Neeraj Verma – författare

This comprehensive volume presents the fascinating and diverse world of microbial secondary metabolites, exploring their biosynthesis, ecological roles, and wide-ranging applications in biotechnology, pharmacy, agriculture, and various other industries. The initial chapters provide a foundational overview of microbial secondary metabolites and their immense value. The subsequent chapters discuss microbial strain engineering, enzymatic pathways, and metagenomic approaches to unlock hidden biosynthetic potential. Emphasis has also been given to how these natural products contribute to sustainable development, including eco-friendly agricultural practices and stress alleviation in crops through plant–microbe interactions. The book further explores source-specific contributions, with dedicated chapters on bacterial, fungal, algal, and marine microbial metabolites. Innovative applications are also highlighted in various chapters with recent advancements in technologies such as microbial mycoherbicides for weed control, viral-derived metabolites, and the promise of marine microbial communities. Special attention has also been given to sustainable exploitation and the integration of these compounds into functional products and solutions for global challenges.This book serves as a valuable reference for researchers and students of microbiology, biotechnology, and environmental sciences.The editors would welcome the fruitful suggestions from the readers to be incorporated into future editions.

This comprehensive volume of Industrial Applications of Microbial Secondary Metabolites: Biotechnological and Commercial Applications offers an in-depth, research-driven overview of microbial secondary metabolites, emphasizing their biosynthesis, functional diversity, and cross-sectoral industrial relevance. All chapters are authored by domain experts. This volume provides a comprehensive examination of microbial secondary metabolites, elucidating their biosynthetic complexity, ecological significance, and translational potential across agricultural, pharmaceutical, industrial, and environmental domains. Secondary metabolites, distinct from primary metabolic products, represent a vast array of structurally diverse and biologically active compounds produced by microorganisms such as bacteria, fungi, and actinomycetes, often under specific environmental or stress-induced conditions. The book investigates their regulatory networks, gene clusters (e.g., PKS, NRPS, and hybrid pathways), and microbial genomics that underpin metabolite production and optimization through advanced metabolic engineering, synthetic biology, and omics-integrated biotechnological platforms.Early chapters explain the role of secondary metabolites in various industries, detailing current bioprocessing methods for large-scale fermentation, strain improvement strategies, and downstream processing for value-added compounds. The book transitions into agronomic applications, where microbial metabolites act as natural elicitors, phytostimulants, and rhizosphere modulators.Detailed case studies explore the functional role of secondary metabolites in inducing systemic acquired resistance (SAR) and induced systemic resistance (ISR), modulating phytohormone signaling (e.g., auxin, ethylene, jasmonic acid), and suppressing pathogenic fungi, bacteria, and nematodes through antagonistic metabolites such as lipopeptides, siderophores, VOCs, and antibiotics.The integration of microbial consortia and bioformulations for sustainable agriculture—including biofertilizers, seed biopriming, and advanced delivery systems—is covered with an emphasis on formulation stability, carrier matrices, and shelf-life enhancement.The chapters also cover human health applications, including novel antimicrobials, immunomodulatory agents, and nutraceutical compounds derived from Ganoderma and probiotic strains. Industrial sections discuss microbial pigments and fungal-derived dyes as alternatives to synthetic colorants with their physicochemical properties, scalability, and applications in food, pharmaceuticals, and textiles.Nanotechnology-enabled strategies for metabolite production and delivery, including nano-bioreactors, green nanomanufacturing processes, nanoformulations, and biosensors for agriculture and diagnostics have also been discussed.The book also covers future trends in biomanufacturing, emphasizing the need for integrated biorefineries, AI-driven strain design, and global harmonization of microbial product commercialization. The regulatory and commercial landscapes are also evaluated, including guidelines for GRAS status, intellectual property, biosafety considerations, and pathway standardization for scale-up.This book will serve as a valuable reference for researchers, microbiologists, biotechnologists, agricultural scientists, environmental professionals, and industrial stakeholders engaged in microbial biotechnology and allied fields. This compilation will not only support ongoing academic and industrial efforts but also inspire novel research directions.Constructive feedback and suggestions from valued readers are warmly welcomed and will be thoughtfully considered for inclusion in future editions, ensuring that the content remains current, relevant, and impactful.

