Visar resultat för..."sonia matts"

I Gynekologi förmedlar ett stort antal av landets främsta specialister de grundläggande kunskaperna i ämnet liksom undersökning, diagnostik och handläggning av olika gynekologiska tillstånd. Boken tar fasta på vikten av kritisk granskning av medicinska och kirurgiska åtgärder så att medicinska prioriteringar kan göras på bästa möjliga evidens.Nya upplagan av Gynekologi, speglar den enorma utveckling som skett under de senaste fem åren inom kvinnosjukvården. Flera helt nya kapitel har tillkommit vilka innehåller de senaste behandlingsalternativen och ny lagstiftning, framför allt inom reproduktionsmedicin. Tillkommit har också nya förbättrade behandlingsmetoder av cancersjukdomar som inneburit att vissa patientgrupper blivit friska. Detta ställer i sin tur, för god livskvalitet, krav på bättre behandlingsstrategier. Alla bokens kapitel är genomgående uppdaterade med det senaste när det gäller diagnostik och behandling.Boken vänder sig till studerande på läkarutbildningen samt till yrkesverksamma läkare, barnmorskor och sjuksköterskor inom såväl öppen som sluten vård. Den kan även användas som fördjupnings- och referensbok för läkare under specialistutbildning.

An authoritative textbook based on the legendary economics course taught at the University of Chicago—now fully updated and expandedPrice theory is a powerful analytical tool kit for measuring, explaining, and predicting market outcomes. This expanded second edition of Chicago Price Theory offers a unique approach to the subject, emphasizing hands-on, practical applications that can help students adeptly integrate economic theory with real-world forces. A key distinction is its focus on market equilibrium and gains from trade. Unlike many microeconomics texts, this book emphasizes how, through markets, households and businesses adapt to conditions like price controls and externalities. It modernizes the Marshallian idea of forward-falling supply, especially for analyzing human capital, and makes use of the cost function and Hicks-Marshall laws to analyze a variety of economic phenomena. Rooted in Chicago’s price theory tradition, this textbook enables students to understand human behavior through the lens of price theory, showing how a small set of well-mastered tools makes it possible to analyze a remarkably wide range of economic questions.Now includes a full chapter closely integrating economic reasoning with the treatment-control paradigmCovers topics such as occupational choice, the evolution of inequality, the value of a statistical life, prohibition, and competitionUses the economics of “nudges” to understand business contracts and the organization of civil societyFeatures analysis of business-to-business transactionsDiscusses the future implications of artificial intelligenceComes with lesson plans for minicourses in industrial organization, health economics, macroeconomics, labor, public finance, and urban economicsAccompanied by video lectures taught by Kevin M. Murphy, Gary Becker, Casey B. Mulligan, and Robert Minton

Photochemistry of Heterocycles is a comprehensive review of the topic, including photooxidation, photoreduction and photoaddition reactions as well as industrial aspects of heterocyclic photochemistry. Many materials used for the manufacturing of OLEDs and other electrooptical switches contain heterocycles, and the use of small molecules or polymers containing heterocyclic substances are being studied as new photovoltaic materials. This reference is ideal for synthetic organic chemists, specifically researchers working in organic photochemistry, as well as medicinal chemists and material scientists.

Heterocyclic compounds are widely used in the modern world, and most of the drugs currently in use have heterocyclic nuclei among their constituents. These compounds are subject to a photochemical degradation processes which must be known and prevented.

