Sachin Kumar Singh – författare

Advanced Drug Delivery Systems for Colonic Disorders presents state-of-the-art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency. Chapters allow readers to not only become familiar with advancements, but also understand concepts by providing illustrations, figures, and informative tables. Contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the status of clinical trials.This book is the perfect resources for researchers in pharma, biomaterials, and nutrition to help familiarize them with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications.

This book discusses the potential application of self-nanoemulsifying drug delivery systems (SNEDDS) in different inflammatory diseases. It introduces the fundamental principles of SNEDDS, their formulation components, and characterization techniques, providing insights into their mechanisms of drug delivery and formulation optimization. The book also explores the potential of various combination therapies with SNEDDS, highlighting strategies, synergistic effects, and challenges. Furthermore, the chapters in the book highlight the applications of SNEDDS in specific inflammatory diseases, including diabetes, brain diseases, colorectal diseases, cardiovascular diseases, lung diseases, and cancer. Towards the end, the book evaluates the potential toxic effects of SNEDDS components and addresses safety considerations, regulatory aspects, patents, and clinical trials pertaining to SNEDDS. This book is intended for researchers, pharmacologists, pharmaceutical scientists, and clinicians involved in drug delivery and nanomedicine.

This book discusses the potential application of self-nanoemulsifying drug delivery systems (SNEDDS) in different inflammatory diseases. It introduces the fundamental principles of SNEDDS, their formulation components, and characterization techniques, providing insights into their mechanisms of drug delivery and formulation optimization. The book also explores the potential of various combination therapies with SNEDDS, highlighting strategies, synergistic effects, and challenges. Furthermore, the chapters in the book highlight the applications of SNEDDS in specific inflammatory diseases, including diabetes, brain diseases, colorectal diseases, cardiovascular diseases, lung diseases, and cancer. Towards the end, the book evaluates the potential toxic effects of SNEDDS components and addresses safety considerations, regulatory aspects, patents, and clinical trials pertaining to SNEDDS. This book is intended for researchers, pharmacologists, pharmaceutical scientists, and clinicians involved in drug delivery and nanomedicine.

This book presents the scientific as well as industrial perspectives, challenges, and advances in minimally invasive drug delivery systems for topical applications. It also covers the regulatory requirements and specifically discusses all the intellectual property rights filed and granted throughout the globe for minimally invasive systems.

This book presents detailed analyses of various minimally invasive drug delivery methods as well as the recent advances in devices such as microneedles, iontophoretic devices, probes, etc. This book will be of keen interest to a wide range of audiences, including clinical researchers working in the field of drug delivery and disease diagnosis, as well as undergraduate and postgraduate students from various disciplines such as pharmacy, pharmacology, pharmaceutics, biotechnology, and health sciences.

The book explores the intersection of nanotechnology and allergic airway diseases. With a focus on diagnosis and management, each chapter delves into specific areas of interest. Beginning with an introduction to the diseases, the book progresses to uncover the pathophysiology and immunology underlying allergic airway diseases. The epidemiology chapter provides insights into the prevalence and impact of these conditions. A significant portion of the book is dedicated to nanotechnology applications, with chapters on metal and metal oxide nanoparticles, nanomicelles, carbon nanotubes, liposomes, polymeric nanoparticles, solid lipid nanoparticles, dendrimers, nanofibers, and quantum dots. These chapters delve into the potential of these nanomaterials in managing allergic airway diseases, highlighting their unique properties, and promising therapeutic approaches. Finally, the book concludes with a chapter on future directions, exploring emerging trends and potential advancements in the field. This book will be a valuable resource for academics, caregivers, researchers, and industry professionals working in the field of airway allergic diseases. It includes translational and clinical researchers, under-graduates and postgraduates (Masters), PhDs, and post-doctoral researchers of various disciplines, including pharmaceutical sciences, biotechnology, immunology, and medical and health sciences.

This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery.