Kamal Dua – författare

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models.

The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development.

Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index.

This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations.

Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer.

Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way. The book covers recent developments in advanced drug delivery systems in various metabolic disorders, including disturbances in protein, lipid, carbohydrate and hormone metabolism and lysosomal and mitochondrial disorders. It provides a brief introduction to metabolic disorders, along with a focus on the current landscape and trends in understanding disease pathology using different in vitro and in vivo models required for clinical applications and developments of new therapeutics.

Each subsequent chapter covers drug delivery systems dedicated to metabolic diseases caused by disturbances in protein, lipid, carbohydrate and hormone metabolism. Then, it moves on to cover lysosomal storage disorders and applications of phytopharmaceuticals in this context. This is the perfect reference for researchers in pharmaceutical science who are interested in developing new treatments for metabolic diseases.

Offers comprehensive coverage of drug delivery to treat metabolic diseases Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of metabolic disorders Includes the most recent research on diagnostic methods and treatment strategies using controlled drug delivery systems

Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field.

Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation.

Identifies recent developments and current trends in anti-inflammation therapy Discusses advanced chemotherapeutics, SAR analysis of novel pharmacophores and natural products Outlines the pathophysiology of inflammatory pathways in the pathogenesis of disease onset, including strategies to counter these intricacies Contains a blend of editors from both academia and industry

Novel Drug Delivery Systems in the Management of CNS Disorders offers a comprehensive source of information on delivering drugs to the central nervous system to treat various diseases and conditions. The book covers a wide range of CNS disorders, including epilepsy, Parkinson's, Alzheimer's, Huntington's, multiple sclerosis, schizophrenia, cerebral palsy, autism, ALS, and others.The book begins by presenting the foundations of drug delivery to the brain and addressing the associated challenges. It then delves into clinical trials and explores the future potential of the presented technologies.This reference is designed for drug delivery researchers in academia and corporations, providing them with the essential knowledge about overcoming the Brain-Blood Barrier and achieving targeted drug delivery to the central nervous system.

Consolidates current state of the art research into a single book volumePresents the challenges of drug delivery to the CNS in a comprehensive wayCovers the most relevant CNS conditions and diseasesProvides future perspectives and the most active research areas in this fast-moving field

Advanced Drug Delivery Systems for Colonic Disorders presents state-of-the-art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency. Chapters allow readers to not only become familiar with advancements, but also understand concepts by providing illustrations, figures, and informative tables. Contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the status of clinical trials.This book is the perfect resources for researchers in pharma, biomaterials, and nutrition to help familiarize them with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications.

Covers recent perspectives and challenges towards the treatment of colonic disordersProvides insights into how advanced drug delivery systems can be effectively used for the management of various types of colonic disordersDiscusses drug delivery strategies to manage inflammatory bowel disease (chronic inflammation in the digestive tract), ulcerative colitis (inflammation and ulcers in colon), Crohn's disease, Colonic polyps, Shigellosis, Colon Bleeding or Hemorrhage, Diverticulosis and colon cancer

Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorders focuses on 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modeling. The book, written by a team of leading experts in the field, is an essential resource for anyone interested in the future of CRD treatment. Chapters discuss the emerging therapeutic approaches for CRDs, including biologicals and phytoceuticals. Core chapters of the book then cover the application of 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modeling to different CRDs. The book concludes with a discussion of the current clinical trials and future prospects for the management of CRDs.This is a valuable resource for researchers, clinicians, and other healthcare professionals who are interested in the latest technological advances in the field of CRDs. It will also be of interest to students and scientists working in the fields of pharmaceutical sciences, microfluidics, bioinformatics, drug design, drug delivery, and 3D printing.Provides the most recent and updated perspectives and challenges in the management of chronic respiratory disordersCovers exciting new technologies such as 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modellingIncludes the most recent information on the development of advanced drug delivery systems for the treatment of chronic respiratory disorders

