Vittorio Pace – författare

Provides a unique summary of homologation strategies in organic synthesis Homologation Reactions presents different concepts underpinning the use of homologating reagents as well as their applications in organic synthesis. It covers in-depth discussions on the rationales governing this kind of transformations with a strong emphasis on mechanistic elements modulating critical aspects (e.g. selectivity) of the processes. In addition, this two-volume work features: Metal carbenoids, ylides, and diazo reagentsHomologating agents working under nucleophilic, electrophilic, and radical regimeHomologations realized on boron-containing or carbon-centered linchpinsUse of highly sensitive fluorinated homologating agentsProgressive homologations and the concept of assembly line synthesisHomologation processes followed by rearrangement cascadesConstruction of cyclic motifs and ring-expansionHomologation reactions with carbon monoxide and carbon dioxideNew and/or challenging directions to expect in the futureWritten by an international team of leaders in the field, the book is a useful guide for designing effective transformations by using homologation reactions. It is a must-read for every synthetic chemist in academia and industry!