Presents an authoritative and comprehensive review of the photochemistry of heterocycles Covers the full spectrum of photochemical reactivity, including photoreduction and photoaddition reactions of heterocyclic compounds Includes industrial aspects of heterocyclic photochemistry and materials used to manufacture OLEDs and other electrooptical switches

Photochemistry of Heterocycles is a comprehensive review of the topic, including photooxidation, photoreduction and photoaddition reactions as well as industrial aspects of heterocyclic photochemistry. Many materials used for the manufacturing of OLEDs and other electrooptical switches contain heterocycles, and the use of small molecules or polymers containing heterocyclic substances are being studied as new photovoltaic materials. This reference is ideal for synthetic organic chemists, specifically researchers working in organic photochemistry, as well as medicinal chemists and material scientists.Heterocyclic compounds are widely used in the modern world, and most of the drugs currently in use have heterocyclic nuclei among their constituents. These compounds are subject to a photochemical degradation processes which must be known and prevented.- Presents an authoritative and comprehensive review of the photochemistry of heterocycles- Covers the full spectrum of photochemical reactivity, including photoreduction and photoaddition reactions of heterocyclic compounds- Includes industrial aspects of heterocyclic photochemistry and materials used to manufacture OLEDs and other electrooptical switches

Over the past decade, advances in both molecular developmental biology and evolutionary ecology have made possible a new understanding of organisms as dynamic systems interacting with their environments. This innovative book synthesizes a wealth of recent research findings to examine how environments influence phenotypic expression in individual organisms (ecological development or ''eco-devo''), and how organisms in turn alter their environments (niche construction). A key argument explored throughout the book is that ecological interactions as well as natural selection are shaped by these dual organism-environment effects. This synthesis is particularly timely as biologists seek a unified contemporary framework in which to investigate the developmental outcomes, ecological success, and evolutionary prospects of organisms in rapidly changing environments. Organism and Environment is an advanced text suitable for graduate level students taking seminar courses in ecology, evolution, and developmental biology, as well as academics and researchers in these fields.

Over the past decade, advances in both molecular developmental biology and evolutionary ecology have made possible a new understanding of organisms as dynamic systems interacting with their environments. This innovative book synthesizes a wealth of recent research findings to examine how environments influence phenotypic expression in individual organisms (ecological development or ''eco-devo''), and how organisms in turn alter their environments (niche construction). A key argument explored throughout the book is that ecological interactions as well as natural selection are shaped by these dual organism-environment effects. This synthesis is particularly timely as biologists seek a unified contemporary framework in which to investigate the developmental outcomes, ecological success, and evolutionary prospects of organisms in rapidly changing environments. Organism and Environment is an advanced text suitable for graduate level students taking seminar courses in ecology, evolution, and developmental biology, as well as academics and researchers in these fields.

Recent progress in the field of wildlife disease ecology demonstrates that infectious disease plays a crucial role in the lives of wild animals. Parasites and pathogens should be especially important for social animals in which high contact among individuals increases the potential for disease spread. As one of the best studied mammalian groups, primates offer a unique opportunity to examine how complex behaviours (including social organization) influence the risk ofacquiring infectious diseases, and the defences used by animals to avoid infection. This book explores the correlates of disease risk in primates, including not only social and mating behaviour but also diet, habitat use, life history, geography and phylogeny. The authors examine how a core set ofhost and parasite traits influence patterns of parasitism at three levels of biological organization: among individuals, among populations, and across species.A major goal is to synthesize, for the first time, four disparate areas of research: primate behavioural ecology, parasite biology, wildlife epidemiology, and the behavioural and immune defences employed by animals to counter infectious disease. Throughout, the authors provide an overview of the remarkable diversity of infectious agents found in wild primate populations. Additional chapters consider how knowledge of infectious diseases in wild primates can inform efforts focused on primateconservation and human health. More generally, this book identifies infectious disease as an important frontier in our understanding of primate behaviour and ecology. It highlights future challenges for testing the links between host and parasite traits, including hypotheses for the effects of diseaseon primate social and mating systems.

