Subhash C. Mandal – författare

Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery.

Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers.

Reviews the changing role of natural products in drug discovery, integrating traditional knowledge with modern molecular technologies Highlights the potential future role of natural products in preventative medicine Supported by real world case studies throughout

Essentials of Botanical Extraction: Principles and Applications provides a unique, single source of valuable information on the various botanical extraction methods available, from conventional to the use of green and modern extraction technologies including ultrasounds, microwaves, pressurized liquids, and supercritical fluids. Most extracts obtained from botanicals are often poorly characterized with unidentified active or inactive constituents. A wise selection of an extraction strategy is vital to drug discovery from medicinal plants as extraction forms the basic first step in medicinal plant research. This book also explores the mathematical hypotheses and innovations in botanical extractions and analyzes different post extraction operations so that dependency on serendipity is reduced and the same be converted into programmed drug discovery.

Reviews the history and current state of natural product drug discovery and development, highlighting successes and current issues Explains the application of chemometric tools in extraction process design and method development Introduces process intensification as applied to the processing of medicinal plant extracts for rapid and cost-effective extraction

Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry. This book examines important herbal biomolecules including alkaloids, glycosides, flavonoids, anthraquinones, steroids, polysaccharides, tannins and polyphenolic compounds, terpenes, fats and waxes, proteins and peptides, and vitamins. These herbal biomacromolecules are responsible for different bioactivities as well as pharmacological potentials. A systematic understanding of the extraction, purification, characterization, applications of these herbal biomolecules and their derivatives in healthcare fields is developed in this comprehensive book. Chapters explore the key topics along with an emphasis on recent research and developments in healthcare fields by leading experts. They include updated literature review of the relevant key topics, good quality illustrations, chemical structures, flow charts, well-organized tables and case studies. Herbal Biomolecules in Healthcare Applications will be useful for researchers working on natural products and biomolecules with bioactivity and nutraceutical properties. Professionals specializing in scientific areas such as biochemistry, pharmacology, analytical chemistry, organic chemistry, clinics, or engineering focused on bioactive natural products will find this book useful.

Provides a study of different type of biomolecules from herbal extracts and their bioactivities as well as their application in the healthcare industry Contributions by global leaders and experts from academia, industry and regulatory agencies, who have been considered as pioneers in the application of herbal biomolecules in the diverse healthcare fields Includes updated literature review along with practical examples and research case studies

Nanobiomaterials and Nanomedicines for Metabolic Disorders delves into the transformative role of nanotechnology in addressing metabolic disorders. The book begins with an overview of nanoparticle classifications and then explores the synthesis of biomaterials and drug delivery systems. In addition, it explores innovative diagnostic and imaging techniques while presenting cutting-edge therapeutic approaches. Later chapters focus on specific metabolic disorders, such as cardiovascular and lifestyle-related conditions. The book is tailored to researchers, students, and healthcare professionals seeking advanced theranostic approaches to these disorders. By bridging nanotechnology with metabolic pathways, the text offers insights into how targeted nanomedicines can improve therapeutic outcomes.Utilizes an interdisciplinary approach, bridging the fields of materials science and biomedical science to improve translational efficiencyCovers a range of nanoparticles and nanotechnologies for the diagnosis and treatment of metabolic disorders, aiding readers to select the most suitable for their workDetails various metabolic pathways and disorders, including glycogen and lysosomal storage, type 2 diabetes, obesity, and metabolic vascular disorders

The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc.

The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc.

This book addresses all aspects of diet in preventing and managing Alzheimer's disease. It highlights the role of specific dietary components like polyphenols, flavonoids, catechins, lignans etc., along with various dietary patterns in improving neuronal health and mitigating the symptoms of disease.Role of diet and its impact on overall health and well-being have emerged as promising areas of research. The comprehensive and holistic approach offered in the book provides a thorough scientific view of dietary components in preventing, managing or delaying the onset of Alzheimer’s disease (AD). By incorporating the most recent scientific research and evidence-based practices, this book presents the necessary knowledge and tools to improve cognitive health and enhance quality of life through dietary choices. In addition, this book also gives an overview of the latest scientific contributions in the field of the pathophysiology of this disease and how this understanding helps in developing newer therapeutic interventions.With high-quality images, chemical structures, and well-structured tables, the book aims to present intricate information in an accessible and interesting manner. By incorporating research case studies, the book not only educates but also motivates readers to take tangible steps towards effective dietary management.Thus this book serves as a crucial guide for utilizing the potential of nutrition in the battle against Alzheimer's disease. It is mainly targeted at nutritionists, post graduate students, researchers and biochemists working in the area of Alzheimer's.

This book provides a thorough insight into the comprehensive and up-to-date trends of phytomedicines in the management of lifestyle diseases and its mechanisms, modern methods of extraction and purification of phytoconstituents, and chemical characterization as well as standardization of phytoconstituents using modern equipments.