Lung Cancer and Environmental Toxicants aims to explore the intricate relationship between lung cancer and environmental toxicants, shedding light on a hidden link that demands urgent attention. This groundbreaking book addresses a critical gap in the current literature by introducing a pioneering exploration of the interplay between lung cancer and environmental toxicants. Previous articles have not coalesced into a comprehensive examination of the complex connection between lung cancer development and the diverse array of environmental toxicants. This book delves into the latest scientific research and clinical findings to offer a clear way forward for healthcare workers to assess and treat lung cancer patients who may have been exposed to these substances. "Lung Cancer and Environmental Toxicants" provides a precise view of the impact of environmental toxicants on lung cancer, covering various aspects including epidemiology, molecular mechanisms, exposure pathways, and preventive measures. This unique and timely work will pave the way for a deeper understanding of the underexplored factors contributing to lung cancer incidence, offering novel insights into the role of various toxic substances in disease causation. This significant title will catalyze new avenues of research and awareness in the fields of oncology, environmental health, and public policy.Unlocks the intricate nexus between lung cancer and environmental toxicants, offering an unprecedented exploration of complex mechanisms and interactions for advancing research in oncology and environmental healthTakes a global perspective on lung cancer and environmental toxicants, considering the prevalence of the disease and its causes in different regions of the world, as well as addressing the challenges faced by developing nationsPresents rigorous, evidence-based research on the effects of toxicants on the human lung, ensuring the book’s indispensability

Innovative Targeting Strategies in Breast Cancer Therapy is a comprehensive reference addressing the challenge of non-specific drug distribution in the body, along with severe toxicity and adverse effects, by offering insights into targeted breast cancer treatment. It further educates researchers on formulating and developing novel carriers with target-specific attributes (such as targeted liposomes, nanoparticles, micelles, and dendrimers), contributing to a more refined approach to breast cancer. This book's content is presented in 12 chapters. The first chapters introduces the reader to the different breast cancer therapies followed by indepth information on targeting . Recognizing the need for targeted drug delivery in breast cancer treatment, this book presents an encompassing compilation of advanced research and formulation strategies. By focusing on effectively targeting cancer cells, the book mitigates dose-related toxicity associated with cytotoxic drugs, providing a comprehensive resource for improved treatment approaches. Research in oncology, pharmacology, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.Delves into the intricacies of delivering drugs in cancer precisely to designated sites through molecular recognitionProvides in-depth coverage of existing market formulations, ongoing clinical trials, and intellectual property rights pertaining to targeted breast cancer therapiesOffers researchers up-to-date insights into breast cancer targeting strategies

Nutrition and Women's Health: Functional Foods, Nutraceuticals, and Integrative Strategies delves into the critical role nutrition plays in human health, highlighting its growing importance among healthcare providers, research scientists, nutritionists, and dietitians. Despite significant progress, there remains a lack of targeted research specifically addressing women's nutritional needs at various life stages. This book aims to fill that gap, offering comprehensive insights into the benefits of nutraceuticals and functional foods for disease prevention, treatment, and recurrence through different phases of a woman's life.The book covers a wide range of topics, including nutritional modules for teenage nutrition, the interaction of sex hormones, menopause management, polycystic ovary syndrome, fertility, and bone, skin, and heart health. It emphasizes the underlying causes of various pathophysiological conditions linked to nutrition and provides practical diet plans to help avoid health issues across various age groups. Expert authors present evidence-based strategies for improving women's health through nutrition, making this book an invaluable resource for professionals and individuals alike.Explores the benefits of nutraceuticals for prevention, treatment, and recurrence of disease through women's various life stagesDemonstrates the role of nutraceuticals essential for women to help circumvent health issues at different life stagesHighlights nutrition management for polycystic ovary syndromeDiscusses the impact of nutrition to balance hormonal and gynecological healthExamines dietary choices to maintain optimal cardiovascular health

Bio-Click Chemistry: Expanding Horizons Beyond the Click delves into the dynamic intersection of biocatalysis and click chemistry, providing a comprehensive exploration of these rapidly evolving fields. This book offers in-depth insights into both historical perspectives and the latest advancements, ensuring readers gain a thorough understanding of fundamental principles, practical applications, and future directions. Readers will discover the versatile applications of biocatalysis and click chemistry in pharmaceuticals, biotechnology, biology, biomedicine, nanomedicine, and materials science, equipping researchers, educators, and industry professionals with the tools and techniques needed to foster innovation and real-world impact. Furthermore, the book investigates the emerging trends, challenges, and opportunities in biocatalysis and click chemistry, empowering readers to stay ahead of the curve and drive transformative developments in chemical synthesis and enzymatic engineering. This indispensable guide is designed for researchers, educators, and industry professionals dedicated to advancing their work and exploring new frontiers in chemical synthesis and biocatalytic processes.Provides comprehensive coverage of biocatalysis and click chemistry, offering in-depth insights into historical perspectives and cutting-edge advancementsExplores practical applications and methodologies, equipping researchers, educators, and industry professionals with invaluable tools and techniquesInvestigates future directions, with expert analysis on emerging trends, challenges, and opportunities in biocatalysis and click chemistry

Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management explores innovative drug delivery systems utilizing nanotechnology to revolutionize the treatment and management of COPD. By presenting the latest advancements in nanotechnologies-including polymeric nanoparticles, liposomes, and theranostic nanoparticles-this volume aims to enhance patient outcomes, alleviate symptoms, and improve lung function, thereby addressing the urgent need for more effective therapies. Structured to cater to a diverse audience, from beginners to advanced researchers, this comprehensive text begins with an overview of COPD, its epidemiology, and current limitations in treatment. The core chapters explore a wide range of nanotechnological applications for diagnosis and disease management, including cutting-edge topics such as nano-immunotherapy and green nanotechnology. Each chapter was developed by a multidisciplinary team of experts from academia and industry, ensuring a comprehensive approach that integrates insights from pharmaceutical sciences, respiratory health, and bioinformatics. Nanotechnology-based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management not only fills a critical gap in COPD literature but also serves as an invaluable resource for researchers, clinicians, and students alike. It promises to be a definitive guide on how innovative drug delivery systems can transform COPD care, paving the way for future advancements in respiratory health management.Highlights cutting-edge nanotechnologies transforming COPD treatment and management for improved patient outcomesDiscusses future directions and challenges in nanotechnology applications for COPD managementServes as a valuable resource for researchers, clinicians, and students in respiratory health fieldsOffers comprehensive coverage of innovative drug delivery systems for effective COPD diagnosis and therapyIntegrates multidisciplinary insights from experts in pharmaceutical sciences, respiratory health, and bioinformatics

Green Polymeric Materials in Drug Delivery: Sustainable Solutions for Therapeutic Applications addresses the critical intersection of polymer science, pharmaceutical technology, and environmental sustainability. This reference responds to the urgent need for eco-friendly drug delivery systems that improve therapeutic outcomes while minimizing ecological impact. It offers researchers and professionals a detailed exploration of green polymers derived from renewable sources and their transformative potential in healthcare. The comprehensive contents cover fundamental principles, synthesis, biocompatibility, formulation strategies, and innovative applications including nanomaterials, hydrogels, vesicular systems, and vaccine delivery. Chapters authored by leading experts examine targeted delivery routes such as mucosal, ocular, transdermal, and neural pathways. Regulatory frameworks and clinical trial insights further support translation from research to practice. Emerging technologies like AI-assisted formulation and 3D printing of implants are also discussed. This reference benefits polymer chemists, pharmaceutical scientists, regulatory experts, and clinicians by providing authoritative knowledge on sustainable materials for drug delivery. It equips readers with the scientific foundation and practical case studies necessary to advance green polymeric technologies in therapeutic development, fostering a sustainable future in pharmaceutical innovation and patient care.Explores diverse drug delivery strategies using sustainable polymersProvides comprehensive overview of green polymeric materials and their synthesisHighlights environmental benefits and reduced carbon footprintDiscusses regulatory considerations for clinical translationShowcases real-world case studies demonstrating therapeutic efficacy

This book discusses the potential application of self-nanoemulsifying drug delivery systems (SNEDDS) in different inflammatory diseases. It introduces the fundamental principles of SNEDDS, their formulation components, and characterization techniques, providing insights into their mechanisms of drug delivery and formulation optimization. The book also explores the potential of various combination therapies with SNEDDS, highlighting strategies, synergistic effects, and challenges. Furthermore, the chapters in the book highlight the applications of SNEDDS in specific inflammatory diseases, including diabetes, brain diseases, colorectal diseases, cardiovascular diseases, lung diseases, and cancer. Towards the end, the book evaluates the potential toxic effects of SNEDDS components and addresses safety considerations, regulatory aspects, patents, and clinical trials pertaining to SNEDDS. This book is intended for researchers, pharmacologists, pharmaceutical scientists, and clinicians involved in drug delivery and nanomedicine.

