Luigi Mansi – författare

This book covers all diagnostic and therapeutic aspects of neuro-oncological diseases. In the last decade, the management of brain tumors has been revolutionized following the new WHO classification and thanks to the introduction of molecular markers into the clinical routine. From an imaging point of view, the continuous technological developments and the implementation of various radiopharmaceuticals have paved the way to new clinical indications and has helped optimize patient management. In this context, a major breakthrough could derive from the introduction of radiomics and artificial intelligence in the diagnostic and therapeutic pathway. Not forgetting the emerging role of heavy-ion therapy as a complement to the innovative drugs and treatments adopted in medical oncology and radiation therapy.In the present book, all above-mentioned aspects are covered, starting with the novel standards for the WHO classification of brain tumors, to the up-to-date surgical techniques and advanced therapeutic approaches, passing through the currently available imaging modalities and ongoing developments embracing both radiology and nuclear medicine discipline. Imaging represents indeed the “trait d'union” for all the arguments described in the book; therefore, in most chapters there are dedicated sessions focused on the role of imaging in each specific context.The publication aims to fill the gap between the clinicians and all professionals directly involved in the management of patients with brain tumors and the newest scientific outreach. Moreover, thanks to the comprehensive insight into the latest technological developments, scientists and researchers interested in the topic will find the book a useful tool for future studies and perspective discoveries.

This book covers all diagnostic and therapeutic aspects of neuro-oncological diseases. In the last decade, the management of brain tumors has been revolutionized following the new WHO classification and thanks to the introduction of molecular markers into the clinical routine. From an imaging point of view, the continuous technological developments and the implementation of various radiopharmaceuticals have paved the way to new clinical indications and has helped optimize patient management. In this context, a major breakthrough could derive from the introduction of radiomics and artificial intelligence in the diagnostic and therapeutic pathway. Not forgetting the emerging role of heavy-ion therapy as a complement to the innovative drugs and treatments adopted in medical oncology and radiation therapy.In the present book, all above-mentioned aspects are covered, starting with the novel standards for the WHO classification of brain tumors, to the up-to-date surgical techniques and advanced therapeutic approaches, passing through the currently available imaging modalities and ongoing developments embracing both radiology and nuclear medicine discipline. Imaging represents indeed the “trait d'union” for all the arguments described in the book; therefore, in most chapters there are dedicated sessions focused on the role of imaging in each specific context.The publication aims to fill the gap between the clinicians and all professionals directly involved in the management of patients with brain tumors and the newest scientific outreach. Moreover, thanks to the comprehensive insight into the latest technological developments, scientists and researchers interested in the topic will find the book a useful tool for future studies and perspective discoveries.

This essential book, amid the rapid shift toward hybrid imaging, empowers radiographers, technologists and practitioners to build on solid fundamentals, strengthen patient care, and refine advanced techniques.Uniqueness: This book provides a comprehensive perspective on hybrid imaging and patient management, offering insights not only from physicians and radiographers but also from other key professionals, such as physicists, psychologists, and other interdisciplinary experts. Specifically tailored for radiographers—yet equally valuable for anyone seeking a deeper understanding of hybrid imaging technology and techniques—it fills a critical void in current educational resources.Structured Approach: Organized into eighteen chapters, the book offers a clear, methodical framework that starts with foundational concepts to introduce the reader to the subject and builds progressively toward more advanced topics, including specialized skills and patient-centered imaging practices. It is an excellent reference for professionals at any stage of their career, from beginners to experts.Target Audience: Designed for radiographers, students, residents, and practitioners exploring cutting-edge hybrid imaging technologies, this text bridges the gap between theoretical knowledge of instrumentation and its real-world application in both daily practice and patient care.Filling a gap: By comprehensively covering both hybrid imaging and patient management from a radiographer’s perspective, this textbook serves as an indispensable educational resource. It equips readers with the knowledge and skills needed to meet the growing demand for expertise and advanced, patient-tailored imaging in this dynamic field.

This book provides a comprehensive state-of-the-art review of pediatric nuclear medicine, encompassing both diagnostic and therapeutic applications. Detailed attention is paid to the role of FDG PET-CT within oncology, but a variety of other long-established or less frequently used diagnostic procedures are also covered. Each indication is critically discussed from a clinical perspective, with analysis of benefits and limitations and comparison against the information yield of alternative techniques. The coverage of therapy based on radiopharmaceuticals includes the most relevant current strategies, including those utilizing radioiodine, MIBG, or radiolabelled peptides. In addition, issues concerning the radiation risk of nuclear medicine procedures in children are addressed. All chapters have been written by international experts and include the most up-to-date scientific and clinical information.

Using SWOT analysis, this book examines in detail the strengths and weaknesses of the hybrid modalities PET-CT and PET-MRI for imaging of the central nervous system, comparing their merits and evaluating their advantages over the stand-alone modalities. The aim is to employ a truly systematic approach in order to define the potential clinical benefit of these modalities and to identify shortcomings, opportunities, and threats. Clinical application of the modalities is explored in a range of conditions, including dementia and related disorders, movement disorders, psychiatric disorders, cerebrovascular disease, infection/inflammation, brain tumors, and pediatric neurologic disorders. In addition, the basics of hybrid imaging are addressed, covering physics, instrumentation, data analysis and quantitation, radiopharmaceuticals, and contrast media. PET-CT and PET-MRI in Neurology, written by experts from Europe and the United States, will be essential reading for imaging specialists and of value for neurologists, psychiatrists, neurosurgeons, and pediatricians.

This book provides a comprehensive state-of-the-art review of pediatric nuclear medicine, encompassing both diagnostic and therapeutic applications. The coverage of therapy based on radiopharmaceuticals includes the most relevant current strategies, including those utilizing radioiodine, MIBG, or radiolabelled peptides.

Using SWOT analysis, this book examines in detail the strengths and weaknesses of the hybrid modalities PET-CT and PET-MRI for imaging of the central nervous system, comparing their merits and evaluating their advantages over the stand-alone modalities.

Although [18F]fluorodeoxyglucose (FDG) generally shows an excellent performance as a cancer-imaging agent when using PET-CT, there are some settings in which other radiopharmaceuticals offer advantages. This atlas, including about 500 high-quality images, is a user-friendly guide to PET-CT imaging beyond FDG.

The field of nuclear medicine has evolved rapidly in recent years, and one very important aspect of this progress has been the introduction of hybrid imaging systems. PET-CT has already gained widespread acceptance in many clinical settings, especially within oncology, and now SPECT-CT promises to emulate its success.