SUMO Regulation of Cellular Processes

Häftad, Engelska, 2018

Del i serien Advances in Experimental Medicine and Biology

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Beskrivning

Topics in Part III include the role of sumoylation in developmental abnormalities (craniofacial and cardiovascular), diabetes, neurodegenerative diseases, cancer, and infections with viruses and bacteria.Each of the corresponding chapter authors is an active researcher who has made significant contributions to understanding sumoylation.

Produktinformation

Utgivningsdatum:2018-06-20
Mått:178 x 254 x 23 mm
Vikt:793 g
Format:Häftad
Språk:Engelska
Serie:Advances in Experimental Medicine and Biology
Antal sidor:415
Upplaga:2
Förlag:Springer International Publishing AG
ISBN:9783319843049

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Innehållsförteckning

Preface.- Introduction to Sumoylation.- Part I Molecular Functions.- Roles of Sumoylation in mRNA Processing and Metabolsim.- SUMO and Chromatin Remodeling.- Functions of SUMO in the Maintenance of Genome Stability.- Regulation of Cellular Processes by SUMO: Understudied Topics.- The Molecular Interface Between The SUMO And Ubiquitin Systems.- . SUMO and Nucleocytoplasmic Transport.- SUMO Modification of Ion Channels.- The Roles of SUMO in Metabolic Regulation .- Part II Cell Growth Regulation.- The SUMO Pathway in Mitosis.- Wrestling with Chromosomes: The Roles of SUMO During Meiosis.- Sumoylation in Development and Differentiation.- The Role of Sumoylation in Senescence.- Regulation of Plant Cellular and Organismal Development by SUMO.- SUMO in Drosophila Development.- Part III Diseases.- SUMOylation: Implications for Neurodegenerative Diseases.- Sumoylation and Its Contribution to Cancer.- Sumoylation Modulates the Susceptibility to Type 1 Diabetes.- Sumoylation in Craniofacial Disorders.- Coordination of Cellular Localization-Dependent Effects of Sumoylation in Regulating Cardiovascular and Neurological Diseases.- Viral Interplay with the Host Sumoylation System.- SUMOylation as an Integral Mechanism in Bacterial Infection and Disease Pathogenesis.- Index.