Toshio Nakanishi – författare

This volume focuses on the etiology and morphogenesis of congenitalheart diseases. It reviews in detail the early development and differentiation ofthe heart, and later morphologic events of the cardiovascular system, coveringa wide range of topics such as gene functions, growth factors, transcriptionfactors and cellular interactions that are implicated in cardiac morphogenesisand congenital heart disease. This book also presents recent advances in stemcell and cell sheet tissue engineering technologies which have the potential toprovide novel in vitro disease models and to generate regenerative paradigmsfor cardiac repair and regeneration.   Thisis the ideal resource for physician scientists and investigators looking forupdates on recent investigations on the origins of congenital heart disease andpotential future therapies.

This volume focuses on the etiology and morphogenesis of congenitalheart diseases. It reviews in detail the early development and differentiation ofthe heart, and later morphologic events of the cardiovascular system, coveringa wide range of topics such as gene functions, growth factors, transcriptionfactors and cellular interactions that are implicated in cardiac morphogenesisand congenital heart disease. This book also presents recent advances in stemcell and cell sheet tissue engineering technologies which have the potential toprovide novel in vitro disease models and to generate regenerative paradigmsfor cardiac repair and regeneration.   Thisis the ideal resource for physician scientists and investigators looking forupdates on recent investigations on the origins of congenital heart disease andpotential future therapies.

This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.