Walmor C. De Mello – författare
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11 produkter
11 produkter
E-bok
PDF, Engelska, 20052 167 kr
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Recent studies have shown that the heart possesses an intrinsic renin angiotensin system that is controlled by tissue-specific parameters that are activated by biomechanical stress. This book reviews the latest information on the way in which both the plasma and cardiac renin angiotensin systems affect heart function.
It covers the cell and molecular biology of these systems, with contributions on renin synthesis, uptake and the intracellular signalling pathways. Particular insight comes from transgenic mouse models in which either mouse or human genes for various components of the renin angiotensin system are expressed. Other topics covered include wound healing as well as the trophic effects of aldosterone.
Contains the most recent findings on the renin angiotensin system and the heart Written by an international team of distinguished scientists Covers both the cellular and molecular basis of the renin angiotensin system and the clinical relevance of this research
Inbunden, Engelska, 1997
1 671 kr
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In Heart Cell Communication in Health and Disease an extensive review of different aspects of heart cell communication is presented. The book starts with the fundamental concept that cardiac cells are communicated, and then proceeds to the role of gap junctions in heart development, the molecular biology of gap junctions, the biophysics of the intercellular channels, the control of junctional conductance and the influence of gap junctions on impulse propagation. This is the first time that a single volume has described cell communication in the normal heart and under different pathological conditions such as heart failure, coronary disease, myocardial ischemia and cardiac arrhythmias. In this way the process of cell communication is analyzed at different levels of complexity, providing the reader with a wide view of this field and its relevance to cardiology.
Del 79 - Studies in Linguistics and Philosophy
Speech Acts, Mind, and Social Reality
Discussions with John R. Searle
Inbunden, Engelska, 2002
1 084 kr
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Speech Acts, Mind, and Social Reality - these are the main topics in the work of John R. Searle, one of the leading philosophical figures of the present times. How language is based on intentionality, how intentionality in turn is to be explicated by means of distinctions discovered in Speech Act Theory, and how language and intentionality are both related to social facts and institutions - these are questions to be tackled in this volume. The contributions result from discussions on and with John R. Searle, containing Searle's own latest views - including his seminal ideas on Rationality in Action. The collection provides a good basis for advanced seminar debates in Philosophy of Language, Philosophy of Mind, and Social Philosophy, and will also stimulate some further research on all of the three main topics.
Inbunden, Engelska, 2002
1 671 kr
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Heart Cell Coupling and Impulse Propagation in Health and Disease includes an up-to-date review on how heart cells communicate and impulse propagation under normal as well as under pathological conditions. The complexity of intercellular coupling and impulse propagation is discussed, providing the reader with a broad view of the importance of these processes and how they contribute to the generation of cardiac arrhythmias and heart failure. The different aspects and intricacies of heart cell communication is discussed by different authors, each one an expert in their own field. The present publication will be of interest to cardiologists, electrophysiologists, heart physiologists, cardiac pharmacologists, biophysicists, and cell or molecular biologists.
Häftad, Engelska, 2011
546 kr
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Grau. teurer Freund. ist aUe Theorie Und griln des Lebens goldner Baum All theory. dear friend. is gray But the golden tree of actual life springs ever green -Goethe Progress achieved in the last 25 years indicates that the establishment of inter- cellular junctions at the area of cell contact represents an important mechanism of intercellular communication. Evidence is available that intercellular channels are essential for electrical synchronization in excitable tissues and for the diffusion of molecules from cell to cell. This process of cell-to-cell communication is so reliable that it was pre- served throughout the evolutionary scale. As evolution generates diversity it is not surprising that gap junctions are not the same in all systems. It is known, for 2 instance, that junctional permeability is reduced by high free [Ca +]j in some cells or by a fall in pHi in others, or enhanced by cAMP. Our knowledge of the physiological modulators of junctional permeability is still scanty. Moreover, the compartmentalization of the intracellular milieu represents an additional complication in the interpretation of many studies of cell-to-cell communication.The present volume represents an effort to provide the reader with an actualized view of the mechanisms of cell communication and of the physiologi- cal and pathological implications of junctional and nonjunctional communica- tion. Let us hope that the content of this book helps future studies in establishing a better picture of the cellular and molecular mechanisms involved in the process of intercellular communication.
