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2 produkter
2 644 kr
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Polysaccharide Systems are of interest to a wide range of scientists and technologists, because of their special rheological properties. This book brings together research from all relevant disciplines to provide a link between rheological theory and industrial applications. The book begins with a comprehensive survey of the structure of polysaccharides, from molecular conformations in the solid state to supramolecular structures in solutions and gels. Chaper 2 reviews the main applications of polysaccharides in industry as specialty chemicals. The third chapter draws together the basic concepts of rheology and the different approaches to the modeling of rheological behaviors. Chapter 4 deals with the rheology of polysaccharide systems in detail and the final chapter is concerned with experimental measurements and instrumentation. Recommendations are made for the choice of suitable instruments and correct treatment of data. This is an essential reference source for chemical engineers, chemists and technologists, in the food, pharmaceutical, biomedical, textile, coatings and cosmetic industries. It will also be of value to academics researching in these areas.
Understanding Drug Release and Absorption Mechanisms
A Physical and Mathematical Approach
Inbunden, Engelska, 2006
2 053 kr
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Demand for better reliability from drug delivery systems has caused designers and researchers to move away from trial-and-error approaches and toward model-based methods of product development. Developing such models requires cross-disciplinary physical, mathematical, and physiological knowledge. Combining these areas under a single cover, Understanding Drug Release and Absorption Mechanisms builds a firm understanding ofall elements needed to conceive, build, and implement successful models of drug release.Written by experts with broad industrial and academic experience, this book discusses the underlying physical principles, shows how to build mathematical models based on these principles, and finally compares the resulting models with experimental results. The authors begin by introducing the basics of modeling, physiological details of gastrointestinal and dermal absorption pathways, rheology, mass transport and thermodynamics, dissolution and partitioning, as well as size effects on the dissolution of crystallites. From this baseline, the authors explore applications in drug release from various delivery systems, specifically matrix systems, microemulsions, and permeability through membranes. Working systematically from theory to working models, Understanding Drug Release and Absorption Mechanisms: A Physical and Mathematical Approach demonstrates the steps involved in designing, building, and implementing realistic and reliable models of drug release without unrealistically simplifying the theoretical parameters.