Robert Stern - Böcker
711 kr
Skickas inom 7-10 vardagar
Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal.
The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book will offer a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer.
Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance1 844 kr
Skickas inom 5-8 vardagar
Transcendental Arguments and Scepticism
Answering the Question of Justification
2 019 kr
Skickas inom 5-8 vardagar
1 430 kr
Skickas inom 5-8 vardagar
1 200 kr
Skickas inom 7-10 vardagar
1 217 kr
Skickas inom 5-8 vardagar
1 130 kr
Skickas inom 5-8 vardagar
Kierkegaard's and Heidegger's Analysis of Existence and its Relation to Proclamation
1 269 kr
Skickas inom 5-8 vardagar
488 kr
Skickas inom 5-8 vardagar
1 010 kr
Skickas inom 7-10 vardagar
861 kr
Skickas inom 5-8 vardagar
1 548 kr
Skickas inom 5-8 vardagar
921 kr
Skickas inom 5-8 vardagar
Transcendental Arguments and Scepticism
Answering the Question of Justification
816 kr
Skickas inom 5-8 vardagar
659 kr
Skickas inom 5-8 vardagar
724 kr
Skickas inom 10-15 vardagar
652 kr
Skickas inom 10-15 vardagar
621 kr
Skickas inom 10-15 vardagar
20 913 kr
Skickas inom 10-15 vardagar
2 103 kr
Skickas inom 10-15 vardagar
2 103 kr
Skickas inom 10-15 vardagar
376 kr
Skickas inom 10-15 vardagar
812 kr
Skickas inom 10-15 vardagar
2 170 kr
Skickas inom 10-15 vardagar
717 kr
Skickas inom 10-15 vardagar
1 192 kr
Skickas inom 7-10 vardagar
428 kr
Skickas inom 7-10 vardagar
2 166 kr
Skickas inom 10-15 vardagar
2 306 kr
Skickas inom 10-15 vardagar
304 kr
Skickas inom 7-10 vardagar