M. Krawczak – författare

Thrombotic disease is a major cause of death and disablement in Western society. The most common causes is an inherited defect in one of the many genes encoding a protein which is involved in clotting, It''s regulation or the process of clot dissolution, Fibrinolysis.

Venous Thrombosis: from genes to clinical medicine, presents our current knowledge of potentially prothrombotic protein at modalities, together with the clear and concise views of the roles these proteins play in haemostasis, and the use of molecular techniques in the analysis and diagnosis of inherited defects. Each chapter describes a specific protein deficiency, with information on protein structure, function and biochemistry, gene structure and expression, as well as epidemiological and molecular genetic aspects of the deficiency state.

This multifaceted approach aims to examine the possible causes of venous thrombosis, to explain the underlying molecular defects, and to explore the genotype-phenotype relationship in this complex multi gene disorder. The potential roles of both aesthetic interactions and environmental risk factors are also discussed. This book will be of value to haematologists, genetic counsellors and clinical geneticists.

Thrombotic disease is a major cause of death and disablement in Western society. The most common causes is an inherited defect in one of the many genes encoding a protein which is involved in clotting, It''s regulation or the process of clot dissolution, Fibrinolysis.

Venous Thrombosis: from genes to clinical medicine, presents our current knowledge of potentially prothrombotic protein at modalities, together with the clear and concise views of the roles these proteins play in haemostasis, and the use of molecular techniques in the analysis and diagnosis of inherited defects. Each chapter describes a specific protein deficiency, with information on protein structure, function and biochemistry, gene structure and expression, as well as epidemiological and molecular genetic aspects of the deficiency state.

This multifaceted approach aims to examine the possible causes of venous thrombosis, to explain the underlying molecular defects, and to explore the genotype-phenotype relationship in this complex multi gene disorder. The potential roles of both aesthetic interactions and environmental risk factors are also discussed. This book will be of value to haematologists, genetic counsellors and clinical geneticists.

This two volume set of books constitutes the proceedings of the 2014 7th IEEE International Conference Intelligent Systems (IS), or IEEE IS’2014 for short, held on September 24‐26, 2014 in Warsaw, Poland. Moreover, it contains some selected papers from the collocated IWIFSGN''2014-Thirteenth International Workshop on Intuitionistic Fuzzy Sets and Generalized Nets.The conference was organized by the Systems Research Institute, Polish Academy of Sciences, Department IV of Engineering Sciences, Polish Academy of Sciences, and Industrial Institute of Automation and Measurements - PIAP.The papers included in the two proceedings volumes have been subject to a thorough review process by three highly qualified peer reviewers.Comments and suggestions from them have considerable helped improve the quality of the papers but also the division of the volumes into parts, and assignment of the papers to the best suited parts.