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Multi-scale and Multi-physics Simulation of Fracture and Fatigue presents a comprehensive exploration of theoretical and computational methods used in the analysis of fracture and fatigue in materials, effectively bridging length and time scales. It explores both fundamental concepts of fracture mechanics and cutting-edge multi-scale computational modeling.By focusing on methods to predict material properties, including fracture toughness, based on nanoscale interactions up to macro-scale failure, the book employs physics-based techniques derived from quantum mechanics, molecular dynamics, and mechanics of materials. These approaches enable readers to uncover structure-property relationships within materials and predict material stiffness properties, aligning with the foundational principles of Integrated Computational Materials Engineering (ICME).Through its detailed discussion of multi-scale and multi-physics techniques essential for fatigue and fracture analysis, the book serves as a thorough guide for analyzing fatigue and fracture in both conventional polymers and innovative materials, including nano-structures.This book is an invaluable resource for material scientists and mechanical engineers with an interest in multiscale modeling of fracture and fatigue. Additionally, online figure slides are available to complement the content, providing further support for readers.