We live in a world teeming with parasites. Many animal behaviors, including social interactions, mating displays, and decisions about where to move, nest, and forage are shaped by interactions with parasites. The same is true for humans, where our attraction to mates, hygienic behaviors, food choices, and decisions about when and where to gather in groups often depend on current and perceived infection risk. In turn, behaviors like social distancing and self-medication can alter the trajectories of parasite transmission and evolution, as vividly illustrated by the ongoing COVID-19 pandemic. The myriad connections between animal behavior and parasitism have been the subject of growing research interest since the 1970s and 80s, when fundamental theories linking the two fields of study emerged. Since then, a combination of conceptual and technological advances, and increased integration of ideas across disciplines, have helped to uncover fascinating new connections between animal behavior and the ecology and evolution of infectious diseases. This accessible text surveys emerging research in this vibrant field. Chapters focus on fundamental topics at the interface of animal behavior and parasitism, and authors have been selected to provide a diverse and international perspective. Animal Behavior and Parasitism is an upper-level text suitable for senior undergraduate and graduate level students as well as professional researchers in animal behavior/behavioral ecology, disease ecology, parasitology, and evolutionary biology.

We live in a world teeming with parasites. Many animal behaviors, including social interactions, mating displays, and decisions about where to move, nest, and forage are shaped by interactions with parasites. The same is true for humans, where our attraction to mates, hygienic behaviors, food choices, and decisions about when and where to gather in groups often depend on current and perceived infection risk. In turn, behaviors like social distancing and self-medication can alter the trajectories of parasite transmission and evolution, as vividly illustrated by the ongoing COVID-19 pandemic. The myriad connections between animal behavior and parasitism have been the subject of growing research interest since the 1970s and 80s, when fundamental theories linking the two fields of study emerged. Since then, a combination of conceptual and technological advances, and increased integration of ideas across disciplines, have helped to uncover fascinating new connections between animal behavior and the ecology and evolution of infectious diseases. This accessible text surveys emerging research in this vibrant field. Chapters focus on fundamental topics at the interface of animal behavior and parasitism, and authors have been selected to provide a diverse and international perspective. Animal Behavior and Parasitism is an upper-level text suitable for senior undergraduate and graduate level students as well as professional researchers in animal behavior/behavioral ecology, disease ecology, parasitology, and evolutionary biology.

Recent progress in the field of wildlife disease ecology demonstrates that infectious disease plays a crucial role in the lives of wild animals. Parasites and pathogens should be especially important for social animals in which high contact among individuals increases the potential for disease spread. As one of the best studied mammalian groups, primates offer a unique opportunity to examine how complex behaviours (including social organization) influence the risk of acquiring infectious diseases, and the defences used by animals to avoid infection. This book explores the correlates of disease risk in primates, including not only social and mating behaviour but also diet, habitat use, life history, geography and phylogeny. The authors examine how a core set of host and parasite traits influence patterns of parasitism at three levels of biological organization: among individuals, among populations, and across species. A major goal is to synthesize, for the first time, four disparate areas of research: primate behavioural ecology, parasite biology, wildlife epidemiology, and the behavioural and immune defences employed by animals to counter infectious disease. Throughout, the authors provide an overview of the remarkable diversity of infectious agents found in wild primate populations. Additional chapters consider how knowledge of infectious diseases in wild primates can inform efforts focused on primate conservation and human health. More generally, this book identifies infectious disease as an important frontier in our understanding of primate behaviour and ecology. It highlights future challenges for testing the links between host and parasite traits, including hypotheses for the effects of disease on primate social and mating systems.

Over the past decade, advances in both molecular developmental biology and evolutionary ecology have made possible a new understanding of organisms as dynamic systems interacting with their environments. This innovative book synthesizes a wealth of recent research findings to examine how environments influence phenotypic expression in individual organisms (ecological development or 'eco-devo'), and how organisms in turn alter their environments (niche construction). A key argument explored throughout the book is that ecological interactions as well as natural selection are shaped by these dual organism-environment effects. This synthesis is particularly timely as biologists seek a unified contemporary framework in which to investigate the developmental outcomes, ecological success, and evolutionary prospects of organisms in rapidly changing environments. Organism and Environment is an advanced text suitable for graduate level students taking seminar courses in ecology, evolution, and developmental biology, as well as academics and researchers in these fields.

