Van G. Wilson – författare

This book guides through the fascinating world of viruses and makes readers enjoy science in an accessible way.

This book guides through the fascinating history of viral vaccines, from the first primitive smallpox vaccination in the 18th century to the cutting-edge RSV formulation approved in 2023. Each chapter delves into the scientific, clinical, and social forces that led to the development of these life-saving medical innovations, highlighting the scientists who played pivotal roles. With a focus on making complex science accessible and history engaging, this book offers a comprehensive portrayal of virology, vaccinology and the interplay between science and society in shaping public health.Readers will explore key concepts such as the evolution of vaccine technology over time, from cowpox material to mRNA vaccines, and a wide array of other topics, including the eradication of diseases through vaccines, the challenges of immunization against influenza, and the revolutionary impact of COVID-19 vaccination. The author, microbiologist Professor Wilson, provides expert analysis on how sociological factors influenced vaccine progress and gets to the bottom of the question of why there is still no vaccine for some critical diseases.This book is a must-read for anyone with an interest in viruses and vaccines. Whether you're a researcher or simply fascinated by medical history, this book promises to be both informative and entertaining.

This is the second edition of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule. Individual chapters explore the biochemistry, molecular biology, and cell biology of the sumoylation system and its substrate proteins.The book is divided into three themed parts: Molecular Functions (I), Cell Growth Regulation (II), and Diseases (III). Parts I and II focus on the contribution of sumoylation to cellular activities in both the nuclear and cytoplasmic compartments. The nuclear activities covered include nucleic acid metabolism (both RNA and DNA), chromosome structure and replication, and nucleocytoplasmic transport. Cytoplasmic processes presented include regulation of membrane ion channels, general metabolism, and apoptotic signalling. Topics in Part III include the role of sumoylation in developmental abnormalities (craniofacial and cardiovascular), diabetes, neurodegenerative diseases, cancer, and infections with viruses and bacteria.Each of the corresponding chapter authors is an active researcher who has made significant contributions to understanding sumoylation. This second edition provides updates and revisions to most of the original chapters plus adds six new chapters to address important developing areas of sumoylation research.This volume is intended for a scientific audience from undergraduates to independent researchers. The content will serve as both a solid introduction for the novice reader and an in depth treatment for the advanced scholar.