evolving imaging modalities, this cutting-edge text:Provides a practical introduction to imaging modalities that can be used during preoperative planningAddresses imaging principles of the face, head, neck, breast, trunk, and extremitiesIdentifies the strengths and weaknesses of all available imaging modalitiesDemonstrates the added value of imaging in different clinical scenariosComprised of contributions from world-class experts in the field, Imaging for Plastic Surgery is an essential imaging resource for surgeons, radiologists, and patient care professionals.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart.In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology.Given these exciting developments, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain is a timely addition to the growing body of literature in the field. Covering MRI from fundamentals to practice, this comprehensive book:Discusses the clinical benefits of diagnosing human pathologies using MRIExplains the physical principles of MRI and how to use the technique correctlyHighlights each organ’s anatomy and pathological processes with high-quality imagesExamines the protocols and potentialities of advanced MRI scanners such as 7 T systemsIncludes extensive references at the end of each chapter to enhance further studyThus, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.