Minoru Tanaka – författare

Explains the advantages of using medaka in experimental designs, to facilitate research, and to stimulate progress by adopting medaka as a model animal

The second volume of Medaka: Biology, Management, and Experimental Protocols, together with the first volume, helps to familiarize scientists with the advantages of using medaka in experimental designs, to facilitate research using medaka, and to stimulate progress by adopting medaka as a model animal. The second edition expands on the first by providing additional information and current protocols that have been recently developed, or modified, to successfully raise medaka fish under stable culture conditions in the laboratory.

This volume explores new technologies developed after 2009, using the fish as a molecular tool in the fields of life science, evolution, ecology, and toxicology. The authors—noted experts in the field—provide the latest information that spans the varied research disciplines and addresses the value to science of medaka''s adoption as a model animal. This important book:

Written for students and researchers in fish biology and aquaculture, Medaka: Biology, Management, and Experimental Protocols, Volume 2 introduces the cutting edge research in basic and applied biology using medaka as a model animal as well as descriptions of experimental methods and protocols.

Explains the advantages of using medaka in experimental designs, to facilitate research, and to stimulate progress by adopting medaka as a model animal

The second volume of Medaka: Biology, Management, and Experimental Protocols, together with the first volume, helps to familiarize scientists with the advantages of using medaka in experimental designs, to facilitate research using medaka, and to stimulate progress by adopting medaka as a model animal. The second edition expands on the first by providing additional information and current protocols that have been recently developed, or modified, to successfully raise medaka fish under stable culture conditions in the laboratory.

This volume explores new technologies developed after 2009, using the fish as a molecular tool in the fields of life science, evolution, ecology, and toxicology. The authors—noted experts in the field—provide the latest information that spans the varied research disciplines and addresses the value to science of medaka''s adoption as a model animal. This important book:

Written for students and researchers in fish biology and aquaculture, Medaka: Biology, Management, and Experimental Protocols, Volume 2 introduces the cutting edge research in basic and applied biology using medaka as a model animal as well as descriptions of experimental methods and protocols.

Oryzias latipes, known as medaka, is a model organism from East Asia. Breeding of this small, egg-laying freshwater teleost fish has long been popular among hobbyists in Japan. Now, as biological science has entered the genome era, the medaka provides significant advantages that make it one of the most valuable vertebrate models: a large collection of spontaneous mutants collected over a century, the presence of highly polymorphic inbred lines established over decades, and a recently completed genome sequence. This book is the first comprehensive monograph to cover a variety of medaka research. It opens with a historical view of medaka, followed by a series of research topics in the four major areas where the medaka is increasingly important: genomics, genetics, and resources; organogenesis and disease models; germ cells, sex determination, and reproduction; and evolution. Readers will find state-of-the-art information on medaka genetics and genomics such as the first isolation of active transposons in vertebrates, the influence of chromatin structure on sequence variation, fine QTL analysis, and versatile mutants as human disease models.

This book introduces cutting-edge studies on the spectrum of sex. The sex spectrum can be understood as an interwoven mechanism sustaining graded phenotypes between the two sexes. The book overviews three elements that develop the sex spectrum: genetics, the endocrine system, and the environment. Part I discusses the genetic regulation during sex determination, which often results in a mixture of two sexes or sex reversal. The evolutionary aspects of the genetic determinants are also discussed. Part II presents the involvement of endocrine regulation in the sex spectrum, which covers a broad range of phenotypic events, including sexual behavior and metabolism. Interestingly, sex hormones can also act as sex determinants. Finally, Part III shows that intrinsic factors, such as sex-determining genes and sex hormones, are not the only factors in sex development. The environment surrounding organisms, such as symbiosis and metabolism, act on the sex as critical factors, generating the sex spectrum. Determination and development of the two sexes have been a topic of great interest and a long-standing issue in biology. The book updates the conventional view that biological sex is fixed after birth and sets new perspectives for understanding sex as a spectrum manifested in multiple phenomena. Each chapter contributed by leading experts explains the sex spectrum in various organisms and their underlying mechanisms from the latest ongoing studies. The book provides a valuable resource for not only experts in developmental biology, physiology, and medical science, but also non-scientists and anyone interested in the topic.