Robert Stern – författare
701 kr
Skickas inom 10-15 vardagar
Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal.
The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book will offer a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer.
Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance1 834 kr
Skickas inom 5-8 vardagar
1 990 kr
Skickas inom 5-8 vardagar
1 477 kr
Skickas inom 5-8 vardagar
1 249 kr
Skickas inom 7-10 vardagar
1 200 kr
Skickas inom 5-8 vardagar
1 114 kr
Skickas inom 5-8 vardagar
1 251 kr
Skickas inom 5-8 vardagar
501 kr
Skickas inom 5-8 vardagar
1 049 kr
Skickas inom 7-10 vardagar
902 kr
Skickas inom 5-8 vardagar
1 526 kr
Skickas inom 5-8 vardagar
908 kr
Skickas inom 5-8 vardagar
805 kr
Skickas inom 5-8 vardagar
656 kr
Skickas inom 5-8 vardagar
734 kr
Skickas inom 10-15 vardagar
660 kr
Skickas inom 10-15 vardagar
629 kr
Skickas inom 10-15 vardagar
22 028 kr
Skickas inom 10-15 vardagar
2 151 kr
Skickas inom 10-15 vardagar
2 151 kr
Skickas inom 10-15 vardagar
380 kr
Skickas inom 10-15 vardagar
823 kr
Skickas inom 10-15 vardagar
2 206 kr
Skickas inom 10-15 vardagar
722 kr
Skickas inom 10-15 vardagar
1 240 kr
Skickas inom 7-10 vardagar
448 kr
Skickas inom 7-10 vardagar
2 201 kr
Skickas inom 10-15 vardagar
2 343 kr
Skickas inom 10-15 vardagar
306 kr
Skickas inom 5-8 vardagar