Stefan Offermanns – författare
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43 produkter
43 produkter
14 486 kr
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This fully updated third edition of the encyclopedia covers all aspects of pharmacology, from the chemistry of drugs and the biochemistry of drug targets to the clinical application of drugs, with emphasis on molecular mechanisms. It also includes techniques for describing the effects of drugs and characterizing drug targets. With over 2,000 entries and 350 detailed essays by leading experts, this book is also an up-to-date and important reference for scientists in fields outside pharmacology, students, health care workers, teachers, physicians, and laypersons. Available both in print and as a fully searchable and hyperlinked electronic online edition.
E-bok
Engelska, 202214 935 kr
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This fully updated third edition of the encyclopedia covers all aspects of pharmacology, from the chemistry of drugs and the biochemistry of drug targets to the clinical application of drugs, with emphasis on molecular mechanisms. It also includes techniques for describing the effects of drugs and characterizing drug targets. With over 2,000 entries and 350 detailed essays by leading experts, this book is also an up-to-date and important reference for scientists in fields outside pharmacology, students, health care workers, teachers, physicians, and laypersons.
Available both in print and as a fully searchable and hyperlinked electronic online edition.
Inbunden, Engelska
22 476 kr
Kommande
Del 164 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology, Vol. 164
Inbunden, Engelska, 2013
1 123 kr
Skickas inom 10-15 vardagar
T. Hara, I. Kimura, D. Inoue, A. Ichimura, and A. Hirasawa: Free fatty acid receptors and their role in regulation of energy metabolism. B. Nilius and G. Appendino. Spices: the savory and healthy science of pungency.
E-bok
PDF, Engelska, 20141 408 kr
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T. Hara, I. Kimura, D. Inoue, A. Ichimura, and A. Hirasawa: Free fatty acid receptors and their role in regulation of energy metabolism. B. Nilius and G. Appendino. Spices: the savory and healthy science of pungency.
Del 165 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology, Vol. 165
Inbunden, Engelska, 2013
1 123 kr
Skickas inom 10-15 vardagar
T. Büch, E. Schäfer, D. Steinritz, A. Dietrich, T. Gudermann: Chemosensory TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential as "Sweet Spots" for Targeted Therapies. D.C. Zebrowski and F. B. Engel: The Cardiomyocyte Cell Cycle in Hypertrophy, Tissue Homeostasis, and Regeneration. P. Hegyi and O.H. Petersen: The Exocrine Pancreas: The Acinar -Ductal Tango in Physiology and Pathophysiology.
E-bok
PDF, Engelska, 20131 459 kr
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T. Büch, E. Schäfer, D. Steinritz, A. Dietrich, T. Gudermann: Chemosensory TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential as "Sweet Spots" for Targeted Therapies. D.C. Zebrowski and F. B. Engel: The Cardiomyocyte Cell Cycle in Hypertrophy, Tissue Homeostasis, and Regeneration. P. Hegyi and O.H. Petersen: The Exocrine Pancreas: The Acinar -Ductal Tango in Physiology and Pathophysiology.
Del 166 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology 166
Inbunden, Engelska, 2014
1 123 kr
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The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
E-bok
PDF, Engelska, 20141 420 kr
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The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Del 167 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology, Vol. 167
Inbunden, Engelska, 2014
1 123 kr
Skickas inom 10-15 vardagar
The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
E-bok
PDF, Engelska, 20141 408 kr
Läs direkt efter köp
The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Häftad, Engelska, 2016
1 123 kr
Skickas inom 10-15 vardagar
T. Büch, E. Schäfer, D. Steinritz, A. Dietrich, T. Gudermann: Chemosensory TRP Channels in the Respiratory Tract: Role in Toxic Lung Injury and Potential as "Sweet Spots" for Targeted Therapies. D.C. Zebrowski and F. B. Engel: The Cardiomyocyte Cell Cycle in Hypertrophy, Tissue Homeostasis, and Regeneration. P. Hegyi and O.H. Petersen: The Exocrine Pancreas: The Acinar -Ductal Tango in Physiology and Pathophysiology.
Häftad, Engelska, 2016
1 482 kr
Skickas inom 5-8 vardagar
T. Hara, I. Kimura, D. Inoue, A. Ichimura, and A. Hirasawa: Free fatty acid receptors and their role in regulation of energy metabolism. B. Nilius and G. Appendino. Spices: the savory and healthy science of pungency.
