Proteomics

Name: Proteomics
Brand: Springer-Verlag New York Inc.
Price: 2782 SEK
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Biomedical and Pharmaceutical Applications

AvHubert Hondermarck

Springer-Verlag New York Inc.

2004

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Beskrivning

Human biology has now entered into a phase of post-genomics and it might not be an exaggeration to say that the major outcome of the human genome sequencing has finally been to open the way to the exploration of the proteome-proteomics.

Proteins are the functional output of genes and there are two main expected outcomes from human proteomics. The first is to discover new molecular markers for early diagnosis and profiling of pathologies. The second is to decipher the intracellular signaling pathways leading to the initiation and progression of pathologies, for the identification of new targets and the development of innovative therapeutic strategies. This is clearly a promising challenge that this book explores through a series of ongoing experiences and projects representative of the new era in which biology and medicine have now entered.

Produktinformation

Märke:Springer-Verlag New York Inc.
Utgivningsdatum:2004-06-01
Språk:Engelska
Förlag:Springer-Verlag New York Inc.
EAN:9781402023231

Utforska kategorier

Biokemi inom Naturvetenskap och teknik

Innehållsförteckning

Preface. Part One: General principles. Introductory comment; Applied surgical anatomy: intra-abdominal contents; Applied surgical anatomy: pelvic contents; Applied surgical anatomy: perineal and anal canal; Rectal biopsy; Sepsis prevention in colorectal surgery; Patient positioning for colorectal surgery; Anastomotic suturing techniques; Stapling in colorectal surgery; Biodegradable anastomotic ring (BAR) technique; Surgical management of anastomotic leakage and abdominal sepsis; Interventional radiology in colorectal surgery; Operating on the immunosuppressed colorectal patient. Part Two: Endoscopy and laparoscopic techniques. Introductory comment; Proctoscopy and sigmoidoscopy; Colonoscopy and polypectomy; Intraoperative endoscopy; Lasers in colorectal surgery; Basic laparoscopy and instrumentation; Laparoscopic-assisted appendicectomy; Laparoscopic-assisted left hemicolectomy; Laparoscopic-assisted anterior resection and abdominoperineal resection of the rectum; Endoscopic endoluminal rectal tumour resection. Part Three: Stomas. Introductory comment; Ileostomy; Tube caecostomy; Colostomy; Trephine stomas; Complications of ileostomy and colostomy. Part Four: Small bowel surgery. Introductory comment; Resection of the small intestine for inflammatory bowel disease; Small bowel irradiation injury: prevention and management; Intestinal stricturoplasty; Small bowel tumours. Part Five: Intra-abdominal colonic surgery. Introductory comment; Open appendicectomy; Conventional colectomy; Colectomy for malignant disease of the colon: the 'no touch' isolation technique; Elective surgery for sigmoid diverticular disease; Colonic surgery for acute conditions: perforated diverticular disease; Colonic surgery for acute conditions: obstruction; Colonic surgery for acute conditions: massive haemorrhage; Colonic surgery for acute conditions: volvulus of the colon; Colonic surgery for acute conditions: injuries to the intra-abdominal colon; Colonic surgery for acute conditions: amoebiasis. Part Six: Pelvic and rectal surgery. Introductory comment; Anterior resection of the rectum; Abdominoperineal excision of the rectum; Hartmann's operation; Endoabdominal pull-through resection with colorectal-anal anastomosis; Panproctocolectomy and ileostomy; Pelvic exenteration and other extended operations; Extended operations with lateral pelvic dissection of lymph nodes in advanced low rectal cancer; Posterior approach to the rectum (parasacral technique); Anorectal injury; Peranal endorectal operative techniques; Fulguration of malignant rectal tumours. Part Seven: Pouch procedures. Introductory comment; Continent ileostomy (reservoir ileostomy); Kock pouch ileoanal anastomosis; Ileoanal anastomosis with ileal reservoir: S pouch; Ileoanal anastomosis with ileal reservoir: J pouch; Ileoanal anastomosis with ileal reservoir: W pouch; Ileoanal anastomosis with ileal reservoir: H pouch; Management of failed pelvic pouch procedures; Excision of the rectum with colonic J pouch-anal anastomosis. Part Eight: Procedures for rectal prolapse. Introductory comment; Rectal prolapse: intra-abdominal repair with or without resection; Rectal prolapse: rectopexy with synthetic circular net (Ripstein's operation); Rectal prolapse: abdominal rectopexy with posterior fixation; Rectal prolapse: Loygue operation; Rectal prolapse: perineal approach (Delorme operation); Rectal prolapse; Gant-Miwa operation; Rectal prolapse: perineal rectosigmoidectomy with levatoroplasty. Part Nine: Surgery for anal incontinence. Introductory comment; Postanal pelvic floor repair for anal incontinence; Surgical repair of anal sphincters following injury; Pelvic floor descent; Construction of an electrically stimulated gracilis neoanal sphincter; Artificial anal sphincter. Part Ten: Anorectal conditions. Introductory comment; Evacuation and excision of perianal haematoma; Management of uncomplicated internal haemorrhoids; Open haemorrhoidectomy (St Mark's ligation/excision method); Closed haemorrhoidectomy; Circumferential anoplasty: modified Whitehead haemorrhoidectomy; Management of acute anorectal sepsis; Low and fistula; High and fistula; Rectovaginal fistula: endorectal advancement flap; Rectovaginal fistula: vaginal repair; Anal cancer; Lateral subcutaneous internal anal sphincterotomy for anal fissure; Mucosal prolapse; Anoplasty; Perianal and anal condylomata acuminata; Procedures for pilonidal disease; List of products; Index.