Muralikrishnan Dhanasekaran – författare

Advanced Drug Delivery Systems for Colonic Disorders presents state-of-the-art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency. Chapters allow readers to not only become familiar with advancements, but also understand concepts by providing illustrations, figures, and informative tables. Contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the status of clinical trials.This book is the perfect resources for researchers in pharma, biomaterials, and nutrition to help familiarize them with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications.

Covers recent perspectives and challenges towards the treatment of colonic disordersProvides insights into how advanced drug delivery systems can be effectively used for the management of various types of colonic disordersDiscusses drug delivery strategies to manage inflammatory bowel disease (chronic inflammation in the digestive tract), ulcerative colitis (inflammation and ulcers in colon), Crohn's disease, Colonic polyps, Shigellosis, Colon Bleeding or Hemorrhage, Diverticulosis and colon cancer

Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management explores innovative drug delivery systems utilizing nanotechnology to revolutionize the treatment and management of COPD. By presenting the latest advancements in nanotechnologies-including polymeric nanoparticles, liposomes, and theranostic nanoparticles-this volume aims to enhance patient outcomes, alleviate symptoms, and improve lung function, thereby addressing the urgent need for more effective therapies. Structured to cater to a diverse audience, from beginners to advanced researchers, this comprehensive text begins with an overview of COPD, its epidemiology, and current limitations in treatment. The core chapters explore a wide range of nanotechnological applications for diagnosis and disease management, including cutting-edge topics such as nano-immunotherapy and green nanotechnology. Each chapter was developed by a multidisciplinary team of experts from academia and industry, ensuring a comprehensive approach that integrates insights from pharmaceutical sciences, respiratory health, and bioinformatics. Nanotechnology-based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management not only fills a critical gap in COPD literature but also serves as an invaluable resource for researchers, clinicians, and students alike. It promises to be a definitive guide on how innovative drug delivery systems can transform COPD care, paving the way for future advancements in respiratory health management.Highlights cutting-edge nanotechnologies transforming COPD treatment and management for improved patient outcomesDiscusses future directions and challenges in nanotechnology applications for COPD managementServes as a valuable resource for researchers, clinicians, and students in respiratory health fieldsOffers comprehensive coverage of innovative drug delivery systems for effective COPD diagnosis and therapyIntegrates multidisciplinary insights from experts in pharmaceutical sciences, respiratory health, and bioinformatics

Computational methods and understanding computational models are important in modern drug discovery. The book focuses on computational approaches that can improve the development of in silico methodologies. It includes lead hit methods, docking algorithms, computational chiral compounds, structure-based drug design, GROMACS and NAMD, structural genomics, toxicity prediction, enzyme inhibitors and peptidomimetic therapeutics

The book bridges the gap between pharmaceutics and molecular modelling at the micro, meso and macro scale. It covers Lipinski's rule of five, nanoparticulate drug delivery, computational prediction of drug solubility and ability to cross blood brain barrier, computer-based simulation of pharmacokinetic parameters, virtual screening of mucoadhesive polymers, QSPR modelling, designing of 2D nanomaterials and role of principal component analysis.

Presents the latest R & D information on medicinal mushrooms from diverse geographical locationsOffers comprehensive coverage of the most important application areas of medicinal mushroomsIncludes contributions by eminently experienced researchers in the field of medicinal mushroomsMedicinal mushrooms are increasingly gaining attention worldwide because of their pharmacologically bioactive compounds, which have demonstrated potent and unique clinical properties. Scientific studies carried out during the last decade have confirmed their efficacy in treating a wide range of diseases. Extracts and bioactive compounds obtained from mushrooms have been used medicinally as anticancer, immunomodulator, antibacterial, antiviral, anti-inflammatory, anti-atherosclerotic, neuroprotectant, cardioprotectant, antioxidant, and anti-hypoglycemic agents, and in stem cell-based therapies.Introducing readers to the latest developments in, and ongoing research efforts on, medicinal mushrooms, this book gathers articles contributed by eminent researchers in different disciplines and from around the globe. Highlighting the tremendous potential of mushrooms for the development of new drugs, the topics covered include but are not limited to:Recent progress in research on the pharmaceutical potential of medicinal mushrooms and prospects for their clinicalapplicationEdible mushroom neuronutraceuticals: Basis of therapeuticsOverview of therapeutic efficacy of mushroomsMushrooms – a wealth of resources for prospective stem cell-based therapiesMushrooms as potential natural cytostatics