Häftad, Engelska, 2016
1 443 kr
Skickas inom 5-8 vardagar
The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Häftad, Engelska, 2016
1 123 kr
Skickas inom 10-15 vardagar
The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
Inbunden, Engelska, 2004
1 123 kr
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H. Wegele, L. Müller, and J. Buchner: Hsp70 and Hsp90 – A Relay Team for Protein Folding R. Schülein: The Early Stages of the Intracellular Transport of Membrane Proteins: Clinical and Pharmacological Implications L. Schild: The Epithelial Sodium Channel: From Molecule to Disease
Inbunden, Engelska, 2005
1 125 kr
Skickas inom 10-15 vardagar
The eukaryotic translation machinery must recognize the site on a messenger RNA (mRNA) where decoding should begin and where it should end. The selection of the translation start site is generally given by the ?rst AUG codon encoding the amino acid methionine. D- ing initiation soluble translation initiation factors (eukaryotic translation initiation factors [eIFs] in eukaryotes and prokaryotic translation initiation factors [IFs] in prokaryotes) bind the mRNA, deliver the initiator Met-tRNA, and assemble to form a complete 80S ribosome from the 40S and 60S subunits. By progressing along the mRNA in the 5 -to-3 direction the ribosome decodes the information and translates it into the polypeptide chain. During this process, repeated delivery of amino-acyl tRNA (aa-tRNA) to the ribosome, peptide bond formation, movement of the mRNA, and the growing peptidyl-tRNA is mediated by both soluble elongation factors (eukaryotic translation elongation factors [eEFs] in euka- otes and prokaryotic translation elongation factors [EFs] in prokaryotes) and the activity of the ribosome. The ?nal step in the translation process occurs when one of the three t- mination codons occupies the ribosomal A-site.Translation comes to an end and soluble release factors (eukaryotic translation termination factors [eRFs] in eukaryotes and proka- otic translation termination factors [RFs] in prokaryotes) facilitate hydrolytical release of the polypeptide chain (for recent reviews, see Inge-Vechtomov et al. 2003; Kisselev et al. 2003; Wilson and Nierhaus 2003; Kapp and Lorsch 2004).
E-bok
PDF, Engelska, 20061 408 kr
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E-bok
PDF, Engelska, 20062 972 kr
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This comprehensive encyclopedic reference provides rapid access to focused information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of about 2000 entries, about 200 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology describing drug action as well as the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms and general principles. Each essay is well-structured, with extensive cross-referencing between all entries. The book is accompanied by a CD-ROM which provides the full text and facilitated searches.
Del 156 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology 156
Inbunden, Engelska, 2006
1 125 kr
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Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH~1) as a result + – of H and Cl ion secretion [hydrochloric acid (HCl) production] by parietal cells in the oxyntic mucosa of the stomach. The combined output of the parietal cells leads to the sec- tion of 1–2 l of HCl at a concentration of 150–160 mmol/l into the interior of the stomach. In order to facilitate the production of acid, the parietal cell relies on the generation of a high + concentration of H ions that are transported into the lumen of the gland. This process is fa- + + cilitated by activation of the gastric H ,K -ATPase, which translocates to the apical pole of + – the parietal cell. K as well as ATP hydrolysis and Cl all play critical roles in the activation + + of gastric H ,K -ATPase and are essential for the functioning of the enzyme (Reenstra and Forte 1990). This review will examine the classical proteins that have been linked to acid secretion as well as some recently identi?ed proteins that may modulate gastric acid secretion, in - dition we discuss the known secretagogues, and their receptors including a new receptor, which upon stimulation can lead to acid secretion.
E-bok
PDF, Engelska, 20071 408 kr
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Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH~1) as a result + – of H and Cl ion secretion [hydrochloric acid (HCl) production] by parietal cells in the oxyntic mucosa of the stomach. The combined output of the parietal cells leads to the sec- tion of 1–2 l of HCl at a concentration of 150–160 mmol/l into the interior of the stomach. In order to facilitate the production of acid, the parietal cell relies on the generation of a high + concentration of H ions that are transported into the lumen of the gland. This process is fa- + + cilitated by activation of the gastric H ,K -ATPase, which translocates to the apical pole of + – the parietal cell. K as well as ATP hydrolysis and Cl all play critical roles in the activation + + of gastric H ,K -ATPase and are essential for the functioning of the enzyme (Reenstra and Forte 1990). This review will examine the classical proteins that have been linked to acid secretion as well as some recently identi?ed proteins that may modulate gastric acid secretion, in - dition we discuss the known secretagogues, and their receptors including a new receptor, which upon stimulation can lead to acid secretion.
