Navneet Sharma – författare

Chemoinformatics and Bioinformatics in the Pharmaceutical Sciences brings together two very important fields in pharmaceutical sciences that have been mostly seen as diverging from each other: chemoinformatics and bioinformatics. As developing drugs is an expensive and lengthy process, technology can improve the cost, efficiency and speed at which new drugs can be discovered and tested. This book presents some of the growing advancements of technology in the field of drug development and how the computational approaches explained here can reduce the financial and experimental burden of the drug discovery process.

This book will be useful to pharmaceutical science researchers and students who need basic knowledge of computational techniques relevant to their projects. Bioscientists, bioinformaticians, computational scientists, and other stakeholders from industry and academia will also find this book helpful.

Provides practical information on how to choose and use appropriate computational tools Presents the wide, intersecting fields of chemo-bio-informatics in an easily-accessible format Explores the fundamentals of the emerging field of chemoinformatics and bioinformatics

Fiber and Textile Engineering in Drug Delivery Systems explains how innovative textile processing methods including rotary spinning, microfluidics, wet spinning and electrospinning can be used to produce novel drug delivery solutions. This topical book provides detailed descriptions of how to produce such new materials for this purpose, with foundational content to help readers from a range of backgrounds understand the context of material selection and design decisions. Emphasis is given to the engineering side of the manufacturing of the textile and its role in drug delivery, but this also acts as a guide to pharmaceutical applications of textile fibers for materials scientists.

Drug delivery research is rapidly expanding and experimenting with new materials to drive improved clinical outcomes as the efficacy of the therapeutic molecule is highly dependent on the right choice of carrier system. Recently, fiber based carriers at both nano and micro scales are gaining interest in the scientific community due to ease of manufacturing, high surface area to volume ratio, desirable drug release kinetics and high mechanical strength.

Describes methods for material selection and design for drug delivery systems Provides case studies to explain how these techniques can be applied successfully Covers the regulatory and legal aspects of the use of the textiles and fibers in drug delivery

Computational Biology for Stem Cell Research seamlessly bridges the gap between the worlds of biomedical sciences and in silico computational methods. This book serves as a valuable resource for researchers and students, enabling them to grasp and delve into the intricacies of hematopoietic Stem Cells (HSCs) and mesenchymal Stem Cells (MSCs) through the lens of computational biology. This perspective sheds light on stem cell transplantation, translational research, and unique properties of stem cells like self-renewal and differentiation. In addition to introducing readers to stem cell-focused bioinformatics tools, this resource offers a clear pathway for effortlessly merging in silico methods with traditional in vitro and in vivo approaches.

Computational Biology for Stem Cell Research combines science and technology to showcase how computational methods transform stem cell research by reducing costs and enhancing investigations. The chapters uncover various approaches, from machine learning to genome analysis, for studying networks, protein interactions, dynamics, and the preprocessing of large datasets. The book aims to give readers a broad view of the advanced computational tools and methods extensively employed in stem cell research. Additionally, the book emphasizes the ongoing studies and tools yet to be developed for furthering stem cell research.

Modeling Stem Cell Behavior: Explore stem cell behavior through animal models, bridging laboratory studies to real-world clinical allogeneic HSC transplantation (HSCT) scenarios.Bioinformatics-Driven Translational Research: Navigate a path from bench to bedside with cutting-edge bioinformatics approaches, translating computational insights into tangible advancements in stem cell research and medical applications.Interdisciplinary Resource: Discover a single comprehensive resource catering to biomedical sciences, life sciences, and chemistry fields, offering essential insights into computational tools vital for modern research.