Presents the latest R & D information on medicinal mushrooms from diverse geographical locationsOffers comprehensive coverage of the most important application areas of medicinal mushroomsIncludes contributions by eminently experienced researchers in the field of medicinal mushroomsMedicinal mushrooms are increasingly gaining attention worldwide because of their pharmacologically bioactive compounds, which have demonstrated potent and unique clinical properties. Scientific studies carried out during the last decade have confirmed their efficacy in treating a wide range of diseases. Extracts and bioactive compounds obtained from mushrooms have been used medicinally as anticancer, immunomodulator, antibacterial, antiviral, anti-inflammatory, anti-atherosclerotic, neuroprotectant, cardioprotectant, antioxidant, and anti-hypoglycemic agents, and in stem cell-based therapies.Introducing readers to the latest developments in, and ongoing research efforts on, medicinal mushrooms, this book gathers articles contributed by eminent researchers in different disciplines and from around the globe. Highlighting the tremendous potential of mushrooms for the development of new drugs, the topics covered include but are not limited to:Recent progress in research on the pharmaceutical potential of medicinal mushrooms and prospects for their clinicalapplicationEdible mushroom neuronutraceuticals: Basis of therapeuticsOverview of therapeutic efficacy of mushroomsMushrooms – a wealth of resources for prospective stem cell-based therapiesMushrooms as potential natural cytostatics

The book contains review articles on the latest evidence-based scientific knowledge and future insights on industrial hemp applications ranging from sustainable agriculture, sustainable development, and commercial uses of hemp-derived innovative products. The research articles evaluate and review the latest research and development on hemp’s agronomy, ecophysiology, the opportunities and challenges of hemp cultivation in the different regions of the world, including Africa.The book reviews complete patent literature on hemp from the publication of the first patent in 1856 till the end of 2020, providing an excellent insight into hemp’s business growth and future potential for industrial applications along with region- and sector-wise patenting activity concerning industrial hemp. In addition, articles describe the applications of hemp-derived green materials for building construction, wastewater treatment, and water purification.  The book will be useful as a referencebook for students, researchers, farmers, business houses, and individuals interested in industrial hemp for commercial aspects, sustainable development, farming, and other hemp-derived innovative products.

The book contains review articles on the latest evidence-based scientific knowledge and future insights on industrial hemp applications ranging from sustainable agriculture, sustainable development, and commercial uses of hemp-derived innovative products. The research articles evaluate and review the latest research and development on hemp’s agronomy, ecophysiology, the opportunities and challenges of hemp cultivation in the different regions of the world, including Africa.The book reviews complete patent literature on hemp from the publication of the first patent in 1856 till the end of 2020, providing an excellent insight into hemp’s business growth and future potential for industrial applications along with region- and sector-wise patenting activity concerning industrial hemp. In addition, articles describe the applications of hemp-derived green materials for building construction, wastewater treatment, and water purification.  The book will be useful as a referencebook for students, researchers, farmers, business houses, and individuals interested in industrial hemp for commercial aspects, sustainable development, farming, and other hemp-derived innovative products.

The book contains review articles providing a comprehensive overview of cannabis/marijuana’s diverse healing aspects in human healthcare (medicinal, nutraceutical, skincare, etc.).

The book contains review articles providing a comprehensive overview of cannabis/marijuana’s diverse healing aspects in human healthcare (medicinal, nutraceutical, skincare, etc.). The research articles include the role of cannabis in cancer treatment, drug discovery, cosmeceutical potential, prophylactic and therapeutic use for treating neuropathic pain and migraine, pharmacokinetics, safety profile, and issues related to the consumption of cannabis/marijuana. Another salient feature of the book is a complete mapping and region- and sector-wise critical analysis of cannabis/marijuana patents on healthcare and future directions for the benefit of researchers and businesses/entrepreneurs interested in the rapidly advancing area of cannabis.The text describes cannabis/marijuana’s detailed legal aspects, production prospects, and applications for healthcare and recreational purposes in the USA. It traces the traditional roots of cannabis use in Turkey, Israel, the Middle East, Africa, and India.  This unique compendium of articles will be useful as a reference book for students, researchers, academics, business houses, and all individuals interested in medicinal, nutraceutical, cosmeceutical, traditional, legal, and commercial aspects of cannabis usage.

The book presents new and novel perceptions about ailments alleviating the effects of several mushroom species.

The book presents new and novel perceptions about ailments alleviating the effects of several mushroom species.

The ever-rising increase in the consumption of medicinal herbs and its products and its exposure in the human population have generated concerns about the potential neurotoxicity of several new and existing botanicals.

The ever-rising increase in the consumption of medicinal herbs and its products and its exposure in the human population have generated concerns about the potential neurotoxicity of several new and existing botanicals.

This book discusses the role of artificial intelligence in neurological disorders, including, alleviating movement disorders, psychiatric disorders, diagnosis of neurological and neurodegenerative disorders, dementia, neuronal cancer, neuronal Infections, and brain diseases.

This book discusses the role of artificial intelligence in neurological disorders, including, alleviating movement disorders, psychiatric disorders, diagnosis of neurological and neurodegenerative disorders, dementia, neuronal cancer, neuronal Infections, and brain diseases. It explores applications of artificial intelligence in the early diagnosis, prognosis, and development of new therapies against neurodegenerative disorders. This book also provides cutting-edge research using AI for studying neuroimage analysis, toward the discovery of new biological pathways and systems implicated in dementia and related diseases. It also reviews AI-based interventions in depression research and treatment. The chapter also examines the potential benefits of using AI to help manage depression, from improved access to coordinated care. This book is an essential source for students, researchers, academicians, and neurologists aiming to understand AI-based approaches for the diagnosis, treatment, and prevention of neurological disorders.

This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications.