Patrick Clarysse – författare

Biomechanics of the Heart: From Model to Patient provides readers with a comprehensive overview of the modeling and assessment of the heart’s biomechanics. The book addresses topics such as the physiology of normal and diseased hearts, cardiovascular imaging, modeling of myocardial tissue in the passive and active states, as well as state-of-the-art approaches for patient specific modeling of the heart’s mechanical function. This is all augmented by case studies and examples of exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases. Readers are introduced to modeling of the heart’s anatomical and muscular structure, a review of imaging techniques to analyze the geometry, content and dynamics of the heart, as well as an in-depth look at the biomechanical properties of normal and diseased hearts. Finally, chapters cover modeling cardiac passive and contractile mechanics, biomechanical finite element simulations of the heart, patient-specific modeling of the heart and circulatory system, as well as the exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases.Focuses on the imaging and modeling of the heart’s biomechanicsPresents all the components necessary to build realistic cardiac models tailored to individual health assessment as well as for broader clinical researchExplores computer-aided diagnosis, treatment, and monitoring of heart diseases

The imaging of moving organs such as the heart, in particular, is a real challenge because of its movement. This book presents current and emerging methods developed for the acquisition of images of moving organs in the five main medical imaging modalities: conventional X-rays, computed tomography (CT), magnetic resonance imaging (MRI), nuclear imaging and ultrasound. The availability of dynamic image sequences allows for the qualitative and quantitative assessment of an organ’s dynamics, which is often linked to pathologies.

This book constitutes the refereed proceedings of the 12th International Conference on Functional Imaging and Modeling of the Heart, held in Lyon, France, in June 2023.The 72 full papers were carefully reviewed and selected from 80 submissions. The focus of the papers is on following topics: increased imaging resolutions, data explosion, sophistication of computational models and advent of AI frameworks, while new imaging modalities have emerged (e.g. combined PET-MRI, Spectral CT).

This book constitutes the refereed proceedings of the 12th International Conference on Functional Imaging and Modeling of the Heart, held in Lyon, France, in June 2023.

The 72 full papers were carefully reviewed and selected from 80 submissions. The focus of the papers is on following topics: increased imaging resolutions, data explosion, sophistication of computational models and advent of AI frameworks, while new imaging modalities have emerged (e.g. combined PET-MRI, Spectral CT).

The ?rst international conference on Functional Imaging and Modeling of the 1 Heart (FIMH) was held in Helsinki, Finland, in November 2001, thanks to the strongscienti?ccollaborationbetweenFranceandFinland. Thiseventwasa?rst attempt to federate the heart imaging community and to encourage collabo- tion between scientists in signal and image processing, applied mathematics and physics, biomedical engineering and computer science, and experts in card- logy, radiology, biology, and physiology, in Europe and beyond. The conference has encountered considerable success. The outstanding research works pres- ted have demonstrated a very active research ?eld with complex modeling and image analysis problems to be solved. One of the outcomes was the special issue of the Medical Image Analysis journal based on a selection of the conference’s best papers, to appear in the second half of 2003. The FIMH 2001 meeting was the starting point of a discussion for federating the European research e?ort in cardiac imaging, heart modeling, and cardiac image analysis. It was very successful, and a large coalition was created around 2 the e-Heart proposal for a Network of Excellence in the European Sixth Fra- work Program. The e-Heart network has already gathered about 200 researchers from 100 institutes. A project proposal has been submitted to the European Union. It was decided in the ?rst meeting to organize a regular biennial conference.

