Walter Thiel – författare

This is currently the only book available on the development of knowledge-based, and related, expert systems in chemistry and toxicology. Written by a pioneer in the field, it shows how computers can work with qualitative information where precise numerical methods are not satisfactory. An underlying theme is the current concern in society about the conflicts between basing decisions on reasoned judgements and wanting precise decisions and measurable effectiveness. As well as explaining how the computer programs work, the book provides insights into how personal and political factors influence scientific progress. The introduction of regulations such as REACH in Europe and modifications to UN and OECD Guidelines on assessment of chemical hazard mean that the use of toxicity prediction is at a turning point. They put a heavy burden on the chemical industry but, for the first time, allow for the use of computer prediction to support or replace in vivo and in vitro experiments. There is increasing recognition among scientists and regulators that qualitative computer methods have much to offer and that in some circumstances they may be more reliable and informative than quantitative methods. This excellent introduction to a field where employment opportunities are growing is aimed at students, scientists and academics with a knowledge of chemistry.

Ions are ubiquitous in chemical, technological, ecological and biological processes. Characterizing their role in these processes in the first place requires the evaluation of the thermodynamic parameters associated with the solvation of a given ion. However, due to the constraint of electroneutrality, the involvement of surface effects and the ambiguous connection between microscopic and macroscopic descriptions, the determination of single-ion solvation properties via both experimental and theoretical approaches has turned out to be a very difficult and highly controversial problem. This unique book provides an up-to-date, compact and consistent account of the research field of single-ion solvation thermodynamics that has over one hundred years of history and still remains largely unsolved. By reviewing the various approaches employed to date, establishing the relevant connections between single-ion thermodynamics and electrochemistry, resolving conceptual ambiguities, and giving an exhaustive data compilation (in the context of alkali and halide hydration), this book provides a consistent synthesis, in depth understanding and clarification of a large and sometimes very confusing research field. The book is primarily aimed at researchers (professors, postgraduates, graduates, and industrial researchers) concerned with processes involving ionic solvation properties (these are ubiquitous, eg. in physical/organic/analytical chemistry, electrochemistry, biochemistry, pharmacology, geology, and ecology). Because of the concept definitions and data compilations it contains, it is also a useful reference book to have in a university library. Finally, it may be of general interest to anyone wanting to learn more about ions and solvation. Key features: - discusses both experimental and theoretical approaches, and establishes the connection between them - provides both an account of the past research (covering over one hundred years) and a discussion of current directions (in particular on the theoretical side) - involves a comprehensive reference list of over 2000 citations - employs a very consistent notation (including table of symbols and unambiguous definitions of all introduced quantities) - provides a discussion and clarification of ambiguous concepts (ie. concepts that have not been defined clearly, or have been defined differently by different authors, leading to confusion in past literature) - encompasses an exhaustive data compilation (in the restricted context of alkali and halide hydration), along with recommended values (after critical analysis of this literature data) - is illustrated by a number of synoptic colour figures, that will help the reader to grasp the connections between different concepts in one single picture

Die brillanten Fotos von Walter Thiel sind einzigartig. Sie revolutionieren die makroskopische Anatomie, denn durch ein neuartiges Konservierungsverfahren behalten alle Gewebe ihre natürliche Farbe und Konsistenz. Die Präparate geben somit erstmals die wirkliche Form der Organe und die wahren räumlichen Verhältnisse wieder. Die hervorragenden Fotos der minutiösen Sektionen sind Kunstwerke von grosser Aussagekraft. Bei dieser Darstellung der topografischen Anatomie werden neben chirurgischen Zugangswegen auch die Funktionen der Gelenke in unübertroffener Detailtreue dokumentiert. Der Atlas ist somit nicht nur für Anatomen und Pathologen von Interesse, sondern auch für chirurgisch tätige Ärzte und alle, deren Arbeit eine räumliche Vorstellung der menschlichen Anatomie erfordert.

In the Preface to the first volume of the Photographic Atlas of Practical Anatomy, we explained our special interpretation of the structure of the superficial fascia of the hu­ man body. The second volume of the Atlas retains this concept and further substanti­ ates its validity. The order in which the anatomic regions are presented may seem unconventional, but it is intended to reflect the importance of"transitional regions" in understanding ana­ tomic relationships. Wherever possible, regions that border one another are presented in sequence. Additionally, we wanted the format of the second volume to follow that of the first, so the joints are placed at the end of the book and the preceding pages are de­ voted to the upper limb. We start with the neck, as it provides a logical transition to the head. The nuchal region serves the same function for the back, which, as part of the thoracic cage, forms a gate­ way to the lateral and anterior chest wall and finally to the upper limbs, which original­ ly developed from the torso as ventral buds. A photographic presentation, more than any other, is bound to reflect individual varia­ tions. This is not necessarily a disadvantage, and we hope that our approach will serve to "flesh out" general and abstract principles. Our reference list covers only works that relate directly to the second volume. Other sources may be found by consulting the more comprehensive bibliography and preface ofVolume I.

Walter Thiel''s brilliant photographs are unique. They revolutionize macroscopic anatomy because - due to a new preservation technique developed by the author himself - all tissues retain their living colour, consistency and position. For the first time anatomical sites show the real colour and form of human organs as well as their true positions. Thiel''s new technique, his exceptional abilities as a photographer and the filigree dissections add up to vivid, almost artistic illustrations of great depth and clarity.Apart from the topographical anatomy of abdomen and lower extremities, Part I illustrates the most important punctures of joints and some surgical approaches. Thus, this atlas is not only of interest to anatomists and pathologists, but particularly to surgeons and orthopaedic surgeons.

Die exzellenten Photos von Walter Thiel erregen Aufsehen. Ein vom Autor entwickeltes neuartiges Konservierungverfahren ermöglicht nicht gekannte optische Dimensionen. Entstanden sind Präparate, die durch ihre Natürlichkeit bestechen. Erstmals werden Organe in ihrer wahren Konsistenz, ihrer natürlichen Verlagerungsmöglichkeit dargestellt. Die hervorragenden Photos der minuziös präparierten Sektionen sind Kunstwerke von großer Aussagekraft. Bei dieser Darstellung der topographischen Anatomie werden neben den für die Chirurgie wichtigen Zugängen auch die Punktionen der Gelenke in unübertroffener Detailtreue dokumentiert. Der Atlas ist somit nicht nur für Anatomen von Interesse, sondern für operativ tätige Ärzte und alle, deren Arbeit eine räumliche Vorstellung der menschlichen Anatomie erfordert.