Sudarshan Singh – författare

Exploring Nanocarriers in Breast Cancer Management comprehensively delves into the realm of nanocarrier systems, which have shown immense potential in the management of breast cancer. The scope of this book encompasses a thorough exploration of various nanocarrier systems, including, amongst others, liposomes, niosomes, and microneedles. It highlights recent advancements in these systems and their promising results in breast cancer treatment. Additionally, the book addresses the crucial aspects of toxicity and regulatory considerations associated with nanocarriers. It aims to provide a foundational understanding of nanocarriers, their unique features, and their significant role in breast cancer management.As breast cancer remains one of the most prevalent forms of cancer today, with no definitive cure currently available, this book is an essential resource for researchers, healthcare professionals, and anyone interested in cutting-edge developments in breast cancer treatment.Explores various, promising nanocarriers and their roles in breast cancer management, providing a comprehensive understanding of their applicationsExamines the regulatory aspects and toxicities associated with different nanocarrier systems, offering valuable insights for researchers and healthcare professionalsHighlights recent advancements in nanocarrier technology, showcasing the latest developments and their potential impact on breast cancer treatment

Exploring Nanocarriers in Breast Cancer Management comprehensively delves into the realm of nanocarrier systems, which have shown immense potential in the management of breast cancer. The scope of this book encompasses a thorough exploration of various nanocarrier systems, including, amongst others, liposomes, niosomes, and microneedles. It highlights recent advancements in these systems and their promising results in breast cancer treatment. Additionally, the book addresses the crucial aspects of toxicity and regulatory considerations associated with nanocarriers. It aims to provide a foundational understanding of nanocarriers, their unique features, and their significant role in breast cancer management.As breast cancer remains one of the most prevalent forms of cancer today, with no definitive cure currently available, this book is an essential resource for researchers, healthcare professionals, and anyone interested in cutting-edge developments in breast cancer treatment. - Explores various, promising nanocarriers and their roles in breast cancer management, providing a comprehensive understanding of their applications- Examines the regulatory aspects and toxicities associated with different nanocarrier systems, offering valuable insights for researchers and healthcare professionals- Highlights recent advancements in nanocarrier technology, showcasing the latest developments and their potential impact on breast cancer treatment

Rational 'Co-Design' of Targeted Anticancer Therapeutics: Integrating Immuno Oncology, Biomaterials, and Translational Systems presents a unified, system level framework that designs molecules, carriers, and delivery pathways concurrently for clinically translatable cancer therapies. The book details how electronic structure, molecular recognition, biomaterial compatibility, immune microenvironment dynamics, and ADMET/AI models integrate into end to end decision frameworks-from in silico prediction to experimental validation and regulatory readiness. Readers gain a pragmatic path to faster, safer translation: case informed guidance, co design checklists, and criteria for affordability, scalability, and sustainability enable researchers and advanced students to move beyond fragmented, sequential development toward robust therapeutic systems.Provides a rational drug-biomaterial co design framework linking molecular properties to carrier selection and delivery strategyIntegrates computational tools (quantum chemistry, MD, ADMET, AI/ML) with experimental validation and decision frameworksAddresses translational realities-toxicity, immunogenicity, regulatory pathways, manufacturing, cost, and sustainability

Excipients are important components of drug formulations, playing a critical role in ensuring the safety, efficacy, and stability of pharmaceutical products. In recent years, there has been a growing demand for advanced drug delivery systems that can improve the bioavailability, targeting, and sustained release of therapeutics. The development of these systems relies heavily not only on excipients but also on the use of processed excipients, which have been specifically designed and engineered to meet the unique challenges and requirements of advanced drug delivery.This new volume provides a comprehensive overview of the state-of-art research on processed excipients and their utilization in fabrication of advanced drug delivery. Beginning with an introduction and overview, the volume covers novel solid dosage forms, pharmaceutical and biomedical applications, nasal drug delivery, ocular drug delivery, transdermal drug delivery, parenteral medication delivery, pharmacokinetics and pharmacodynamics of processed excipients, and much more.

