Vivekananda Mandal – författare

Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery.

Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers.

Reviews the changing role of natural products in drug discovery, integrating traditional knowledge with modern molecular technologies Highlights the potential future role of natural products in preventative medicine Supported by real world case studies throughout

Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery.Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers.- Reviews the changing role of natural products in drug discovery, integrating traditional knowledge with modern molecular technologies- Highlights the potential future role of natural products in preventative medicine- Supported by real world case studies throughout

Essentials of Botanical Extraction: Principles and Applications provides a unique, single source of valuable information on the various botanical extraction methods available, from conventional to the use of green and modern extraction technologies including ultrasounds, microwaves, pressurized liquids, and supercritical fluids. Most extracts obtained from botanicals are often poorly characterized with unidentified active or inactive constituents. A wise selection of an extraction strategy is vital to drug discovery from medicinal plants as extraction forms the basic first step in medicinal plant research. This book also explores the mathematical hypotheses and innovations in botanical extractions and analyzes different post extraction operations so that dependency on serendipity is reduced and the same be converted into programmed drug discovery.

Reviews the history and current state of natural product drug discovery and development, highlighting successes and current issues Explains the application of chemometric tools in extraction process design and method development Introduces process intensification as applied to the processing of medicinal plant extracts for rapid and cost-effective extraction

Essentials of Botanical Extraction: Principles and Applications provides a unique, single source of valuable information on the various botanical extraction methods available, from conventional to the use of green and modern extraction technologies including ultrasounds, microwaves, pressurized liquids, and supercritical fluids. Most extracts obtained from botanicals are often poorly characterized with unidentified active or inactive constituents. A wise selection of an extraction strategy is vital to drug discovery from medicinal plants as extraction forms the basic first step in medicinal plant research. This book also explores the mathematical hypotheses and innovations in botanical extractions and analyzes different post extraction operations so that dependency on serendipity is reduced and the same be converted into programmed drug discovery.- Reviews the history and current state of natural product drug discovery and development, highlighting successes and current issues- Explains the application of chemometric tools in extraction process design and method development- Introduces process intensification as applied to the processing of medicinal plant extracts for rapid and cost-effective extraction

This book presents the impact of a wide array of xenobiotic compounds on the physio-biochemical and molecular parameters in an integrative format. It highlights recent advances in bioremediation strategies, including the use of novel microorganisms, rhizosphere engineering, microbial enzymes, and nanotechnology. By exploring the effects of xenobiotic exposure on plants and microbes holistically, this book aims to boost sustainable agriculture for the future.Key concepts include the mechanisms and strategies plants employ for detoxifying xenobiotics, microbial mitigation of plant stress, and the role of nanobiosensors in environmental monitoring. Chapters delve into topics such as the ecological impacts of emerging pollutants, plant-microbe interactions under environmental stress, and innovative bioremediation techniques. This comprehensive analysis makes the book a must-read for understanding the challenges and solutions in managing xenobiotic impacts. Researchers, scholars, and scientists in Plant Sciences, Agriculture, and related fields will find this book invaluable. With illustrative schemes and sketches, the book effectively communicates complex ideas, drawing attention to the critical challenges of future food production and environmental issues. It is particularly relevant for academics, practitioners, and policymakers seeking to understand and address the impacts of xenobiotics on ecosystems. By providing a detailed exploration of current research and innovative solutions, the book serves as a vital resource for those committed to fostering a sustainable future.

This book presents the impact of a wide array of xenobiotic compounds on the physio-biochemical and molecular parameters in an integrative format. It highlights recent advances in bioremediation strategies, including the use of novel microorganisms, rhizosphere engineering, microbial enzymes, and nanotechnology. By exploring the effects of xenobiotic exposure on plants and microbes holistically, this book aims to boost sustainable agriculture for the future.Key concepts include the mechanisms and strategies plants employ for detoxifying xenobiotics, microbial mitigation of plant stress, and the role of nanobiosensors in environmental monitoring. Chapters delve into topics such as the ecological impacts of emerging pollutants, plant-microbe interactions under environmental stress, and innovative bioremediation techniques. This comprehensive analysis makes the book a must-read for understanding the challenges and solutions in managing xenobiotic impacts. Researchers, scholars, and scientists in Plant Sciences, Agriculture, and related fields will find this book invaluable. With illustrative schemes and sketches, the book effectively communicates complex ideas, drawing attention to the critical challenges of future food production and environmental issues. It is particularly relevant for academics, practitioners, and policymakers seeking to understand and address the impacts of xenobiotics on ecosystems. By providing a detailed exploration of current research and innovative solutions, the book serves as a vital resource for those committed to fostering a sustainable future.