This book reviews the evolving field of epigenetics and its implications for drug discovery and precision medicine. It also focuses on the intricate mechanisms governing gene regulation and the impact of epigenetics on health and disease. The book encompasses the complexities of epigenetic mechanisms and their role in diseases such as cancer, autoimmune disorders, inflammatory conditions, and neurodegenerative diseases. Additionally, it examines the role of miRNA as an epigenetic drug in treating cancer and in-silico approaches to epigenetic drug discovery. The book uncovers the potential of epigenetic drug discovery, including insights into traditional medicine, marine sources, and OMICS technologies. Moreover, it explores the interplay between gut microbiota, probiotics, and prebiotics in epigenetic therapeutic approaches. With a focus on personalized medicine and recent advancements in drug delivery systems, this book is intended for researchers, clinicians, and pharmaceutical professionals seeking to explore epigenetic drug discovery and development.Key featuresDiscusses the implications of epigenetic mechanisms in different diseases and epigenetic based drug discoveryReviews development of targeted therapies based on epigenetic mechanisms for cancer, autoimmune diseases, neurodegenerative conditions, and inflammatory diseasesEmphasizes the importance of precision medicine and personalized therapies based on epigenetic profilingExplores application of artificial intelligence in designing novel delivery systems for epigenetic drugsPresents role of advance in-silico and drug discovery tools in the development of epigenetic drugs

This book provides a comprehensive overview of synthetic polymers and their applications in designing delivery systems for the management of inflammatory diseases. It presents introductory insights into inflammatory conditions, delves into the role of synthetic polymers, and examines diverse delivery approaches. Synthetic Polymeric Materials-Based Drug Delivery Systems for Inflammatory Diseases explores the potential of synthetic polymers in designing drug delivery systems for managing inflammatory diseases, including inflammatory lung diseases, inflammatory bowel diseases, and inflammatory skin diseases, as well as other conditions like cancer, neurodegenerative disorders, rheumatoid arthritis, and eye-related inflammatory conditions. It also discusses the role of synthetic polymers in modulating immune system responses in different disease conditions. Furthermore, it analyzes the 3D printing technologies employed for the preparation of drug delivery systems based on synthetic polymers. Toward the end, the book highlights the challenges and prospects of synthetic polymers in designing delivery systems for the effective management of inflammatory diseases and their clinical usage. This book is intended for researchers and professionals in the fields of pharmaceutical sciences, nanotechnology, and drug delivery systems.Key FeaturesHighlights the role of a synthetic polymer-based drug delivery system against inflammatory responsesExplores the cutting-edge technology of 3D printing and its application in preparing drug delivery systems based on synthetic polymersProvides valuable insights into how synthetic polymers can be used to modulate immune system responsesPresents regulatory compliance using synthetic polymers in drug delivery systems for inflammatory diseasesExamines challenges associated with synthetic polymers in drug delivery systems for inflammatory diseases

This book comprehensively reviews the intricate relationship between environmental toxicants and the gut microbiome. It explores the role of dietary choices and lifestyle in shaping and modulating the gut microbiome’s response to environmental toxicants. It examines the intricate relationship between these toxic substances and the composition, function, and overall health implications of the gut microbiome. The chapters provide in-depth insights into the impacts of various toxicants, such as phthalates, pesticides, organic pollutants, bisphenols, and heavy metals, on the delicate microbial balance within our digestive systems. Specific chapters address the impact of lead, mercury, cadmium, and arsenic on the composition and function of the gut microbiome. The book concludes by addressing future prospects and challenges in understanding and mitigating the impacts of environmental toxicants on the gut microbiome and highlighting the importance of these efforts.Key Features:Provides a comprehensive examination of the intricate relationship between environmental toxicants and the gut microbiomeReviews the possible mechanisms underlying bidirectional interactions between environmental pollutants and GIExamines the role of dietary choices and lifestyle factors in modulating the gut microbiome's response to environmental toxicantsCovers the impact of toxic substances, phthalates, pesticides, and heavy metals on the gut microbiomeExplores the practical implications of toxicant exposure on human healthThis book is intended for researchers and scientists working in the fields of environmental toxicology, microbiology, pharmacology, and related disciplines.

