Biomaterials, Bioengineering and Sustainability – serie

The book provides a comprehensive exploration of sustainable practices in biomaterial development for biomedical applications, covering diverse topics such as green synthesis methods, the potential of biodegradable materials, renewable resources for biopolymers, strategies in polymer synthesis, bio-mediated nanomaterials, sustainable manufacturing techniques including 3D and 4D printing, protein-based biomaterials, composite biomaterials derived from cellulose, chitin, and chitosan, as well as hydroxyapatite-starch-based biomaterials, carbonaceous materials, eco-friendly synthesis of metal and metal oxide nanomaterials, silk fibroin scaffold synthesis, utilization of green catalysts, cellulose-derived hydrogels for tissue engineering, plant extract-mediated synthesis of metallic nanoparticles, and eggshell-derived biomaterial synthesis. This multifaceted approach addresses the pressing need for environmentally conscious solutions in the field of biomedical engineering, offering insights into the synthesis, properties, and applications of sustainable biomaterials. This book provides a comprehensive understanding of biodegradable materials, offering a valuable asset for researchers and Ph.D. scholars involved in the ever-changing field of sustainable biomedical engineering.

The book provides a comprehensive exploration of sustainable practices in biomaterial development for biomedical applications, covering diverse topics such as green synthesis methods, the potential of biodegradable materials, renewable resources for biopolymers, strategies in polymer synthesis, bio-mediated nanomaterials, sustainable manufacturing techniques including 3D and 4D printing, protein-based biomaterials, composite biomaterials derived from cellulose, chitin, and chitosan, as well as hydroxyapatite-starch-based biomaterials, carbonaceous materials, eco-friendly synthesis of metal and metal oxide nanomaterials, silk fibroin scaffold synthesis, utilization of green catalysts, cellulose-derived hydrogels for tissue engineering, plant extract-mediated synthesis of metallic nanoparticles, and eggshell-derived biomaterial synthesis. This multifaceted approach addresses the pressing need for environmentally conscious solutions in the field of biomedical engineering, offering insights into the synthesis, properties, and applications of sustainable biomaterials. This book provides a comprehensive understanding of biodegradable materials, offering a valuable asset for researchers and Ph.D. scholars involved in the ever-changing field of sustainable biomedical engineering.

The book delves into the realm of biomaterials with a strong focus on sustainability, offering insights into their diverse applications in advanced therapeutics, and, diagnostics. Tackling cutting-edge topics, it explores the latest developments in green biomaterials for biomedical implants and tissue engineering, emphasizing sustainability in nanocomposite synthesis, properties, and applications. The book also addresses the groundbreaking concept of biodegradable and biofriendly transient devices for sustainable monitoring and healing. Further, it highlights the crucial role of biodegradable scaffolds in engineering living tissues and discusses gene-activated matrices for tissue engineering and regenerative medicine. Various chapters delve into specialized applications, such as tissue-engineered cartilage products, green biomaterials for innovative drug delivery, and 3D printed biodegradable metals in orthopedics and stomatology. The book also explores the use of bioresorbable polymers in advancing minimally invasive surgical procedures and customizing medical devices for personalized medicine. Additionally, it sheds light on the integration of nanobioengineered platforms in electrochemical biosensors for disease diagnosis, antimicrobial biomaterials in dental healthcare, silk-based biomaterials for regenerative medicine and drug delivery, and the utilization of plant-derived biomaterials in cardiac tissue repair. This comprehensive volume not only provides a snapshot of the latest advancements in the field but also underscores the pivotal role of green biomaterials in shaping the future of healthcare technologies.

