Robert Langer – författare

The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field.Key Features* Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves* Essential to anyone working in the field* Educates and directs both the novice and advanced researcher* Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves* Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell* Considered the definitive reference in the field* List of contributors reads like a "who''s who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

First published in 1997, Principles of Tissue Engineering is the widely recognized definitive resource in the field. The third edition provides a much needed update of the rapid progress that has been achieved in the field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world''s experts of what is currently known about each specific organ system. This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike.New to this edition:*Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves*Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems

Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world''s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future.This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike.- Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves- Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems- Full-color presentation throughout

Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world's experts of what is currently known about each specific organ system.

As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future.

This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production - is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.

Organized into twenty-three parts, covering the basics of tissue growth and development, approaches to tissue and organ design, and a summary of current knowledge by organ system Introduces a new section and chapters on emerging technologies in the field Full-color presentation throughout

Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world''s experts of what is currently known about each specific organ system.As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future.This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.- Organized into twenty-three parts, covering the basics of tissue growth and development, approaches to tissue and organ design, and a summary of current knowledge by organ system- Introduces a new section and chapters on emerging technologies in the field- Full-color presentation throughout

This volume examines transmission processes of Alevi religious knowledge and ritual practice in the last decades. It assembles contributions by researchers from Germany, Great Britain, and Turkey. They focus on the question how religious knowledge and ritual practice are constantly (re-)negotiated and (re-)distributed in Alevism and, as a comparison, in Yezidism. These processes are discussed in regard to the conditions of social and cultural change, transnational migration, and globalised communication. In doing so, the contributions to this volume follow different approaches and discuss fundamental methodological issues.

Das Zusammenleben von Menschen und Hunden ist von vielen Missverständnissen geprägt. Und wenn es hakt, suchen wir gern nach der "einen" Lösung. Der "einen" Lösung, die es jedoch nicht gibt. Denn unsere Hunde sind Persönlichkeiten, fühlende Wesen mit eigenem Charakter. Genau so möchten sie behandelt werden: respektvoll, wertschätzend und ihrem Wesen entsprechend. Wie das funktionieren kann, beschreiben wir in "Mensch Hund und". Hier geht es um Zusammenleben, Kommunikation und Gefühle. Es geht um Missverständnisse, populäre Irrtümer und Anleitung zur erfolgreichen Schulung. Um gute und weniger gute Entscheidungen. Es geht um Bindungsarbeit, Freude und Liebe. Aber es geht eben auch um Fehler, Gewalt, Krankheit und den Sterbeprozess. Und da sich in unserem Leben nicht alles nur um uns und unsere Hunde dreht, gibt es weitere Schauplätze, die wir in unserem Buch betreten. Themen, die uns wichtig sind. Dazu gehören Natur- und Tierrechte, Igelschutz, das Übernehmen von Verantwortung und beherztes Handeln. Was wir mit unserem Buch wollen? Wir möchten informieren, aufklären, unterstützen, inspirieren und motivieren. Damit alles in Bewegung bleibt, Schlechtes gut wird und Gutes noch viel besser. Wenn wir Menschen die Augen und das Herz öffnen können, haben wir viel erreicht.

16 erlebte Geschichten über Tiere von 13 Autoren. Zum Lesen und Vorlesen. Mal spannend, mal aufwühlend, mal lustig und immer kurzweilig. Unter anderem von den Autorinnen und Autoren Bärbel Ackerschott, Daniel Cazard, Sonja Dawid, Robert Langer, Silvia Orlando Akagi, Saskia Poschadel, Christine Reichmann, Melanie Schaumann, Angelika Schmelzer und Jörg Wolke.Der Erlös dieses Buches geht an die Initiative mensch-hund-und.de und kommt zu 100 % dem Tierschutz zugute.

Ziel dieses Bandes ist es, einen Einblick in die traditionellen Institutionen des Alevitentums zu geben und insbesondere deren Veranderungen im 20. Jahrhundert zu thematisieren. Der Sammelband soll einen Beitrag zur Erforschung der Geschichte, Praxis und aktuellen Lage der Organisation alevitischen religiosen Spezialistentums leisten.

The field of microfluidics has in the last decade permeated many disciplines, from physics to biology and chemistry, and from bioengineering to medical research. One of the most important applications of lab-on-a-chip devices in medicine and related disciplines is disease diagnostics, which involves steps from biological sample/analyte loading to storage, detection, and analysis. The chapters collected in this book detail recent advances in these processes using microfluidic devices and systems. The reviews of portable devices for diagnostic purposes are likely to evoke interest and raise new research questions in interdisciplinary fields (e.g., efficient MEMS/microfluidic engineering driven by biological and medical applications).The variety of the selected topics (general relevance of microfluidics in medical and bioengineering research, fabrication, advances in on-chip sample detection and analysis, and specific disease models) ensures that each of them can be viewed in the larger context of microfluidic-mediated diagnostics.

This book provides a glimpse into the life and work of Robert Langer, an amazing scientist, inventor and entrepreneur. Growing up in Albany, New York, Langer developed a passion for mathematics. While he was pretty good at science, he was very good at math. He went on to receive his BA in chemical engineering from Cornell University and his Doctorate of Science from the Massachusetts Institute of Technology. As a graduate student at MIT, he was involved in teaching underprivileged high school dropouts, his goal: to make math and science interesting.Langer's research laboratory at MIT is the largest biomedical engineering lab in the world. He has authored more than 1300 papers and holds more than 1080 patents. His patents have been licensed or sublicensed to more than 250 companies. A selection of 53 key papers and 50 patents are included in this book.Langer has pioneered many new technologies, including controlled release system and is regarded as the founder of tissue engineering in the field of regenerative medicine. However, his success did not come easily. He struggled in the late 1970s and early 1980s because scientists, especially established scientists, did not believe in his research. To obtain his first patent, Langer scoured existing literature and found a paper published by five famous chemists and chemical engineers that said his results were surprising and went against conventional thinking. He managed to get the patent after the five researchers confirmed that they really wrote the paper.The introductory chapter of the book gives an account of Langer's struggles as well as triumphs as he pursued research in biotechnology and tissue engineering in an effort to "make the world a better place and transform human healthcare." The book will appeal to both students and scientists.