On February 21 and 22, 1975, an International Workshop on the "Genetics of Diabetes Mellitus" was held in Göttingen, West-Germany. This workshop had been organized hy the Department of Medicine, University of Göttingen, and was generously sponsored by the Deutsche Forschungsgemeinschaft. Some forty geneticists and clinicians from Europe and N orth America, working in the field of diabetes both in man and laboratory animals, participated. The 25lectures presented at the workshop are now assembled for publication. Some of the animated discussion which followed the presentations has been included in the final papers by the speakers. Some lectures summarize the recent literature, others present data from recent research. Thus, a comprehensive and modem review of the theoretical and practical problems of diabetes are offered by this volume. related to the genetics The confusion about the mode of inheritance of diabetes mellitus during the last two decades can only be resolved by joint discussions between geneticists interested in diabetes and clinical diabetologists interested in genetics. Knowledge of modem genetics and of the heterogeneity of diabetes mellitus are necessary in order to disentangle the complex scene. Optimistically, the publication of this work on the genetics of diabetes will help to achieve this aim and to establish the concept of genetic heterogeneity of diabetes mellitus. The editors are grateful to Springer-Verlag, Heidelberg, for the prompt publication of these proceedings and to the Farbwerke Hoechst AG, Frankfurt (M), for their contribution to the printing costs.

New principles for the treatment of diabetes are described in this volume. Experts present experimental and clinical data on treatment with acarbose, an alpha-glucosidase inhibitor that delays absorption of fast carbohydrates. Toxicologic, pharmacologic and metabolic effects of acarbose are discussed. A concluding section on the future aspects of alpha-glucosidase inhibition offers a fair assessment of therapeutic possibilities.

Seit der 1. Auflage gab es so wesentliche Neuerungen, vor allem in der Therapie, daß es notwendig war, das Werk fast völlig neu zu konzipieren und zu schreiben. Wie außerordentlich das Wissen in der Gastroenterologie in den letzten Jahren angewachsen ist, zeigt quantitativ der Umfang des Buches. Eigentlich gibt es jetzt keine 2. Auflage, sondern eine annähernd komplette Neukonzeption. Der Begriff "Chirurgische Gastroenterologie" beinhaltet sowohl die gastroenterologische Chirurgie als auch das notwendige Wissen, um eine adäquate Diagnostik und Entscheidungsfindung bei gastroenterologischen Erkrankungen herbeizuführen. Das Buch vermittelt nicht nur das moderne Wissen zur Pathophysiologie und Pathogenese gastroenterologischer Erkrankungen, sondern auch die zielstrebige Diagnostik und Indikationsstellung zur gastroenterologischen Chirurgie. Der interessierte Leser kann alle notwendigen Informationen finden, die zum Verständnis gastroenterologischer Erkrankungen und chirurgischer Entscheidungen notwendig sind - beschrieben von den jeweiligen Kapazitäten. Damit ist das Buch nicht nur für Chirurgen wertvoll, sondern auch für Gastroenterologen und Internisten, die sich über die chirurgischen Möglichkeiten bei Erkrankungen des Verdauungstrakts informieren möchten. Auch Vertreter anderer an der Behandlung gastroenterologischer Erkrankungen beteiligten Disziplinen wie Röntgenologie, Strahlentherapie, Nuklearmedizin, Onkologie etc. finden wesentliche Informationen.

On February 21 and 22, 1975, an International Workshop on the "Genetics of Diabetes Mellitus" was held in Göttingen, West-Germany. This workshop had been organized hy the Department of Medicine, University of Göttingen, and was generously sponsored by the Deutsche Forschungsgemeinschaft. Some forty geneticists and clinicians from Europe and N orth America, working in the field of diabetes both in man and laboratory animals, participated. The 25lectures presented at the workshop are now assembled for publication. Some of the animated discussion which followed the presentations has been included in the final papers by the speakers. Some lectures summarize the recent literature, others present data from recent research. Thus, a comprehensive and modem review of the theoretical and practical problems of diabetes are offered by this volume. related to the genetics The confusion about the mode of inheritance of diabetes mellitus during the last two decades can only be resolved by joint discussions between geneticists interested in diabetes and clinical diabetologists interested in genetics. Knowledge of modem genetics and of the heterogeneity of diabetes mellitus are necessary in order to disentangle the complex scene. Optimistically, the publication of this work on the genetics of diabetes will help to achieve this aim and to establish the concept of genetic heterogeneity of diabetes mellitus. The editors are grateful to Springer-Verlag, Heidelberg, for the prompt publication of these proceedings and to the Farbwerke Hoechst AG, Frankfurt (M), for their contribution to the printing costs.

New principles for the treatment of diabetes are described in this volume. Experts present experimental and clinical data on treatment with acarbose, an alpha-glucosidase inhibitor that delays absorption of fast carbohydrates. Toxicologic, pharmacologic and metabolic effects of acarbose are discussed. A concluding section on the future aspects of alpha-glucosidase inhibition offers a fair assessment of therapeutic possibilities.

On February 21 and 22, 1975, an International Workshop on the "Genetics of Diabetes Mellitus" was held in Göttingen, West-Germany. This workshop had been organized hy the Department of Medicine, University of Göttingen, and was generously sponsored by the Deutsche Forschungsgemeinschaft. Some forty geneticists and clinicians from Europe and N orth America, working in the field of diabetes both in man and laboratory animals, participated. The 25lectures presented at the workshop are now assembled for publication. Some of the animated discussion which followed the presentations has been included in the final papers by the speakers. Some lectures summarize the recent literature, others present data from recent research. Thus, a comprehensive and modem review of the theoretical and practical problems of diabetes are offered by this volume. related to the genetics The confusion about the mode of inheritance of diabetes mellitus during the last two decades can only be resolved by joint discussions between geneticists interested in diabetes and clinical diabetologists interested in genetics. Knowledge of modem genetics and of the heterogeneity of diabetes mellitus are necessary in order to disentangle the complex scene. Optimistically, the publication of this work on the genetics of diabetes will help to achieve this aim and to establish the concept of genetic heterogeneity of diabetes mellitus. The editors are grateful to Springer-Verlag, Heidelberg, for the prompt publication of these proceedings and to the Farbwerke Hoechst AG, Frankfurt (M), for their contribution to the printing costs.

New principles for the treatment of diabetes are described in this volume. Experts present experimental and clinical data on treatment with acarbose, an alpha-glucosidase inhibitor that delays absorption of fast carbohydrates. Toxicologic, pharmacologic and metabolic effects of acarbose are discussed. A concluding section on the future aspects of alpha-glucosidase inhibition offers a fair assessment of therapeutic possibilities.

Seit der 1. Auflage gab es so wesentliche Neuerungen, vor allem in der Therapie, daß es notwendig war, das Werk fast völlig neu zu konzipieren und zu schreiben. Wie außerordentlich das Wissen in der Gastroenterologie in den letzten Jahren angewachsen ist, zeigt quantitativ der Umfang des Buches. Eigentlich gibt es jetzt keine 2. Auflage, sondern eine annähernd komplette Neukonzeption. Der Begriff "Chirurgische Gastroenterologie" beinhaltet sowohl die gastroenterologische Chirurgie als auch das notwendige Wissen, um eine adäquate Diagnostik und Entscheidungsfindung bei gastroenterologischen Erkrankungen herbeizuführen. Das Buch vermittelt nicht nur das moderne Wissen zur Pathophysiologie und Pathogenese gastroenterologischer Erkrankungen, sondern auch die zielstrebige Diagnostik und Indikationsstellung zur gastroenterologischen Chirurgie. Der interessierte Leser kann alle notwendigen Informationen finden, die zum Verständnis gastroenterologischer Erkrankungen und chirurgischer Entscheidungen notwendig sind - beschrieben von den jeweiligen Kapazitäten. Damit ist das Buch nicht nur für Chirurgen wertvoll, sondern auch für Gastroenterologen und Internisten, die sich über die chirurgischen Möglichkeiten bei Erkrankungen des Verdauungstrakts informieren möchten. Auch Vertreter anderer an der Behandlung gastroenterologischer Erkrankungen beteiligten Disziplinen wie Röntgenologie, Strahlentherapie, Nuklearmedizin, Onkologie etc. finden wesentliche Informationen.

On February 21 and 22, 1975, an International Workshop on the "Genetics of Diabetes Mellitus" was held in Göttingen, West-Germany. This workshop had been organized hy the Department of Medicine, University of Göttingen, and was generously sponsored by the Deutsche Forschungsgemeinschaft. Some forty geneticists and clinicians from Europe and N orth America, working in the field of diabetes both in man and laboratory animals, participated. The 25lectures presented at the workshop are now assembled for publication. Some of the animated discussion which followed the presentations has been included in the final papers by the speakers. Some lectures summarize the recent literature, others present data from recent research. Thus, a comprehensive and modem review of the theoretical and practical problems of diabetes are offered by this volume. related to the genetics The confusion about the mode of inheritance of diabetes mellitus during the last two decades can only be resolved by joint discussions between geneticists interested in diabetes and clinical diabetologists interested in genetics. Knowledge of modem genetics and of the heterogeneity of diabetes mellitus are necessary in order to disentangle the complex scene. Optimistically, the publication of this work on the genetics of diabetes will help to achieve this aim and to establish the concept of genetic heterogeneity of diabetes mellitus. The editors are grateful to Springer-Verlag, Heidelberg, for the prompt publication of these proceedings and to the Farbwerke Hoechst AG, Frankfurt (M), for their contribution to the printing costs.

New principles for the treatment of diabetes are described in this volume. Experts present experimental and clinical data on treatment with acarbose, an alpha-glucosidase inhibitor that delays absorption of fast carbohydrates. Toxicologic, pharmacologic and metabolic effects of acarbose are discussed. A concluding section on the future aspects of alpha-glucosidase inhibition offers a fair assessment of therapeutic possibilities.