The book delves into the realm of biomaterials with a strong focus on sustainability, offering insights into their diverse applications in advanced therapeutics, and, diagnostics. Tackling cutting-edge topics, it explores the latest developments in green biomaterials for biomedical implants and tissue engineering, emphasizing sustainability in nanocomposite synthesis, properties, and applications. The book also addresses the groundbreaking concept of biodegradable and biofriendly transient devices for sustainable monitoring and healing. Further, it highlights the crucial role of biodegradable scaffolds in engineering living tissues and discusses gene-activated matrices for tissue engineering and regenerative medicine. Various chapters delve into specialized applications, such as tissue-engineered cartilage products, green biomaterials for innovative drug delivery, and 3D printed biodegradable metals in orthopedics and stomatology. The book also explores the use of bioresorbable polymers in advancing minimally invasive surgical procedures and customizing medical devices for personalized medicine. Additionally, it sheds light on the integration of nanobioengineered platforms in electrochemical biosensors for disease diagnosis, antimicrobial biomaterials in dental healthcare, silk-based biomaterials for regenerative medicine and drug delivery, and the utilization of plant-derived biomaterials in cardiac tissue repair. This comprehensive volume not only provides a snapshot of the latest advancements in the field but also underscores the pivotal role of green biomaterials in shaping the future of healthcare technologies.

Nature has developed a diverse of materials, structures, and processes that are highly optimized for various functions. Through the field of biomimicry and bioinspiration, engineers are enhancing their understanding of natural design principles and applying these insights to create complex engineering models across different scales. These innovative approaches are particularly appropriate to address challenges in tissue engineering and regenerative medicine. Natural materials and systems exhibit a diverse array of functions, including but not limited to structural support, signal transduction, charge transfer, self-assembly, self-organization, and self-replication. Consequently, nature’s "solution manual" is remarkably comprehensive. Despite significant advancements, the reconstruction of nature-inspired designs using synthetic materials presents ongoing challenges. As a result, nature and bioinspired materials and architectures have emerged as a paradigm shift within the realm of tissue engineering and regenerative medicine. This comprehensive guide aims to provide scientists with inspiration to address a variety of critical challenges in tissue regeneration by directly applying established design principles. A key focus of this volume is the utilization of bioinspired architectures in tissue engineering. It also emphasizes the development of nature-inspired structures through the integration of novel biological macromolecules, bioinspired polymers and hydrogels, as well as biomimetic ceramics. Furthermore, the text concentrates on the biochemical and biophysical dimensions of bioinspired surface engineering. Both dry-lab and wet-lab methodologies for characterizing nature and bio-inspired materials and structures are also addressed. The publication seeks to promote the development of high-level translational knowledge among both established and emerging scientists.

This book offers a comprehensive view of the creation and use of natural polysaccharides by integrating sustainability, bioengineering, and green materials in a unique way.With an in-depth coverage, it includes a thorough analysis of natural polysaccharides, delving into their synthesis, characteristics, and range of emerging technology applications, as well as guidance to researchers and practitioners who aim to reduce environmental effects by highlighting eco-friendly design concepts and sustainable manufacturing techniques. Highlighting the potential and adaptability of natural polysaccharides, ranging from eco-friendly packaging materials to medicinal innovations such as tissue engineering and drug delivery systems, this book provides useful information on the practical applications of natural polysaccharides in the real world, encouraging creativity and problem solving through case studies and practical examples.

This book aims to summarize progress in the development of sustainable routes for the production of biopolymers and biocomposites for advanced biomedical engineering and pharmaceutical applications. The book will concentrate on the latest developments in the emerging field of lignin valorization which is essentially a waste material from the paper and pulp industry.The first part of the book will provide the reader with a general overview of the current trends in biopolymers for bioengineering and why there is such a large requirement for sustainable practices in the biomedical field. We will set this within the context of the UN sustainable development goals and the urgent need to move away from fossil-based materials to alleviate climate change. The second part of the book will focus on areas with the greatest potential for the deployment of sustainable polymers in medicine examples include sensors, tissue engineering, drug encapsulation, hydrogels etc. The final section of the book will include a life cycle analysis (LCA0 and a technoeconomic assessment of the transition from fossil to sustainable sources of raw materials.

