Mark Sanderson – författare
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7 produkter
7 produkter
Häftad, Engelska, 2015
155 kr
Skickas inom 5-8 vardagar
London, 1938. With a world war on the horizon, a shocking crime begins to unfold – and one reporter knows too much to be allowed to survive. An absorbing and gripping mystery from the critically acclaimed author of SNOW HILL.November, 1938. Europe is teetering on the edge of war…Anti-Semitism is on the rise in Britain, and a serial killer is at work in London.Johnny Steadman, investigative journalist, is called to the scene of a gruesome murder – a man has been tied to his bed, mutilated and left to bleed to death. This is the second time the killer has struck, and it won’t be the last. Together with DC Matt Turner, Johnny tries desperately to find a link between the victims.When the next Mayor of London is subjected to a vicious Anti-Semitic attack, Johnny begins to wonder if the two cases are connected. Against a backdrop of escalating violence in Nazi Germany, he uncovers a shocking conspiracy that could bring the United Kingdom to its knees. But will Johnny live to tell the tale?
Häftad, Engelska, 2021
1 089 kr
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Principles of Nucleic Acid Structure, Second Edition, provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussions of X-ray crystallography, NMR, molecular modelling and databases. The book's focus is on a survey of structures that are especially important for biomedical research and pharmacological applications. This updated edition includes the latest advances relevant to recognition of DNA and RNA by small molecules and proteins, including sections on RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes and short interfering RNA (siRNA).This reference is a must-have for those seeking an authoritative, comprehensive and up-to-date source on all aspects of nucleic acid structure, from basic first principles to details of recent research results. Completely updated, with an expanded section on protein-nucleic acid interactions that reflects major increases in our knowledge Defines technical terms for novices Includes a complete list of resources, including relevant online databases and software, as well as useful websites
Inbunden, Engelska, 2007
1 076 kr
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Macromolecular Crystallography is the study of macromolecules (proteins and nucleic acids) using X-ray crystallographic techniques in order to determine their molecular structure. The knowledge of accurate molecular structures is a pre-requisite for rational drug design, and for structure-based function studies to aid the development of effective therapeutic agents and drugs. The successful determination of the complete genome (genetic sequence) of several species (including humans) has recently directed scientific attention towards identifying the structure and function of the complete complement of proteins that make up that species; a new and rapidly growing field of study called 'structural genomics'. There are now several important and well-funded global initiatives in operation to identify all of the proteins of key model species. One of the main requirements for these initiatives is a high-throughput crystallization facility to speed-up the protein identification process. The extent to which these technologies have advanced, calls for an updated review of current crystallographic theory and practice. This practical reference book features the latest conventional and high-throughput methods, and includes contributions from a team of internationally recognized leaders and experts. It will be of relevance and use to graduate students, research scientists and professionals currently working in the field of conventional and high-throughput macromolecular crystallography.
Häftad, Engelska, 2012
193 kr
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Don't Look Now, released in 1973, confirmed director Nicolas Roeg as one of themost stylish and innovative British directors of the postwar period. Adaptedfrom a short story by Daphne du Maurier, it is both a complex study of howpeople come to terms with grief and a chilling tale of murder set among thecanals and churches of Venice. Featuring telling performances by Julie Christieand Donald Sutherland as the couple whose daughter has tragically died,Don't Look Now depicts the way in which the macabre and the everyday areintertwined.In his lucid, subtle account, Mark Sanderson describes the collaborationbetween director and actors that sustained the film's emotional richness.He returns to du Maurier's original text and to the traditions of Gothic writingthat underpin Don't Look Now's combination of horror, melodrama and blackcomedy. Sanderson examines the film's intricate visual style, uncovering theway in which particular motifs are used to amplify its depiction of two terribledeaths. He finds compensation for the film's grimly fatalistic view of life in itscelebration of sexual relationships and the power of recollection. The bookincludes an exclusive and in-depth interview with Roeg as well as rare andunpublished comments from Christie.In his foreword to this special edition, published to celebrate the 20thanniversary of the BFI Film Classics series, Jason Wood places Don't Look Nowin the context of Roeg's film-making careeer, and draws upon Roeg's revealinginsights into the film's production.
Del 8685 - Lecture Notes in Computer Science
Information Access Evaluation -- Multilinguality, Multimodality, and Interaction
5th International Conference of the CLEF Initiative, CLEF 2014, Sheffield, UK, September 15-18, 2014, Proceedings
Häftad, Engelska, 2014
561 kr
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This book constitutes the refereed proceedings of the 5th International Conference of the CLEF Initiative, CLEF 2014, held in Sheffield, UK, in September 2014.
Häftad, Engelska, 2004
561 kr
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During recent years, huge efforts have been made to establish digital libraries, in a variety of media, offered from a variety of sources, and intended for a variety of professional and private user communities. As digital data collections proliferate, problems of resource selection and data fusion become major issues. Traditional search engines, even the best ones, are unable to provide access to the hidden web of information that is only available via digital library search interfaces.Originating from the SIGIR 2003 Workshop on Distributed Information Retrieval, held in Toronto, Canada in August 2003, this book presents extended and revised workshop papers as well as several invited papers on the topic to round off coverage of the core issues. The papers are devoted to recent research on the design and implementation of methods and tools for resource discovery, resource description, resource selection, data fusion, and user interaction.
Häftad, Engelska, 2006
561 kr
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This volume contains the papers presented at the 13th International Symposium on String Processing and Information Retrieval (SPIRE), held October 11-13, 2006, in Glasgow, Scotland. The SPIRE annual symposium provides an opportunity for both new and established researchers to present original contributions to areas such as string processing (dictionary algorithms, text searching, pattern matching, text c- pression, text mining, natural language processing, and automata-based string processing); information retrieval languages, applications, and evaluation (IR modelling, indexing, ranking and ?ltering, interface design, visualization, cro- lingual IR systems, multimedia IR, digital libraries, collaborative retrieval, W- related applications, XML, information retrieval from semi-structured data, text mining, and generation of structured data from text); and interaction of biology and computation (sequencing and applications in molecular biology, evolution and phylogenetics, recognition of genes and regulatory elements, and sequen- driven protein structure prediction). The papers in this volume were selected from 102 papers submitted from over 20 di?erent countries in response to the Call for Papers. A total of 26 submissions were accepted as full papers, yielding an acceptance rate of about 25%. In view of the large number of good-quality submissions the Program Committee decided to accept 5 short papers, that have also been included in the proceedings. SPIRE 2006 also featured two talks by invited speakers: Jamie Callan (Carnegie Mellon University, USA) and Martin Farach-Colton (Rutgers University, USA).