Zhenhua Li - Böcker

Biomedical Applications of Extracellular Vesicles Unique resource focusing on biomedical applications and clinical translation of extracellular vesicles in science and medicine Focusing on key points to better understand extracellular vesicles (EVs) and their development, Biomedical Applications of Extracellular Vesicles describes in detail the biogenesis of EVs, the mechanism of intercellular communication, and the treatment of various diseases of EVs and the EV-based drug delivery platforms. An application-oriented resource, the work presents rapidly newer biomedical and clinical applications of natural and engineered EVs such as drug delivery, diagnosis, prognosis monitoring, immunotherapy, and more. The first part of this book provides a basic background on EVs. Next, the book introduces the excellent therapeutic effects of EVs themselves and the underlying mechanisms, followed by how EVs from different sources were used to construct drug delivery platforms. The latest research on EVs from leading groups around the world is presented. Sample topics covered in Biomedical Applications of Extracellular Vesicles include: Biogenesis of various EVsPros and cons of the different instrumental and methodological developments for analytical strategies applied to EVsEVs in treatment of major diseases, such as cancer, cardiovascular and respiratory diseasesCurrent methods of engineering EVs, and a comparison of the advantages and disadvantages of each methodBiomaterials, such as hydrogels, scaffolds, and microneedles, that have been developed to further enhance the therapeutic efficacy of EVsKey challenges, such as quality control, scalability, and biosafety, that limit the clinical and industrial translation of EVsExplaining in detail how extracellular vesicles are produced and engineered, along with potential applications and commercial developments of EVs in science and industry, Biomedical Applications of Extracellular Vesicles is an essential resource on the subject for chemists, cell biologists, and molecular physicists.

VolumesofLNCS 5821andCCIS51aretheproceedingsofthe 4thInternational Symposium on Intelligence Computation and Applications (ISICA 2009) held in Huangshi, China, October 23-25, 2009. These two volumes are in memory of Prof. Lishan Kang, the ISICA 2009 Honorary General Chair, who was a leading ?gurein the ?elds of domain decomposition methods and computational intelligence. ISICA 2009 successfully attracted over 300 submissions. Through rigorous reviews, 58 high-quality papers were included in LNCS 5821, while the other 54 papers were collected in CCIS 51. ISICA conferencesare one of the ?rst series of internationalconferencesoncomputationalintelligencethatcombineelementsof learning, adaptation, evolution and fuzzy logic to create programsas alternative solutions to arti?cial intelligence. The last three ISICA proceedings have been accepted in the Index to Scienti?c and Technical Proceedings (ISTP) and/or Engineering Information (EI). Following the success of the past three ISICA events, ISICA 2009 made good progress in the analysis and design of newly developed methods in the ?eld of computationalintelligence.ISICA 2009featured the most up-to-dateresearchin analysisandtheoryofevolutionaryalgorithms,neuralnetworkarchitecturesand learning, fuzzy logic and control, predictive modeling for robust classi?cation, swarm intelligence, evolutionary system design, evolutionary image analysis and signal processing, and computational intelligence in engineering design. ISICA 2009 provided a venue to foster technical exchanges, renew everlasting frie- ships, and establish new connections.

VolumesofLNCS 5821andCCIS51aretheproceedingsofthe 4thInternational Symposium on Intelligence Computation and Applications (ISICA 2009) held in Huangshi, China, October 23-25, 2009. These two volumes are in memory of Prof. Lishan Kang, the ISICA 2009 Honorary General Chair, who was a leading ?gurein the ?elds of domain decomposition methods and computational intelligence. ISICA 2009 successfully attracted over 300 submissions. Through rigorous reviews, 58 high-quality papers were included in LNCS 5821, while the other 54 papers were collected in CCIS 51. ISICA conferencesare one of the ?rst series of internationalconferencesoncomputationalintelligencethatcombineelementsof learning, adaptation, evolution and fuzzy logic to create programsas alternative solutions to arti?cial intelligence. The last three ISICA proceedings have been accepted in the Index to Scienti?c and Technical Proceedings (ISTP) and/or Engineering Information (EI). Following the success of the past three ISICA events, ISICA 2009 made good progress in the analysis and design of newly developed methods in the ?eld of computationalintelligence.ISICA 2009featured the most up-to-dateresearchin analysisandtheoryofevolutionaryalgorithms,neuralnetworkarchitecturesand learning, fuzzy logic and control, predictive modeling for robust classi?cation, swarm intelligence, evolutionary system design, evolutionary image analysis and signal processing, and computational intelligence in engineering design. ISICA 2009 provided a venue to foster technical exchanges, renew everlasting frie- ships, and establish new connections.

This book constitutes the refereed proceedings of the 6th International Symposium on Intelligence Computation and Applications, ISICA 2012, held in Wuhan, China, in October 2012. The 72 revised full papers presented were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on artificial life, adaptive behavior, agents, and ant colony optimization; combinatorial and numerical optimization; communications and computer networks; data mining; evolutionary multi-objective and dynamic optimization; intelligent computation, intelligent learning systems; neural networks; real-world applications.

This book investigates the cloud-based techniques of content distribution mainly for mobile Internet. Lastly, it includes an educational and experimental cloud computing platform allowing public access, which benefits researchers, practitioners, and developers in the field of cloud computing/storage and mobile Internet.

Content distribution, i.e., distributing digital content from one node to another node or multiple nodes, is the most fundamental function of the Internet.

Content distribution, i.e., distributing digital content from one node to another node or multiple nodes, is the most fundamental function of the Internet.