Over the past decade, advances in both molecular developmental biology and evolutionary ecology have made possible a new understanding of organisms as dynamic systems interacting with their environments. This innovative book synthesizes a wealth of recent research findings to examine how environments influence phenotypic expression in individual organisms (ecological development or 'eco-devo'), and how organisms in turn alter their environments (niche construction). A key argument explored throughout the book is that ecological interactions as well as natural selection are shaped by these dual organism-environment effects. This synthesis is particularly timely as biologists seek a unified contemporary framework in which to investigate the developmental outcomes, ecological success, and evolutionary prospects of organisms in rapidly changing environments. Organism and Environment is an advanced text suitable for graduate level students taking seminar courses in ecology, evolution, and developmental biology, as well as academics and researchers in these fields.

Business Statistics is a student-friendly book written to encourage first year business students to understand (and enjoy!) their first experience of statistics. Each topic is well illustrated, with worked examples, tutorial sheets, supplementary exercises, and computer worksheets in SPSS, Minitab and Excel - all with answers provided.Accompanying online resources for this title can be found at bloomsburyonlineresources.com/business-statistics-2e. These resources are designed to support teaching and learning when using this textbook and are available at no extra cost.

The state-space approach provides a formal framework where any result or procedure developed for a basic model can be seamlessly applied to a standard formulation written in state-space form. Moreover, it can accommodate with a reasonable effort nonstandard situations, such as observation errors, aggregation constraints, or missing in-sample values.Exploring the advantages of this approach, State-Space Methods for Time Series Analysis: Theory, Applications and Software presents many computational procedures that can be applied to a previously specified linear model in state-space form. After discussing the formulation of the state-space model, the book illustrates the flexibility of the state-space representation and covers the main state estimation algorithms: filtering and smoothing. It then shows how to compute the Gaussian likelihood for unknown coefficients in the state-space matrices of a given model before introducing subspace methods and their application. It also discusses signal extraction, describes two algorithms to obtain the VARMAX matrices corresponding to any linear state-space model, and addresses several issues relating to the aggregation and disaggregation of time series. The book concludes with a cross-sectional extension to the classical state-space formulation in order to accommodate longitudinal or panel data. Missing data is a common occurrence here, and the book explains imputation procedures necessary to treat missingness in both exogenous and endogenous variables.Web ResourceThe authors’ E4 MATLAB® toolbox offers all the computational procedures, administrative and analytical functions, and related materials for time series analysis. This flexible, powerful, and free software tool enables readers to replicate the practical examples in the text and apply the procedures to their own work.

Science in the Study of Ancient Egypt takes an innovative and integrated approach to the use of scientific techniques and methodologies within the study of ancient Egypt. Accessibly demonstrating how to integrate scientific methodologies into Egyptology broadly, and in Egyptian archaeology in particular, this volume will help to maximise the amount of information that can be obtained within a study of ancient Egypt, be it in the field, museum, or laboratory.Using a range of case studies which exemplify best practice within Egyptian archaeological science, Science in the Study of Ancient Egypt presents both the scientific methods of analysis available and their potential applications to Egyptologists. Although Egyptology has mainly shown a marked lack of engagement with recent archaeological science, the authors illustrate the inclusive but varied nature of the scientific archaeology which is now being undertaken, demonstrating how new analytical techniques can develop greater understanding of Egyptian data.

State space models have gained tremendous popularity in recent years in as disparate fields as engineering, economics, genetics and ecology. After a detailed introduction to general state space models, this book focuses on dynamic linear models, emphasizing their Bayesian analysis. Whenever possible it is shown how to compute estimates and forecasts in closed form; for more complex models, simulation techniques are used. A final chapter covers modern sequential Monte Carlo algorithms.The book illustrates all the fundamental steps needed to use dynamic linear models in practice, using R. Many detailed examples based on real data sets are provided to show how to set up a specific model, estimate its parameters, and use it for forecasting. All the code used in the book is available online.No prior knowledge of Bayesian statistics or time series analysis is required, although familiarity with basic statistics and R is assumed.