This comprehensive volume presents the fascinating and diverse world of microbial secondary metabolites, exploring their biosynthesis, ecological roles, and wide-ranging applications in biotechnology, pharmacy, agriculture, and various other industries. The initial chapters provide a foundational overview of microbial secondary metabolites and their immense value. The subsequent chapters discuss microbial strain engineering, enzymatic pathways, and metagenomic approaches to unlock hidden biosynthetic potential. Emphasis has also been given to how these natural products contribute to sustainable development, including eco-friendly agricultural practices and stress alleviation in crops through plant-microbe interactions. The book further explores source-specific contributions, with dedicated chapters on bacterial, fungal, algal, and marine microbial metabolites. Innovative applications are also highlighted in various chapters with recent advancements in technologies such as microbial mycoherbicides for weed control, viral-derived metabolites, and the promise of marine microbial communities. Special attention has also been given to sustainable exploitation and the integration of these compounds into functional products and solutions for global challenges.This book serves as a valuable reference for researchers and students of microbiology, biotechnology, and environmental sciences.The editors would welcome the fruitful suggestions from the readers to be incorporated into future editions.

This comprehensive volume of Industrial Applications of Microbial Secondary Metabolites: Biotechnological and Commercial Applications offers an in-depth, research-driven overview of microbial secondary metabolites, emphasizing their biosynthesis, functional diversity, and cross-sectoral industrial relevance. All chapters are authored by domain experts. This volume provides a comprehensive examination of microbial secondary metabolites, elucidating their biosynthetic complexity, ecological significance, and translational potential across agricultural, pharmaceutical, industrial, and environmental domains. Secondary metabolites, distinct from primary metabolic products, represent a vast array of structurally diverse and biologically active compounds produced by microorganisms such as bacteria, fungi, and actinomycetes, often under specific environmental or stress-induced conditions. The book investigates their regulatory networks, gene clusters (e.g., PKS, NRPS, and hybrid pathways), and microbial genomics that underpin metabolite production and optimization through advanced metabolic engineering, synthetic biology, and omics-integrated biotechnological platforms.Early chapters explain the role of secondary metabolites in various industries, detailing current bioprocessing methods for large-scale fermentation, strain improvement strategies, and downstream processing for value-added compounds. The book transitions into agronomic applications, where microbial metabolites act as natural elicitors, phytostimulants, and rhizosphere modulators.Detailed case studies explore the functional role of secondary metabolites in inducing systemic acquired resistance (SAR) and induced systemic resistance (ISR), modulating phytohormone signaling (e.g., auxin, ethylene, jasmonic acid), and suppressing pathogenic fungi, bacteria, and nematodes through antagonistic metabolites such as lipopeptides, siderophores, VOCs, and antibiotics.The integration of microbial consortia and bioformulations for sustainable agriculture-including biofertilizers, seed biopriming, and advanced delivery systems-is covered with an emphasis on formulation stability, carrier matrices, and shelf-life enhancement.The chapters also cover human health applications, including novel antimicrobials, immunomodulatory agents, and nutraceutical compounds derived from Ganoderma and probiotic strains. Industrial sections discuss microbial pigments and fungal-derived dyes as alternatives to synthetic colorants with their physicochemical properties, scalability, and applications in food, pharmaceuticals, and textiles.Nanotechnology-enabled strategies for metabolite production and delivery, including nano-bioreactors, green nanomanufacturing processes, nanoformulations, and biosensors for agriculture and diagnostics have also been discussed.The book also covers future trends in biomanufacturing, emphasizing the need for integrated biorefineries, AI-driven strain design, and global harmonization of microbial product commercialization. The regulatory and commercial landscapes are also evaluated, including guidelines for GRAS status, intellectual property, biosafety considerations, and pathway standardization for scale-up.This book will serve as a valuable reference for researchers, microbiologists, biotechnologists, agricultural scientists, environmental professionals, and industrial stakeholders engaged in microbial biotechnology and allied fields. This compilation will not only support ongoing academic and industrial efforts but also inspire novel research directions.Constructive feedback and suggestions from valued readers are warmly welcomed and will be thoughtfully considered for inclusion in future editions, ensuring that the content remains current, relevant, and impactful.

