Talbot - Böcker

The identification and characterisation of genes from filamentous fungi has become easier because of the rapid advances that have taken place in molecular biology, including the generation of whole genome sequences. The new challenge facing researchers is to determine the functions of genes and how they contribute to the biology of fungi. To do this, it is clear that a wide variety of different experimental techniques will be necessary, ranging from classical genetic analysis and mutant production, right through to cell biology, biochemistry and immunological methods. This book brings together detailed practical guidance from experienced researchers using the full range of these genetic, genomic, cellular and biochemical methods. The authors describe laboratory procedures that have been proven effective for the investigation of a wide variety of fungal species. They give key background information, technical tips and detailed experimental protocols, which will prove invaluable to researchers and students studying filamentous fungi.

The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not only is it necessary to detect new adverse drug reactions, but the principles and practice of pharmacovigilance apply to the surveillance of a wide range of medicinal products. Stephens' Detection and Evaluation of Adverse Drug Reactions provides a comprehensive review of all aspects of adverse drug reactions throughout the life cycle of a medicine, from toxicology and clinical trials through to pharmacovigilance, risk management, and legal and regulatory requirements. It also covers the safety of biotherapeutics and vaccines and includes new chapters on pharmacogenetics, proactive risk management, societal considerations, and the safety of drugs used in oncology and herbal medicines.This sixth edition of the classic text on drug safety is an authoritative reference text for all those who work in pharmacovigilance or have an interest in adverse drug reactions, whether in regulatory authorities, pharmaceutical companies, or academia.Praise for previous editions"This book presents a comprehensive and wide-ranging overview of the science of pharmacovigilance. For those entering or already experienced in the pharmaceutical sciences, this is an essential work.” - from a review in E-STREAMS"...a key text in the area of pharmacovigilance...extensively referenced and well-written...a valuable resource..." - from a review in The Pharmaceutical Journal