The battle against complex diseases and tissue defects drives innovation in treatment and medical research. The cell membrane plays a fundamental role in biological processes and serves as a promising platform for diagnostic and therapeutic advancements due to its diverse receptors and ligands. Recent advances in bioengineering, synthetic biology, and biomimetic nanotechnology have enabled the development of engineered cell membrane-based platforms, including surface-engineered cells, extracellular vesicles, bacterial membrane vesicles, membrane-coated nanoparticles, and hybrid nanomaterials, offering improved therapeutic and diagnostic potential over their natural counterparts. This book provides a comprehensive exploration of essential cell surfaceome components, detailing state-of-the-art surface engineering strategies and advancements in engineered cells and membrane-based therapeutic nanoplatforms. It examines the transformative applications of these platforms in immune engineering, gastrointestinal disease management, cancer therapy, tissue engineering, circulating tumor cell capture, theranostics, and the treatment of neurodegenerative, inflammatory, and infectious diseases. Significant topics, many at the forefront of scientific research, are examined in depth, allowing academics, clinicians, and biomedical researchers to understand the latest advancements in cell membrane engineering and address unmet clinical needs. Furthermore, this interdisciplinary book is highly relevant to modern healthcare and provides instructional content for graduate students in chemical biology, pharmacology, biomaterials science, biomedical engineering, immune engineering, nanobiotechnology, regenerative medicine, and translational medicine. This book brings together pioneering research to inspire a broad scientific audience and drive innovation in disease monitoring, precision treatment, and biomedical applications.

Biomaterials are substances that are engineered to interact with biological systems for medical and therapeutic purposes. Biomaterial-based additive manufacturing in tissue engineering is a rapidly evolving ­ field with ongoing research and development. As technology advances, it is likely to play a pivotal role in the development of regenerative medicine and personalized healthcare. Biomaterial-based additive manufacturing, also known as 3D bioprinting utilizing biodegradable or bioavailable polymeric materials, is a cutting-edge technology with great potential and promise for tissue engineering and regeneration. This innovative approach combines biomaterial or engineered biomaterials with precise or customized printing to develop a complex three-dimensional structure that mimics the architecture and functionality of native tissues. An important aspect in development of 3D printed products for tissue engineering or regeneration is selection of biomaterials, development of bio inks using those biomaterials, cell integration, customization, vascularization, and biodegradability of the product. Although 3D bioprinting has shown promise in various applications with potential to revolutionize organ transplantation and tissue engineering, there are several challenges such as ensuring proper vascularization, improving the mechanical properties of printed products, and addressing regulatory aspects with ethical consideration. Therefore, in this book emphasis on tissue engineering and regeneration will be presented, which is an interdisciplinary ­ field that aim to restore, repair, or replace damaged or lost biological tissues. Moreover, chapters inform on recent shift in research that indicates a customized fabrication of biodegradable products, the future of tissue engineering and regeneration.

This book aims to provide a concise overview on the relevant research dealing with the design and fabrication methods of novel scaffolds, considering not only the technological challenges, but also the increasingly important sustainability issues. In this context, the vast options of sustainable biomaterials and eco-friendly/green methods for biomaterials synthesis and scaffold’s processing techniques are discussed. Importantly, the recent developments in the field of scaffolds-based strategies for tissue engineering and regenerative medicine applications are also provided.In brief, the book is divided into three main sections comprising 15 chapters, as follows:I - Sustainable scaffold techniques and designs in tissue engineering;  II - Natural materials and eco-wastes used as sacrificial templates; and III - Biomedical applications.It will also provide a concluding section about the Editor’s opinion on the current achievements and future directions of the field.This book includes the contribution of leading and multidisciplinary experts, which will provide a in depth discussion on sustainable scaffolds for biomedical applications, thus serving as an up-to-date reference for a new generation of multidisciplinary students and researchers which aim to consider the sustainability dimension in their research activities.