837 kr
Läs direkt efter köp
837 kr
Läs direkt efter köp
726 kr
Skickas inom 10-15 vardagar
Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal.
The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book will offer a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer.
Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance463 kr
Läs direkt efter köp
462 kr
Läs direkt efter köp
1 065 kr
Läs direkt efter köp
584 kr
Läs direkt efter köp
977 kr
Läs direkt efter köp
1 243 kr
Läs direkt efter köp
1 243 kr
Läs direkt efter köp
870 kr
Läs direkt efter köp
870 kr
Läs direkt efter köp
2 500 kr
Skickas inom 5-8 vardagar
2 677 kr
Skickas inom 5-8 vardagar
1 526 kr
Skickas inom 5-8 vardagar
1 686 kr
Skickas inom 3-6 vardagar
1 884 kr
Skickas inom 5-8 vardagar
1 546 kr
Skickas inom 3-6 vardagar
1 439 kr
Skickas inom 5-8 vardagar
518 kr
Skickas inom 5-8 vardagar
1 084 kr
Skickas inom 7-10 vardagar
932 kr
Skickas inom 5-8 vardagar
835 kr
Läs direkt efter köp
835 kr
Läs direkt efter köp
2 411 kr
Skickas inom 5-8 vardagar
1 172 kr
Skickas inom 5-8 vardagar
1 257 kr
Skickas inom 5-8 vardagar
946 kr
Skickas inom 5-8 vardagar
787 kr
Skickas inom 10-15 vardagar
599 kr
Skickas inom 5-8 vardagar
666 kr
Skickas inom 10-15 vardagar