This comprehensive volume presents the fascinating and diverse world of microbial secondary metabolites, exploring their biosynthesis, ecological roles, and wide-ranging applications in biotechnology, pharmacy, agriculture, and various other industries. The initial chapters provide a foundational overview of microbial secondary metabolites and their immense value. The subsequent chapters discuss microbial strain engineering, enzymatic pathways, and metagenomic approaches to unlock hidden biosynthetic potential. Emphasis has also been given to how these natural products contribute to sustainable development, including eco-friendly agricultural practices and stress alleviation in crops through plant-microbe interactions. The book further explores source-specific contributions, with dedicated chapters on bacterial, fungal, algal, and marine microbial metabolites. Innovative applications are also highlighted in various chapters with recent advancements in technologies such as microbial mycoherbicides for weed control, viral-derived metabolites, and the promise of marine microbial communities. Special attention has also been given to sustainable exploitation and the integration of these compounds into functional products and solutions for global challenges.This book serves as a valuable reference for researchers and students of microbiology, biotechnology, and environmental sciences.The editors would welcome the fruitful suggestions from the readers to be incorporated into future editions.

This comprehensive volume of Industrial Applications of Microbial Secondary Metabolites: Biotechnological and Commercial Applications offers an in-depth, research-driven overview of microbial secondary metabolites, emphasizing their biosynthesis, functional diversity, and cross-sectoral industrial relevance. All chapters are authored by domain experts. This volume provides a comprehensive examination of microbial secondary metabolites, elucidating their biosynthetic complexity, ecological significance, and translational potential across agricultural, pharmaceutical, industrial, and environmental domains. Secondary metabolites, distinct from primary metabolic products, represent a vast array of structurally diverse and biologically active compounds produced by microorganisms such as bacteria, fungi, and actinomycetes, often under specific environmental or stress-induced conditions. The book investigates their regulatory networks, gene clusters (e.g., PKS, NRPS, and hybrid pathways), and microbial genomics that underpin metabolite production and optimization through advanced metabolic engineering, synthetic biology, and omics-integrated biotechnological platforms.Early chapters explain the role of secondary metabolites in various industries, detailing current bioprocessing methods for large-scale fermentation, strain improvement strategies, and downstream processing for value-added compounds. The book transitions into agronomic applications, where microbial metabolites act as natural elicitors, phytostimulants, and rhizosphere modulators.Detailed case studies explore the functional role of secondary metabolites in inducing systemic acquired resistance (SAR) and induced systemic resistance (ISR), modulating phytohormone signaling (e.g., auxin, ethylene, jasmonic acid), and suppressing pathogenic fungi, bacteria, and nematodes through antagonistic metabolites such as lipopeptides, siderophores, VOCs, and antibiotics.The integration of microbial consortia and bioformulations for sustainable agriculture-including biofertilizers, seed biopriming, and advanced delivery systems-is covered with an emphasis on formulation stability, carrier matrices, and shelf-life enhancement.The chapters also cover human health applications, including novel antimicrobials, immunomodulatory agents, and nutraceutical compounds derived from Ganoderma and probiotic strains. Industrial sections discuss microbial pigments and fungal-derived dyes as alternatives to synthetic colorants with their physicochemical properties, scalability, and applications in food, pharmaceuticals, and textiles.Nanotechnology-enabled strategies for metabolite production and delivery, including nano-bioreactors, green nanomanufacturing processes, nanoformulations, and biosensors for agriculture and diagnostics have also been discussed.The book also covers future trends in biomanufacturing, emphasizing the need for integrated biorefineries, AI-driven strain design, and global harmonization of microbial product commercialization. The regulatory and commercial landscapes are also evaluated, including guidelines for GRAS status, intellectual property, biosafety considerations, and pathway standardization for scale-up.This book will serve as a valuable reference for researchers, microbiologists, biotechnologists, agricultural scientists, environmental professionals, and industrial stakeholders engaged in microbial biotechnology and allied fields. This compilation will not only support ongoing academic and industrial efforts but also inspire novel research directions.Constructive feedback and suggestions from valued readers are warmly welcomed and will be thoughtfully considered for inclusion in future editions, ensuring that the content remains current, relevant, and impactful.