State space models have gained tremendous popularity in recent years in as disparate fields as engineering, economics, genetics and ecology. After a detailed introduction to general state space models, this book focuses on dynamic linear models, emphasizing their Bayesian analysis. Whenever possible it is shown how to compute estimates and forecasts in closed form; for more complex models, simulation techniques are used. A final chapter covers modern sequential Monte Carlo algorithms.

The book illustrates all the fundamental steps needed to use dynamic linear models in practice, using R. Many detailed examples based on real data sets are provided to show how to set up a specific model, estimate its parameters, and use it for forecasting. All the code used in the book is available online.

No prior knowledge of Bayesian statistics or time series analysis is required, although familiarity with basic statistics and R is assumed.

Becoming a Successful Teacher of Maths is a practical guide for newly qualified teachers of secondary mathematics. It develops the essential core knowledge, skills and understanding demanded by the new DfEE requirements for courses of initial teacher training. It is based on research findings relating to the organisation and management of maths classrooms, teaching approaches, assessment and the common misconceptions which often hinder pupils' progress in key areas of the National Curriculum. Theoretical principles are exemplified through case-study material. Suggestions for school-based activities are made. While being a practical 'how to' guide for beginning teachers, it also offers critical insights for more experienced teachers reflecting on their practice.

Science in the Study of Ancient Egypt takes an innovative and integrated approach to the use of scientific techniques and methodologies within the study of ancient Egypt. Accessibly demonstrating how to integrate scientific methodologies into Egyptology broadly, and in Egyptian archaeology in particular, this volume will help to maximise the amount of information that can be obtained within a study of ancient Egypt, be it in the field, museum, or laboratory.Using a range of case studies which exemplify best practice within Egyptian archaeological science, Science in the Study of Ancient Egypt presents both the scientific methods of analysis available and their potential applications to Egyptologists. Although Egyptology has mainly shown a marked lack of engagement with recent archaeological science, the authors illustrate the inclusive but varied nature of the scientific archaeology which is now being undertaken, demonstrating how new analytical techniques can develop greater understanding of Egyptian data.

This book is designed to give students rapid and easy access to key ecological material to assist learning and revision. Key topics such as populations and interactions, ecosystems, population genetics, community patterns and many more are structured into manageable sections, each cross-referenced, to allow easy navigation through the information.

This book encompasses the most updated and recent account of research and implementation of Microbial Electrochemical Technologies (METs) from pioneers and experienced researchers in the field who have been working on the interface between electrochemistry and microbiology/biotechnology for many years. It provides a holistic view of the METs, detailing the functional mechanisms, operational configurations, influencing factors governing the reaction process and integration strategies. The book not only provides historical perspectives of the technology and its evolution over the years but also the most recent examples of up-scaling and near future commercialization, making it a must-read for researchers, students, industry practitioners and science enthusiasts.

Key Features:

Introduces novel technologies that can impact the future infrastructure at the water-energy nexus. Outlines methodologies development and application of microbial electrochemical technologies and details out the illustrations of microbial and electrochemical concepts. Reviews applications across a wide variety of scales, from power generation in the laboratory to approaches. Discusses techniques such as molecular biology and mathematical modeling; the future development of this promising technology; and the role of the system components for the implementation of bioelectrochemical technologies for practical utility. Explores key challenges for implementing these systems and compares them to similar renewable energy technologies, including their efficiency, scalability, system lifetimes, and reliability.

This book encompasses the most updated and recent account of research and implementation of Microbial Electrochemical Technologies (METs) from pioneers and experienced researchers in the field who have been working on the interface between electrochemistry and microbiology/biotechnology for many years. It provides a holistic view of the METs, detailing the functional mechanisms, operational configurations, influencing factors governing the reaction process and integration strategies. The book not only provides historical perspectives of the technology and its evolution over the years but also the most recent examples of up-scaling and near future commercialization, making it a must-read for researchers, students, industry practitioners and science enthusiasts.

