Peter Muller - Böcker

Crystal Structure Refinement is a mixture of textbook and tutorial. As A Crystallographers Guide to SHELXL it covers advanced aspects of practical crystal structure refinement, which have not been much addressed by textbooks so far. After an introduction to SHELXL in the first chapter, a brief survey of crystal structure refinement is provided. Chapters three and higher address the various aspects of structure refinement, from the treatment of hydrogen atoms to the assignment of atom types, to disorder, to non-crystallographic symmetry and twinning. One chapter is dedicated to the refinement of macromolecular structures and two short chapters deal with structure validation (one for small molecule structures and one for macromolecules). In each of the chapters the book gives refinement examples, based on the program SHELXL, describing every problem in detail. It comes with a CD-ROM with all files necessary to reproduce the refinements.

This volume provides a thorough introduction and reference for any researcher who is interested in Bayesian inference for wavelet-based models, but is not necessarily an expert in either. To achieve this goal the book starts with an extensive introductory chapter providing a self-contained introduction to the use of wavelet decompositions and the relation to Bayesian inference. The remaining papers in this volume are divided into six parts: independent prior modeling; decision theoretic aspects; dependent prior modeling; spatial models using bivariate wavelet bases; empirical Bayes approaches; and case studies. Chapters are written by experts who published the original research papers establishing the use of wavelet-based models in Bayesian inference. Peter Muller is Associate Professor and Brani Vidakovic is Assistant Professor of Statistics at Duke University.

WiMAX is the first standard technology to deliver true broadband mobility at speeds that enable powerful multimedia applications such as Voice over Internet Protocol (VoIP), online gaming, mobile TV, and personalized infotainment. WiMAX Security and Quality of Service, focuses on the interdisciplinary subject of advanced Security and Quality of Service (QoS) in WiMAX wireless telecommunication systems including its models, standards, implementations, and applications. Split into 4 parts, Part A of the book is an end-to-end overview of the WiMAX architecture, protocol, and system requirements. Security is an essential element in the wireless world and Part B is fully dedicated to this topic. Part C provides an in depth analysis of QoS, including mobility management in WiMAX. Finally, Part D introduces the reader to advanced and future topics. One of the first texts to cover security, QoS and deployments of WiMAX in the same book.Introduces the primary concepts of the interdisciplinary nature of WiMAX security and QoS, and also includes discussion of hot topics in the field.Written for engineers and researchers, answering practical questions from industry and the experimental field in academia.Explains how WiMAX applications’ security and QoS are interconnected and interworked among the cross layers.

The entertainment business is a most democratic field, offering success to anyone who has the talent, ability, and drive to master their art. But in order to achieve this goal, an individual must also possess knowledge, particularly in the area of contracts and agreements. This work represents a comprehensive overview of the procedures, timing, and agreements used in the motion picture, television, and video industries, and provides model contracts and explanations as to why specific clauses are employed and what the mutual benefits of each may be.The work presents the major contracts utilized in the show business industry in a manner that is readable and understandable to artists, producers, writers, directors, and other members of the entertainment community. Peter Muller breaks the contracts down to their essential elements, and offers detailed accounts of their legal implications for both parties involved. Among the contracts and agreements examined are the personal manager, agent, actor, director, and screen writer agreements; the motion picture distribution agreement; pay-per-view; licensing feature films for television syndication; international coproductions; home video license agreements; endorsements; and independent production financing. This hands-on guide to show business law will prove to be a valuable addition to public, academic, and law libraries, as well as a useful reference tool for literary and talent agencies, entertainment companies, and individuals in the entertainment industry.

Muller's work is designed to provide a comprehensive introduction to the major agreements prevalent in the recording and music entertainment industry today. Muller begins with the basics of the personal management and agency agreement and then examines the types of agreements a successful musician/group would encounter: recording and performance rights, film, commercials, tours, and personal appearances. Examples of the agreement forms currently being used are provided in an appendix. The book concludes with a bibliography and general subject index.

Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer’s disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adaptive Methods for Clinical Trials explores the growing role of Bayesian thinking in the rapidly changing world of clinical trial analysis.The book first summarizes the current state of clinical trial design and analysis and introduces the main ideas and potential benefits of a Bayesian alternative. It then gives an overview of basic Bayesian methodological and computational tools needed for Bayesian clinical trials. With a focus on Bayesian designs that achieve good power and Type I error, the next chapters present Bayesian tools useful in early (Phase I) and middle (Phase II) clinical trials as well as two recent Bayesian adaptive Phase II studies: the BATTLE and ISPY-2 trials. In the following chapter on late (Phase III) studies, the authors emphasize modern adaptive methods and seamless Phase II–III trials for maximizing information usage and minimizing trial duration. They also describe a case study of a recently approved medical device to treat atrial fibrillation. The concluding chapter covers key special topics, such as the proper use of historical data, equivalence studies, and subgroup analysis.For readers involved in clinical trials research, this book significantly updates and expands their statistical toolkits. The authors provide many detailed examples drawing on real data sets. The R and WinBUGS codes used throughout are available on supporting websites.Scott Berry talks about the book on the CRC Press YouTube Channel.

Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer’s disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adaptive Methods for Clinical Trials explores the growing role of Bayesian thinking in the rapidly changing world of clinical trial analysis.The book first summarizes the current state of clinical trial design and analysis and introduces the main ideas and potential benefits of a Bayesian alternative. It then gives an overview of basic Bayesian methodological and computational tools needed for Bayesian clinical trials. With a focus on Bayesian designs that achieve good power and Type I error, the next chapters present Bayesian tools useful in early (Phase I) and middle (Phase II) clinical trials as well as two recent Bayesian adaptive Phase II studies: the BATTLE and ISPY-2 trials. In the following chapter on late (Phase III) studies, the authors emphasize modern adaptive methods and seamless Phase II–III trials for maximizing information usage and minimizing trial duration. They also describe a case study of a recently approved medical device to treat atrial fibrillation. The concluding chapter covers key special topics, such as the proper use of historical data, equivalence studies, and subgroup analysis.For readers involved in clinical trials research, this book significantly updates and expands their statistical toolkits. The authors provide many detailed examples drawing on real data sets. The R and WinBUGS codes used throughout are available on supporting websites.Scott Berry talks about the book on the CRC Press YouTube Channel.

Research in Bayesian analysis and statistical decision theory is rapidly expanding and diversifying, making it increasingly more difficult for any single researcher to stay up to date on all current research frontiers. This book provides a review of current research challenges and opportunities. While the book can not exhaustively cover all current research areas, it does include some exemplary discussion of most research frontiers. Topics include objective Bayesian inference, shrinkage estimation and other decision based estimation, model selection and testing, nonparametric Bayes, the interface of Bayesian and frequentist inference, data mining and machine learning, methods for categorical and spatio-temporal data analysis and posterior simulation methods. Several major application areas are covered: computer models, Bayesian clinical trial design, epidemiology, phylogenetics, bioinformatics, climate modeling and applications in political science, finance and marketing. As a review of current research in Bayesian analysis the book presents a balance between theory and applications. The lack of a clear demarcation between theoretical and applied research is a reflection of the highly interdisciplinary and often applied nature of research in Bayesian statistics. The book is intended as an update for researchers in Bayesian statistics, including non-statisticians who make use of Bayesian inference to address substantive research questions in other fields. It would also be useful for graduate students and research scholars in statistics or biostatistics who wish to acquaint themselves with current research frontiers.

The study of the ocean is almost as old as the history of mankind itself. When the first seafarers set out in their primitive ships they had to understand, as best they could, tides and currents, eddies and vortices, for lack of understanding often led to loss of live. These primitive oceanographers were, of course, primarily statisticians. They collected what empirical data they could, and passed it down, ini­ tially by word of mouth, to their descendants. Data collection continued throughout the millenia, and although data bases became larger, more re­ liable, and better codified, it was not really until surprisingly recently that mankind began to try to understand the physics behind these data, and, shortly afterwards, to attempt to model it. The basic modelling tool of physical oceanography is, today, the partial differential equation. Somehow, we all 'know" that if only we could find the right set of equations, with the right initial and boundary conditions, then we could solve the mysteries of ocean dynamics once and for all.