E-bok
PDF, Engelska, 200848 kr
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An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
E-bok
PDF, Engelska, 20071 408 kr
Läs direkt efter köp
H. Wegele, L. Müller, and J. Buchner: Hsp70 and Hsp90 – A Relay Team for Protein Folding R. Schülein: The Early Stages of the Intracellular Transport of Membrane Proteins: Clinical and Pharmacological Implications L. Schild: The Epithelial Sodium Channel: From Molecule to Disease
Del 160 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology 160
Inbunden, Engelska, 2008
1 125 kr
Skickas inom 10-15 vardagar
E-bok
PDF, Engelska, 20081 408 kr
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Del 161 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology 161
Inbunden, Engelska, 2011
1 684 kr
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F. Schweda and A. Kurtz: Regulation of Renin Release by Local and Systemic FactorsM. Krauss and V. Haucke: Shaping Membranes for EndocytosisB.M. Jockusch and P.L. Graumann: The Long Journey: Actin on the Road to Pro- and Eukaryotic CellsB. Colsoul, R. Vennekens and B. Nilius: Transient Receptor Potential (TRP) Cation Channels in Pancreatic ß cells
E-bok
PDF, Engelska, 20112 036 kr
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F. Schweda and A. Kurtz: Regulation of Renin Release by Local and Systemic FactorsM. Krauss and V. Haucke: Shaping Membranes for EndocytosisB.M. Jockusch and P.L. Graumann: The Long Journey: Actin on the Road to Pro- and Eukaryotic CellsB. Colsoul, R. Vennekens and B. Nilius: Transient Receptor Potential (TRP) Cation Channels in Pancreatic ß cells
Del 151 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology 151
Häftad, Engelska, 2010
1 125 kr
Skickas inom 10-15 vardagar
H. Wegele, L. Müller, and J. Buchner: Hsp70 and Hsp90 – A Relay Team for Protein Folding R. Schülein: The Early Stages of the Intracellular Transport of Membrane Proteins: Clinical and Pharmacological Implications L. Schild: The Epithelial Sodium Channel: From Molecule to Disease
Del 155 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology 155
Häftad, Engelska, 2010
1 125 kr
Skickas inom 10-15 vardagar
The eukaryotic translation machinery must recognize the site on a messenger RNA (mRNA) where decoding should begin and where it should end. The selection of the translation start site is generally given by the ?rst AUG codon encoding the amino acid methionine. D- ing initiation soluble translation initiation factors (eukaryotic translation initiation factors [eIFs] in eukaryotes and prokaryotic translation initiation factors [IFs] in prokaryotes) bind the mRNA, deliver the initiator Met-tRNA, and assemble to form a complete 80S ribosome from the 40S and 60S subunits. By progressing along the mRNA in the 5 -to-3 direction the ribosome decodes the information and translates it into the polypeptide chain. During this process, repeated delivery of amino-acyl tRNA (aa-tRNA) to the ribosome, peptide bond formation, movement of the mRNA, and the growing peptidyl-tRNA is mediated by both soluble elongation factors (eukaryotic translation elongation factors [eEFs] in euka- otes and prokaryotic translation elongation factors [EFs] in prokaryotes) and the activity of the ribosome. The ?nal step in the translation process occurs when one of the three t- mination codons occupies the ribosomal A-site.Translation comes to an end and soluble release factors (eukaryotic translation termination factors [eRFs] in eukaryotes and proka- otic translation termination factors [RFs] in prokaryotes) facilitate hydrolytical release of the polypeptide chain (for recent reviews, see Inge-Vechtomov et al. 2003; Kisselev et al. 2003; Wilson and Nierhaus 2003; Kapp and Lorsch 2004).
Del 156 - Reviews of Physiology, Biochemistry and Pharmacology
Reviews of Physiology, Biochemistry and Pharmacology 156
Häftad, Engelska, 2010
1 125 kr
Skickas inom 10-15 vardagar
Gastric acid plays a primary role in digestion as well as in the sterilization of food and water. Gastric juice contains the most concentrated physiological acid solution (pH~1) as a result + – of H and Cl ion secretion [hydrochloric acid (HCl) production] by parietal cells in the oxyntic mucosa of the stomach. The combined output of the parietal cells leads to the sec- tion of 1–2 l of HCl at a concentration of 150–160 mmol/l into the interior of the stomach. In order to facilitate the production of acid, the parietal cell relies on the generation of a high + concentration of H ions that are transported into the lumen of the gland. This process is fa- + + cilitated by activation of the gastric H ,K -ATPase, which translocates to the apical pole of + – the parietal cell. K as well as ATP hydrolysis and Cl all play critical roles in the activation + + of gastric H ,K -ATPase and are essential for the functioning of the enzyme (Reenstra and Forte 1990). This review will examine the classical proteins that have been linked to acid secretion as well as some recently identi?ed proteins that may modulate gastric acid secretion, in - dition we discuss the known secretagogues, and their receptors including a new receptor, which upon stimulation can lead to acid secretion.