"In conclusion, and to get back to the culinary metaphor (which rang a chord with me as a French reader), it seems that reading this book could be likened to a good appetizer - it should stimulate students to be curious about the rest of the meal and, therefore, run off and read up on the individual aspects of the story." Genevieve Almouzni, Journal of Cell Science, June 2002 "...probably the most informative, carefully thought-out and well-written book on the subject ... invaluable not only to the undergraduate and postgraduate level students for whom it is written, but also for the chromatin community at large. In a fast-growing and ever-expanding field such as the field of chromatin research, such a book will be a rich source of reference for years to come." J Zlatanova, Heredity (2002) 89, 401 "Chromatin and Gene Regulation offers a concise yet intellectually critical introduction to ... gene regulation." Science, April 2003 "[The] gentle progression through the many levels of gene regulation makes this difficult subject easy to understand. The book can easily be read cover to cover, while the clear chapter layout allows students to dip in at any point. This book is ideal for students and researchers wishing to learn more about this rapidly developing subject." Lindsay Emerson, University of Essex, Newsletter of the British Society for Cell Biology, Summer 2003

• Prologue. . 1. Controlling transcription: shared aims and common mechanisms. . 2. Transcription in eukaryotes: the problems of complexity. . 3. The nucleosome: chromatin's structural unit. . 4. Histone tails: modifications and epigenetic information. . 5. Higher-order chromatin structures and nuclear organisation. . 6. Transcription in a chromatin environment. . 7. How the transcription machinery deals with chromatin. . 8. Chromatin remodelling machines. . 9. Heterochromatin. . 10. Long-term silencing of gene expression. . 11. Cellular memory and imprinting. . 12. Mechanisms of dosage compensation

"In conclusion, and to get back to the culinary metaphor (which rang a chord with me as a French reader), it seems that reading this book could be likened to a good appetizer - it should stimulate students to be curious about the rest of the meal and, therefore, run off and read up on the individual aspects of the story." Genevieve Almouzni, Journal of Cell Science, June 2002 "...probably the most informative, carefully thought-out and well-written book on the subject ... invaluable not only to the undergraduate and postgraduate level students for whom it is written, but also for the chromatin community at large. In a fast-growing and ever-expanding field such as the field of chromatin research, such a book will be a rich source of reference for years to come." J Zlatanova, Heredity (2002) 89, 401 "Chromatin and Gene Regulation offers a concise yet intellectually critical introduction to ... gene regulation." Science, April 2003 "[The] gentle progression through the many levels of gene regulation makes this difficult subject easy to understand. The book can easily be read cover to cover, while the clear chapter layout allows students to dip in at any point. This book is ideal for students and researchers wishing to learn more about this rapidly developing subject." Lindsay Emerson, University of Essex, Newsletter of the British Society for Cell Biology, Summer 2003

• Prologue. . 1. Controlling transcription: shared aims and common mechanisms. . 2. Transcription in eukaryotes: the problems of complexity. . 3. The nucleosome: chromatin's structural unit. . 4. Histone tails: modifications and epigenetic information. . 5. Higher-order chromatin structures and nuclear organisation. . 6. Transcription in a chromatin environment. . 7. How the transcription machinery deals with chromatin. . 8. Chromatin remodelling machines. . 9. Heterochromatin. . 10. Long-term silencing of gene expression. . 11. Cellular memory and imprinting. . 12. Mechanisms of dosage compensation