Bioresorbable Materials and Bioactive Surface Coatings: Biomedical Implants and Tissue Regeneration provides a detailed review of biomaterials specially designed for use in biomedical implants, tissue repair, and regeneration. A wide range of resorbable materials are covered, including polymers, bioceramics, metallic alloys, and dissolvable electronics, as well as their properties, degradation kinetics, and potential clinical uses. The book also explores bioactive surface modifications, highlighting their importance in enhancing the functionality of bioresorbable materials.Various coatings and surface modifications are covered, such as bioactive ceramic coatings, biofunctional polymer coatings, and surface modifications for enhanced osseointegration, cardiovascular applications, and neural interfaces. Additionally, regulatory guidelines for bioresorbable medical devices, ethical considerations, and environmental implications are analyzed.Details the fabrication techniques, properties, applications, and challenges of each material and implant typeCovers a range of applications, including orthopedics, neural engineering, drug delivery, and cardiovascular implantsReviews the qualities and benefits of various bioresorbable and bioactive materials, such as polymers, alloys, ceramics, and composites

This unique resource provides a comprehensive guide to the evolving regulations and standards which govern the international pharmaceutical industry. Featuring clear explanations of the latest regulations, as well as insights and strategies to maintain compliance, the book covers the key principles of best-practice for laboratory research, manufacturing, and distribution. It also offers strategies to navigate the intricacies of different regulatory environments so that pharmaceutical companies can operate internationally, avoiding the potentially costly risk of violations. Detailed and holistic, the book is an essential resource to pharmaceutical researchers and manufacturers, as well as an important resource for students and scholars in the field.

This unique resource provides a comprehensive guide to the evolving regulations and standards which govern the international pharmaceutical industry. Featuring clear explanations of the latest regulations, as well as insights and strategies to maintain compliance, the book covers the key principles of best-practice for laboratory research, manufacturing, and distribution. It also offers strategies to navigate the intricacies of different regulatory environments so that pharmaceutical companies can operate internationally, avoiding the potentially costly risk of violations. Detailed and holistic, the book is an essential resource to pharmaceutical researchers and manufacturers, as well as an important resource for students and scholars in the field.

This book analyses the internalization of conflict in the minds of children living and growing up in the Kashmir valley, and its effect on their identity formation and Schooling. It integrates the socio-cultural, socio-political, geo-political, and psycho-social contexts to understand the unfolding of childhood amidst conflicts.This volume highlights the socio-cultural context, amidst which children live in Kashmir, which influences the way they look at, interpret, and give meaning to their everyday environment—be it rural, urban, peaceful, violent, or within or away from family. This forms a significant part of how children’s lives are negotiated in Kashmir. It deliberates upon the interplay between conflict, education, and identity during the childhood years, especially since the traditional education systems tend to neglect the experiences of children amidst conflict. It also explores how children imitate, observe, and reflect on the conflicts in their surroundings.The book will interest scholars and researchers from the departments of education, sociology, social work, political science, peace and conflict studies, and South Asian studies.

This book examines targeted drug delivery systems covering molecular targeting mechanisms, nanotechnology-based carriers, and controlled release technologies. The analysis includes liposomes, dendrimers, polymer-based systems, and encapsulation techniques for enhanced bioavailability and reduced toxicity, and also includes:Comprehensive examination of targeted drug delivery systems covering molecular targeting mechanisms, biological processes, and therapeutic strategy optimizationAnalysis of advanced nanotechnology-based drug carriers including liposomes, dendrimers, and polymer-based delivery systems for precision medicine applicationsInvestigation of encapsulation materials and techniques for controlled drug release with emphasis on bioavailability enhancement and systemic toxicity reductionAssessment of regulatory considerations and clinical trial methodologies for drug delivery system development and approval processesStudy of personalized medicine approaches through targeted delivery technologies and their impact on therapeutic outcomesThe case studies help demonstrate precision targeting strategies, therapeutic outcome improvements, and systematic approaches to drug formulation, making it an important reading for understanding modern pharmaceutical technologies and their role in advancing healthcare through targeted therapeutic interventions.This title has been co-published with Manakin Press. T&F does not sell or distribute the print editions in Bangladesh, Bhutan, India, Nepal, Pakistan, and Sri lanka.