E-bok
PDF, Engelska, 2012687 kr
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Häftad, Engelska, 2012
1 671 kr
Skickas inom 10-15 vardagar
Heart Cell Coupling and Impulse Propagation in Health and Disease includes an up-to-date review on how heart cells communicate and impulse propagation under normal as well as under pathological conditions. The complexity of intercellular coupling and impulse propagation is discussed, providing the reader with a broad view of the importance of these processes and how they contribute to the generation of cardiac arrhythmias and heart failure. The different aspects and intricacies of heart cell communication is discussed by different authors, each one an expert in their own field. The present publication will be of interest to cardiologists, electrophysiologists, heart physiologists, cardiac pharmacologists, biophysicists, and cell or molecular biologists.
Häftad, Engelska, 2012
1 671 kr
Skickas inom 10-15 vardagar
In Heart Cell Communication in Health and Disease an extensive review of different aspects of heart cell communication is presented. The book starts with the fundamental concept that cardiac cells are communicated, and then proceeds to the role of gap junctions in heart development, the molecular biology of gap junctions, the biophysics of the intercellular channels, the control of junctional conductance and the influence of gap junctions on impulse propagation. This is the first time that a single volume has described cell communication in the normal heart and under different pathological conditions such as heart failure, coronary disease, myocardial ischemia and cardiac arrhythmias. In this way the process of cell communication is analyzed at different levels of complexity, providing the reader with a wide view of this field and its relevance to cardiology.
E-bok
PDF, Engelska, 20122 036 kr
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Heart Cell Coupling and Impulse Propagation in Health and Disease includes an up-to-date review on how heart cells communicate and impulse propagation under normal as well as under pathological conditions. The complexity of intercellular coupling and impulse propagation is discussed, providing the reader with a broad view of the importance of these processes and how they contribute to the generation of cardiac arrhythmias and heart failure. The different aspects and intricacies of heart cell communication is discussed by different authors, each one an expert in their own field. The present publication will be of interest to cardiologists, electrophysiologists, heart physiologists, cardiac pharmacologists, biophysicists, and cell or molecular biologists.
E-bok
PDF, Engelska, 20122 110 kr
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In Heart Cell Communication in Health and Disease an extensive review of different aspects of heart cell communication is presented. The book starts with the fundamental concept that cardiac cells are communicated, and then proceeds to the role of gap junctions in heart development, the molecular biology of gap junctions, the biophysics of the intercellular channels, the control of junctional conductance and the influence of gap junctions on impulse propagation. This is the first time that a single volume has described cell communication in the normal heart and under different pathological conditions such as heart failure, coronary disease, myocardial ischemia and cardiac arrhythmias. In this way the process of cell communication is analyzed at different levels of complexity, providing the reader with a wide view of this field and its relevance to cardiology.
E-bok
PDF, Engelska, 2013807 kr
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Electrical Phenomena in the Heart is a collection of articles that deals with cell physiology and biophysics as applicable to the heart. The book discusses the ultrastructure of heart cells, molecular arrangement of heart cell membranes, and the mechanism involved in sealing and excitation-contraction coupling. The selection describes electrophysiological studies made of embryonic heart cells to understand electrical activity, automaticity, enzyme activities, and the development of intracellular tubular systems. The text also discusses the mechanism of excitation spread between active and inactive cells. The book analyzes the structure of biological membranes and the effect of proteins on membrane potential and on the excitability process. One paper reviews the excitation process of heart cells that includes the use of a voltage clamp in cardiac preparations, as well as the role of the pacemaker. One paper examines the repolarization process involved in cardiac muscle involving the ionic composition and the kinetic properties of membrane currents, as well as the action of some drugs. The book also describes the healing process in cardiac and other muscle fibers when the heart muscle is injured. The text explains that damage to other cardiac muscle can result because of a sealing process that occurs at or near the injured site. The book also explains the model for controlling sarcoplasmic calcium concentration on a single sarcomere level in a mammalian heart. The text can prove significant to students learning heart physiology and biophysics, heart surgeons, and bio-physiologists involved in cellular research.