Research in Bayesian analysis and statistical decision theory is rapidly expanding and diversifying, making it increasingly more difficult for any single researcher to stay up to date on all current research frontiers. This book provides a review of current research challenges and opportunities. While the book can not exhaustively cover all current research areas, it does include some exemplary discussion of most research frontiers. Topics include objective Bayesian inference, shrinkage estimation and other decision based estimation, model selection and testing, nonparametric Bayes, the interface of Bayesian and frequentist inference, data mining and machine learning, methods for categorical and spatio-temporal data analysis and posterior simulation methods. Several major application areas are covered: computer models, Bayesian clinical trial design, epidemiology, phylogenetics, bioinformatics, climate modeling and applications in political science, finance and marketing. As a review of current research in Bayesian analysis the book presents a balance between theory and applications. The lack of a clear demarcation between theoretical and applied research is a reflection of the highly interdisciplinary and often applied nature of research in Bayesian statistics. The book is intended as an update for researchers in Bayesian statistics, including non-statisticians who make use of Bayesian inference to address substantive research questions in other fields. It would also be useful for graduate students and research scholars in statistics or biostatistics who wish to acquaint themselves with current research frontiers.

Every year, some 200,000 people set out on the world's most famous pilgrimage route - 'the Camino', designated a World Heritage Site in 1993. Actually a network of paths with numerous starting places in France and throughout Europe, all routes converge to lead along Spain's northern coast to Santiago de Compostela. Here the shrine of St James, the patron saint of pilgrimage, was discovered in the 9th century. Already the preferred guide for German and Spanish pilgrims, this new English edition is co-published with the Confraternity of St James, the UK's leading organisation for promoting pilgrimage to Santiago. A mix of practical information and spiritual inspiration for walkers, it offers a stage-by-stage guide pointing out places of interest along the way; practical tips for walkers; prayers, blessings and spiritual exercises to nourish the pilgrim spirit and deepen the pilgrimage experience. It is illustrated throughout with maps and photographs, and conveniently pocket sized.

This book presents a collection of research papers that address the challenge of how to develop software in a principled way that, in particular, enables reasoning. The individual papers approach this challenge from various perspectives including programming languages, program verification, and the systematic variation of software. Topics covered include programming abstractions for concurrent and distributed software, specification and verification techniques for imperative programs, and development techniques for software product lines.With this book the editors and authors wish to acknowledge – on the occasion of his 60th birthday – the work of Arnd Poetzsch-Heffter, who has made major contributions to software technology throughout his career. It features articles on Arnd’s broad research interests including, among others, the implementation of programming languages, formal semantics, specification and verification of object-oriented and concurrent programs, programming language design, distributed systems, software modeling, and software product lines. All contributing authors are leading experts in programming languages and software engineering who have collaborated with Arnd in the course of his career.Overall, the book offers a collection of high-quality articles, presenting original research results, major case studies, and inspiring visions. Some of the work included here was presented at a symposium in honor of Arnd Poetzsch-Heffter, held in Kaiserslautern, Germany, in November 2018.

This open access book constitutes the proceedings of the 29th European Symposium on Programming, ESOP 2020, which was planned to take place in Dublin, Ireland, in April 2020, as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2020.

Our time is characterized by an explosive growth in the use of ever more complicated and sophisticated (computer) models. These models rely on dynamical systems theory for the interpretation of their results and on probability theory for the quantification of their uncertainties. A conscientious and intelligent use of these models requires that both these theories are properly understood.This book is to provide such understanding. It gives a unifying treatment of dynamical systems theory and probability theory. It covers the basic concepts and statements of these theories, their interrelations, and their applications to scientific reasoning and physics. The book stresses the underlying concepts and mathematical structures but is written in a simple and illuminating manner without sacrificing too much mathematical rigor.The book is aimed at students, post-docs, and researchers in the applied sciences who aspire to better understand the conceptual and mathematical underpinnings of the models that they use. Despite the peculiarities of any applied science, dynamics and probability are the common and indispensable tools in any modeling effort. The book is self-contained, with many technical aspects covered in appendices, but does require some basic knowledge in analysis, linear algebra, and physics.Peter Müller, now a professor emeritus at the University of Hawaii, has worked extensively on ocean and climate models and the foundations of complex system theories.