Therecentdevelopmentsindynamiccardiacimagingandmodelingarethe- sultofanincreasinglyfruitfulcooperationbetweentheoreticians,engineers,and practitioners. Thestandardclinicalparametersareprogressivelybene?ttingfrom moreaccuratequantitativemeasurementsthankstoasimultaneoususeof- phisticateddataacquisitiontechniquessuchasmultichannelECGandMEG, dynamicUS,doppler,X-Ray,CT,helicalCT,MRI,fMRI,SPECT,PET...data andadvancedphysicalandmathematicaltools. Itisbecomingpossibleto- cientlycombineprioranatomicalandfunctionalknowledgewithadvanced3D spatio-temporaldigitaldata. Thechallengenowisclearlytocorrelatethemicro structureandfunctionoftheorganfromthecellularlevelwithitsmacroscopic functionalbehavior. TheFIMH2001internationalworkshopaimedtopromotecollaborationb- weenscientistsinsignalandimageprocessing,appliedmathematicsandphysics, biomedicalengineeringandcomputerscience,andexpertsincardiology,rad- logy,biology,andphysiology. TheFIMH2001workshop,inits?rstyear,focused oncomplexheartmodelsinvolvinganatomicalandfunctionalinformation. The goalistograduallymovetowardhybrid3Dbiomechanicalandelectrophysio- gicalmodelsabletosimulatethedynamicbehavioroftheheart.WefeelthatFIMH2001presentedanopportunitytocreateacardio-vascular researchnetworkataEuropeanleveltofederatethemainpluridisciplinary groupsinvolvedinadvancedresearchincardiovascularimagingandmodeling inEurope. Theideaistocreatewhatcouldbecalledthe"EuropeanBeating HeartProject". Thepurposeofsuchaprojectistojoinresearche?ortsto- provediagnosisandtherapyofpathologicaldysfunctionsoftheheart,forthe bene?tofthepatient,throughfundamentalandclinicalresearch. September2001 ToivoKatila IsabelleE. Magnin VI Preface Acknowledgements Themembersoftheprogramcommitteedeservespecialthanksfortheirjob inreviewingallthepapers,andfortheirsupportintheorganizationofthe conference. WethankthemembersoftheCREATISunitinLyonandtheLaboratory ofBiomedicalEngineeringinHelsinkifortheirinvolvementandsupportinthe organizationofthisconference. Conferencesupportedby InstitutNationaldesSciencesAppliqu'eesdeLyon(INSA),France HelsinkiUniversityofTechnology(HUT),Finland CentreNationaldelaRechercheScienti?que(CNRS),France ScienceAcademyofFinland Jointincentiveaction"BeatingHeart"oftheCNRS,France FrenchCulturalCenter,Helsinki French-FinnishAssociationforScienti?candTechnicalResearch(AFFRST) FrenchBiomedicalEngineeringSociety(SFGBM) Organization FIMH2001wasco-organizedbytheCREATISLaboratory,CNRSUMR5515, Lyon,France,andtheLaboratoryofBiomedicalEngineeringattheHelsinski UniversityofTechnology,Finland.ConferenceChairs ToivoKatila LaboratoryofBiomedicalEngineering,H- sinskiUniversityofTechnology,Finland IsabelleE. Magnin CREATIS,CNRSUMR5515,Lyon,France OrganizationCommittee PatrickClarysse CREATIS,CNRSUMR5515,Lyon,France JohanMontagnat CREATIS,CNRSUMR5515,Lyon,France JukkaNenonen LaboratoryofBiomedicalEngineering,H- sinskiUniversityofTechnology,Finland ProgramCommittee T. Arts UniversityofTechnologyofEindhoven,The Netherlands N. Ayache INRIASophia-Antipolis,France S. Baillet LaPiti'eSalp'etri'ere,Paris,France M. Barlaud I3S,Sophia-Antipolis,France L. Bidaut HopitauxUniversitairesdeGen'eve,Switz- land B. Bijnens MIC,KatholiekeUniversiteitLeuven,Belgium I. Bloch ENST,Paris,France E. Canet CREATIS,Lyon,France P. Clarysse CREATIS,Lyon,France L. Cohen CEREMADE,Paris,France P. Croisille CREATIS,Lyon,France J. Declerck OMIA,Oxford,UnitedKingdom H. Delingette INRIASophia-Antipolis,France J. D'hooge MIC,KatholiekeUniversiteitLeuven,Belgium R. Fenici CatholicUniversityofRome,Italy D. Friboulet CREATIS,Lyon,France A. Herment INSERMU494,Paris,France M. Horacek DalhousieUniversity,Canada M. Janier CREATIS,Lyon,France H. Larson HvidovreHospital,Denmark K.Lauerma HelsinkiUniversityCentralHospital,Finland VIII Organization ProgramCommittee(continuation) S. Loncaric UniversityofZagreb,Croatia J. L..otj..onen VTTTechnology,Tampere,Finland I. E. Magnin CREATIS,Lyon,France M. M.. akij..arvi HelsinkiUniversityCentralHospital,Helsinki, Finland J. Meunier Universit'edeMontr'eal,Canada J. Montagnat CREATIS,Lyon,France P. Nekkola UniversityofTechnology,Munich,Germany J. Nenonen HelsinkiUniversityofTechnology,Finland A. Noble MedicalVisionLaboratory,Oxford, UnitedKingdom J. Ohayon Universit'edeSavoie,France M. Orkisz CREATIS,Lyon,France N. Rougon ARTEMIS,InstitutNationaldes T'el'ecommunicationd'Evry,France C. Roux ENSTBretagne,France P. Rubel INSERMU121,Lyon,France F. Sachse UniversityofKarlsruhe,Germany J. Sequeira LIM,Marseille,France G. Sutherland MIC,KatholiekeUniversiteitLeuven,Belgium B. Tilg UniversityofGraz,Austria Y. Usson TIMC,Grenoble,France Y. -M. Zhu CREATIS,Lyon,France TableofContents InvitedSpeaker ModulesinCardiacModeling:Mechanics,Circulation, andDepolarizationWave ...1 T. Arts,P. Bovendeerd,A. vanderToorn,L. Geerts,R. Kerckho?s, F. Prinzen Session1:AnatomicalModeling GeometricalModelingoftheHeartandItsMainVessels ...10 J. -L.Mari,L. Astart,J. Sequeira Reconstructing3DBoundaryElementHeartModels from2DBiplaneFluoroscopy...17 H. Veister..a,J. L..otj..onen IntroducingSpectralEstimationforBoundaryDetection inEchographicRadiofrequencyImages ...24 I. Dydenko,D. Friboulet,I. E. Magnin GeometricalModellingoftheFibreOrganization intheHumanLeftVentricle...

The ?rst international conference on Functional Imaging and Modeling of the 1 Heart (FIMH) was held in Helsinki, Finland, in November 2001, thanks to the strongscienti?ccollaborationbetweenFranceandFinland. Thiseventwasa?rst attempt to federate the heart imaging community and to encourage collabo- tion between scientists in signal and image processing, applied mathematics and physics, biomedical engineering and computer science, and experts in card- logy, radiology, biology, and physiology, in Europe and beyond. The conference has encountered considerable success. The outstanding research works pres- ted have demonstrated a very active research ?eld with complex modeling and image analysis problems to be solved. One of the outcomes was the special issue of the Medical Image Analysis journal based on a selection of the conference’s best papers, to appear in the second half of 2003. The FIMH 2001 meeting was the starting point of a discussion for federating the European research e?ort in cardiac imaging, heart modeling, and cardiac image analysis. It was very successful, and a large coalition was created around 2 the e-Heart proposal for a Network of Excellence in the European Sixth Fra- work Program. The e-Heart network has already gathered about 200 researchers from 100 institutes. A project proposal has been submitted to the European Union. It was decided in the ?rst meeting to organize a regular biennial conference.