Understanding and coding advanced deep learning algorithms with the most intuitive deep learning library in existenceKey FeaturesExplore the most advanced deep learning techniques that drive modern AI resultsImplement deep neural networks, autoencoders, GANs, VAEs, and deep reinforcement learningA wide study of GANs, including Improved GANs, Cross-Domain GANs, and Disentangled Representation GANsBook DescriptionRecent developments in deep learning, including Generative Adversarial Networks (GANs), Variational Autoencoders (VAEs), and Deep Reinforcement Learning (DRL) are creating impressive AI results in our news headlines - such as AlphaGo Zero beating world chess champions, and generative AI that can create art paintings that sell for over $400k because they are so human-like.Advanced Deep Learning with Keras is a comprehensive guide to the advanced deep learning techniques available today, so you can create your own cutting-edge AI. Using Keras as an open-source deep learning library, you'll find hands-on projects throughout that show you how to create more effective AI with the latest techniques.The journey begins with an overview of MLPs, CNNs, and RNNs, which are the building blocks for the more advanced techniques in the book. You’ll learn how to implement deep learning models with Keras and TensorFlow 1.x, and move forwards to advanced techniques, as you explore deep neural network architectures, including ResNet and DenseNet, and how to create autoencoders. You then learn all about GANs, and how they can open new levels of AI performance. Next, you’ll get up to speed with how VAEs are implemented, and you’ll see how GANs and VAEs have the generative power to synthesize data that can be extremely convincing to humans - a major stride forward for modern AI. To complete this set of advanced techniques, you'll learn how to implement DRL such as Deep Q-Learning and Policy Gradient Methods, which are critical to many modern results in AI.What you will learnCutting-edge techniques in human-like AI performanceImplement advanced deep learning models using KerasThe building blocks for advanced techniques - MLPs, CNNs, and RNNsDeep neural networks – ResNet and DenseNetAutoencoders and Variational Autoencoders (VAEs)Generative Adversarial Networks (GANs) and creative AI techniquesDisentangled Representation GANs, and Cross-Domain GANsDeep reinforcement learning methods and implementationProduce industry-standard applications using OpenAI GymDeep Q-Learning and Policy Gradient MethodsWho this book is forSome fluency with Python is assumed. As an advanced book, you'll be familiar with some machine learning approaches, and some practical experience with DL will be helpful. Knowledge of Keras or TensorFlow 1.x is not required but would be helpful.

Nanofertilizers and nanopesticides increase crop efficiency because of a several-fold increase in the surface-to-volume ratio of nano-forms of nutrients and their suitability to foliar application. The potential agricultural benefits of these nanomaterials, their modes of action, and the fate of nanomaterials in the soil are all discussed. This book uses a multidisciplinary approach and highlights the expertise of the authors in the fields of materials science, nanotechnology, nanobiosensors, and agricultural research. It describes the details of nanoscale synthesis of materials for targeted delivery; in vitro, in vivo, and field trials experimentation; how to use digital technology for specific solutions including Big Data to create predictive mathematical modelling; along with the core knowledge of plant systems and their biosphere to improve crop yields. Also, the book discusses future perspectives and challenges of nanomaterials in agricultural applications.In summary, this book discusses agricultural nanobiotechnology with its main emphasis on understanding the interactions of nanoscale materials of pesticides and fertilizers. It also covers their application to improve the quality and increase crop yield with a minimum use of the active ingredients attached to the nanocarriers.

Nanofertilizers and nanopesticides increase crop efficiency because of a several-fold increase in the surface-to-volume ratio of nano-forms of nutrients and their suitability to foliar application. The potential agricultural benefits of these nanomaterials, their modes of action, and the fate of nanomaterials in the soil are all discussed. This book uses a multidisciplinary approach and highlights the expertise of the authors in the fields of materials science, nanotechnology, nanobiosensors, and agricultural research. It describes the details of nanoscale synthesis of materials for targeted delivery; in vitro, in vivo, and field trials experimentation; how to use digital technology for specific solutions including Big Data to create predictive mathematical modelling; along with the core knowledge of plant systems and their biosphere to improve crop yields. Also, the book discusses future perspectives and challenges of nanomaterials in agricultural applications.In summary, this book discusses agricultural nanobiotechnology with its main emphasis on understanding the interactions of nanoscale materials of pesticides and fertilizers. It also covers their application to improve the quality and increase crop yield with a minimum use of the active ingredients attached to the nanocarriers.