This book offers a comprehensive overview of the epidemiology, etiology, and pathophysiology of chronic obstructive pulmonary disease (COPD). It addresses the limitations of existing drug delivery methods and explores advanced delivery systems to overcome these challenges, providing an exhaustive account of their intricate mechanisms. The introductory chapters elucidate pathways responsible for COPD progression, followed by a detailed analysis of established biomarkers and potential targets in contemporary COPD therapy. Subsequent chapters provide insights into ongoing treatment modalities, their efficacy, drawbacks, and prospective solutions to counter the setbacks of COPD therapy. The subsequent section covers state-of-the-art drug delivery technologies and novel drug formulations designed to enhance drug deposition and absorption in COPD lungs. It further explores a methodical yet coordinated explanation of targeted personalized therapies and emerging approaches, including nanoparticles, polymeric carriers, and vesicular delivery systems. Toward the end, the book discusses ongoing and completed clinical trials encompassing the management of COPD through advanced drug delivery approaches. It serves as a valuable resource for professionals, scientists, academicians, and clinicians specializing in respiratory health.Provides an in-depth understanding of the epidemiology, etiology, and pathophysiology of Chronic Obstructive Pulmonary Disease (COPD)Delve into pathways responsible for COPD progression, conducting a detailed analysis of established biomarkers and potential targets in contemporary COPD therapyOffer insights into ongoing treatment modalities, evaluating their efficacy, drawbacks, and proposing prospective solutions to counter the setbacks of COPD therapySystematically organizes information on state-of-the-art drug delivery technologies and novel formulations designed to enhance drug deposition and absorption in COPD lungsPresents a methodical explanation of targeted personalized therapies and emerging approaches, including nanoparticles, polymeric carriers, and vesicular delivery systems

This book examines the role of nanotechnology in transforming the diagnosis, treatment, and management of lung cancer. The initial chapters introduce lung cancer through its epidemiology, pathophysiology, and immunological mechanisms. The subsequent chapters emphasize the role of novel nanoparticles in early detection and imaging of lung cancer. The book then explores the potential of different nanomaterials, such as metal and metal oxide nanoparticles, nano micelles, carbon nanotubes, liposomes, polymeric nanoparticles, solid lipid nanoparticles, dendrimers, nanofibers, and quantum dots, in lung cancer treatment. Each chapter focuses on the unique properties from targeted drug delivery to improved bioavailability and reduced side effects. Exploring theragnostic nanoparticles, the book highlights their dual role in diagnosis and therapy, alongside nano-immunotherapy strategies for improved cancer treatment.The book concludes with a critical review of ongoing clinical trials, offering insights into the future of nanotechnology-based lung cancer therapies and emerging trends in the field.Key Features:Details the epidemiology and pathophysiology of lung cancer, covering disease prevalence, risk factors, and cellular mechanismsExamines the diagnostic capabilities of nanotechnology, emphasizing the use of nanoparticles in early detection and imagingExplores the therapeutic potential of various nanomaterials, such as liposomes, dendrimers, and quantum dots, for enhanced drug delivery and treatmentHighlights theranostic nanoparticles, combining diagnostic and therapeutic functions for personalized cancer careReviews clinical trials and emerging trends, providing insights into the future of nanotechnology-based lung cancer therapiesThe book is intended for researchers of oncology, nanomedicine, pharmaceutical sciences, and biomedical engineering.

Computational methods and understanding computational models are important in modern drug discovery. The book focuses on computational approaches that can improve the development of in silico methodologies. It includes lead hit methods, docking algorithms, computational chiral compounds, structure-based drug design, GROMACS and NAMD, structural genomics, toxicity prediction, enzyme inhibitors and peptidomimetic therapeutics

The book bridges the gap between pharmaceutics and molecular modelling at the micro, meso and macro scale. It covers Lipinski's rule of five, nanoparticulate drug delivery, computational prediction of drug solubility and ability to cross blood brain barrier, computer-based simulation of pharmacokinetic parameters, virtual screening of mucoadhesive polymers, QSPR modelling, designing of 2D nanomaterials and role of principal component analysis.

This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases.The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders.Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress.Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress.

This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases.The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders.Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress.Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress.

This book reviews the role of the lung microbiome in the development and progression of lung diseases. It further highlights the potential role of lung microbiota as the key modulator of lung carcinogenesis and immune response against cancer cells.

This book reviews the role of the lung microbiome in the development and progression of lung diseases. It further highlights the potential role of lung microbiota as the key modulator of lung carcinogenesis and immune response against cancer cells.

The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment.

The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment.

This book comprehensively reviews the recent developments of natural polymers for drug delivery systems in various lung disorders.