Our time is characterized by an explosive growth in the use of ever more complicated and sophisticated (computer) models. These models rely on dynamical systems theory for the interpretation of their results and on probability theory for the quantification of their uncertainties. A conscientious and intelligent use of these models requires that both these theories are properly understood.This book is to provide such understanding. It gives a unifying treatment of dynamical systems theory and probability theory. It covers the basic concepts and statements of these theories, their interrelations, and their applications to scientific reasoning and physics. The book stresses the underlying concepts and mathematical structures but is written in a simple and illuminating manner without sacrificing too much mathematical rigor.The book is aimed at students, post-docs, and researchers in the applied sciences who aspire to better understand the conceptual and mathematical underpinnings of the models that they use. Despite the peculiarities of any applied science, dynamics and probability are the common and indispensable tools in any modeling effort. The book is self-contained, with many technical aspects covered in appendices, but does require some basic knowledge in analysis, linear algebra, and physics.Peter Müller, now a professor emeritus at the University of Hawaii, has worked extensively on ocean and climate models and the foundations of complex system theories.

When the SCION project started in 2009, the goal was to create an architecture offering high availability and security for basic point-to-point communication. In the five years since the publication of SCION: A Secure Internet Architecture, this next-generation Internet architecture has evolved in terms of both design and deployment.On the one hand, there has been development of exciting new concepts and systems, including a new global time-synchronization system, an inter-domain approach for bandwidth reservations called COLIBRI, and Green Networking, which allows combating global climate change on three fronts. On the other hand, SCION is now also in production use by the Swiss financial ecosystem, and enables participants such as the Swiss National Bank, the Swiss provider of clearing services (SIX), and all Swiss financial institutes to communicate securely and reliably with each other via the Secure Swiss Finance Network.This unique guidebook provides an updated description of SCION's main components, covering new research topics and the most recent deployments. In particular, it presents in-depth discussion of formal verification efforts. Importantly, it offers a comprehensive, thorough description of the current SCION system:Describes the principles that guided SCION's design as a secure and robust Internet architectureProvides a comprehensive description of the next evolution in the way data finds its way through the InternetExplains how SCION can contribute to reducing carbon emissions, by introducing SCION Green NetworkingDemonstrates how SCION not only functions in academic settings but also works in production deploymentsDiscusses additional use cases for driving SCION's adoptionPresents the approaches for formal verification of protocols and codeIllustrated with many colorful figures, pictures, and diagrams, allowing easy access to the concepts and use cases Assembled by a team with extensive experience in the fields of computer networks and security, this text/reference is suitable for researchers, practitioners, and graduate students interested in network security. Also, readers with limited background in computer networking but with a desire to know more about SCION will benefit from an overview of relevant chapters in the beginning of the book.

When the SCION project started in 2009, the goal was to create an architecture offering high availability and security for basic point-to-point communication. In the five years since the publication of SCION: A Secure Internet Architecture, this next-generation Internet architecture has evolved in terms of both design and deployment.On the one hand, there has been development of exciting new concepts and systems, including a new global time-synchronization system, an inter-domain approach for bandwidth reservations called COLIBRI, and Green Networking, which allows combating global climate change on three fronts. On the other hand, SCION is now also in production use by the Swiss financial ecosystem, and enables participants such as the Swiss National Bank, the Swiss provider of clearing services (SIX), and all Swiss financial institutes to communicate securely and reliably with each other via the Secure Swiss Finance Network.This unique guidebook provides an updated description of SCION's main components, covering new research topics and the most recent deployments. In particular, it presents in-depth discussion of formal verification efforts. Importantly, it offers a comprehensive, thorough description of the current SCION system:Describes the principles that guided SCION's design as a secure and robust Internet architectureProvides a comprehensive description of the next evolution in the way data finds its way through the InternetExplains how SCION can contribute to reducing carbon emissions, by introducing SCION Green NetworkingDemonstrates how SCION not only functions in academic settings but also works in production deploymentsDiscusses additional use cases for driving SCION's adoptionPresents the approaches for formal verification of protocols and codeIllustrated with many colorful figures, pictures, and diagrams, allowing easy access to the concepts and use cases Assembled by a team with extensive experience in the fields of computer networks and security, this text/reference is suitable for researchers, practitioners, and graduate students interested in network security. Also, readers with limited background in computer networking but with a desire to know more about SCION will benefit from an overview of relevant chapters in the beginning of the book.