Key Features:

Introduces novel technologies that can impact the future infrastructure at the water-energy nexus. Outlines methodologies development and application of microbial electrochemical technologies and details out the illustrations of microbial and electrochemical concepts. Reviews applications across a wide variety of scales, from power generation in the laboratory to approaches. Discusses techniques such as molecular biology and mathematical modeling; the future development of this promising technology; and the role of the system components for the implementation of bioelectrochemical technologies for practical utility. Explores key challenges for implementing these systems and compares them to similar renewable energy technologies, including their efficiency, scalability, system lifetimes, and reliability.

Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding.

Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran.

Adopts an interdisciplinary approach across biochemistry, molecular biology, pharmaceutical sciences and drug delivery, and biotechnological perspectives Features accessible figures, tables and graphical abstracts across all chapters to support understanding Examines various polysaccharides of current interest and aspects affecting their absorption, metabolism, excretion and detection

Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding.Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran.- Adopts an interdisciplinary approach across biochemistry, molecular biology, pharmaceutical sciences and drug delivery, and biotechnological perspectives- Features accessible figures, tables and graphical abstracts across all chapters to support understanding- Examines various polysaccharides of current interest and aspects affecting their absorption, metabolism, excretion and detection

Micronanoplastics: From Source to Sink: Interactions, Behavior, and Implications on the Environment covers the urgent issue of pollution caused by micronanoplastics (MNP) on the physiochemical and biological properties of soil, water, and air. Through evaluation and analysis of the latest studies, the authors present the effects of micronanoplastics on climate change and offer sustainable alternatives that mitigate the harmful environmental effects. With the help of diagrams and illustrations of models, pathways and processes, the book will provide the researcher and student a deeper understanding of the topics discussed and offer management strategies that promote sustainability.Covers the latest research on the impact of microplastics in the freshwater ecosystemIncludes case studies highlighting recent technologies and interventions for reducing emissions of micronanoplasticsOffers sustainable manufacturing and actionable solutions that address climate change

Micronanoplastics: From Source to Sink: Interactions, Behavior, and Implications on the Environment covers the urgent issue of pollution caused by micronanoplastics (MNP) on the physiochemical and biological properties of soil, water, and air. Through evaluation and analysis of the latest studies, the authors present the effects of micronanoplastics on climate change and offer sustainable alternatives that mitigate the harmful environmental effects. With the help of diagrams and illustrations of models, pathways and processes, the book will provide the researcher and student a deeper understanding of the topics discussed and offer management strategies that promote sustainability. - Covers the latest research on the impact of microplastics in the freshwater ecosystem- Includes case studies highlighting recent technologies and interventions for reducing emissions of micronanoplastics- Offers sustainable manufacturing and actionable solutions that address climate change

Understanding the Pandemic: Pathophysiology, Transmission, and Treatment of COVID-19 aims to cover all aspects of COVID-19 infection from the virus, transmission, pathogenesis, immune-inflammation response, systemic injury, organ damage and associated factors comorbidities that drive mortality. Treatment protocols and the vaccination paradigm will also be discussed.Organized into ten sections, the book aims to provide a comprehensive examination of the impact of COVID-19. The book begins a review of coronaviruses, their structure and mechanism of action. The book goes on to discuss the immune response to the virus and its effect on various organs. It examines clinical cases based on an observations and postmortem studies. Other topics include the long-term effects of COVD-19, vaccines, and public health response.• Discusses coronavirus, their similarities and differences in origin and transmission as well as a review of their structure and mechanisms of action• Examines the immune-inflammation responses to COVID-19 and the organ-specific impact of the disease• Covers vaccines and other treatment protocols and public health responses in various geographic locations