Excipients are important components of drug formulations, playing a critical role in ensuring the safety, efficacy, and stability of pharmaceutical products. In recent years, there has been a growing demand for advanced drug delivery systems that can improve the bioavailability, targeting, and sustained release of therapeutics. The development of these systems relies heavily not only on excipients but also on the use of processed excipients, which have been specifically designed and engineered to meet the unique challenges and requirements of advanced drug delivery.This new volume provides a comprehensive overview of the state-of-art research on processed excipients and their utilization in fabrication of advanced drug delivery. Beginning with an introduction and overview, the volume covers novel solid dosage forms, pharmaceutical and biomedical applications, nasal drug delivery, ocular drug delivery, transdermal drug delivery, parenteral medication delivery, pharmacokinetics and pharmacodynamics of processed excipients, and much more.

Excipients are important components of drug formulations, playing a critical role in ensuring the safety, efficacy, and stability of pharmaceutical products. In recent years, there has been a growing demand for advanced drug delivery systems that can improve the bioavailability, targeting, and sustained release of therapeutics. The development of these systems relies heavily not only on excipients but also on the use of processed excipients, which have been specifically designed and engineered to meet the unique challenges and requirements of advanced drug delivery.This new volume provides a comprehensive overview of the state-of-art research on processed excipients and their utilization in fabrication of advanced drug delivery. Beginning with an introduction and overview, the volume covers novel solid dosage forms, pharmaceutical and biomedical applications, nasal drug delivery, ocular drug delivery, transdermal drug delivery, parenteral medication delivery, pharmacokinetics and pharmacodynamics of processed excipients, and much more.

Biomaterials are substances that are engineered to interact with biological systems for medical and therapeutic purposes. Biomaterial-based additive manufacturing in tissue engineering is a rapidly evolving ­ field with ongoing research and development. As technology advances, it is likely to play a pivotal role in the development of regenerative medicine and personalized healthcare. Biomaterial-based additive manufacturing, also known as 3D bioprinting utilizing biodegradable or bioavailable polymeric materials, is a cutting-edge technology with great potential and promise for tissue engineering and regeneration. This innovative approach combines biomaterial or engineered biomaterials with precise or customized printing to develop a complex three-dimensional structure that mimics the architecture and functionality of native tissues. An important aspect in development of 3D printed products for tissue engineering or regeneration is selection of biomaterials, development of bio inks using those biomaterials, cell integration, customization, vascularization, and biodegradability of the product. Although 3D bioprinting has shown promise in various applications with potential to revolutionize organ transplantation and tissue engineering, there are several challenges such as ensuring proper vascularization, improving the mechanical properties of printed products, and addressing regulatory aspects with ethical consideration. Therefore, in this book emphasis on tissue engineering and regeneration will be presented, which is an interdisciplinary ­ field that aim to restore, repair, or replace damaged or lost biological tissues. Moreover, chapters inform on recent shift in research that indicates a customized fabrication of biodegradable products, the future of tissue engineering and regeneration.

Biomaterials are substances that are engineered to interact with biological systems for medical and therapeutic purposes. Biomaterial-based additive manufacturing in tissue engineering is a rapidly evolving ­ field with ongoing research and development. As technology advances, it is likely to play a pivotal role in the development of regenerative medicine and personalized healthcare. Biomaterial-based additive manufacturing, also known as 3D bioprinting utilizing biodegradable or bioavailable polymeric materials, is a cutting-edge technology with great potential and promise for tissue engineering and regeneration. This innovative approach combines biomaterial or engineered biomaterials with precise or customized printing to develop a complex three-dimensional structure that mimics the architecture and functionality of native tissues. An important aspect in development of 3D printed products for tissue engineering or regeneration is selection of biomaterials, development of bio inks using those biomaterials, cell integration, customization, vascularization, and biodegradability of the product. Although 3D bioprinting has shown promise in various applications with potential to revolutionize organ transplantation and tissue engineering, there are several challenges such as ensuring proper vascularization, improving the mechanical properties of printed products, and addressing regulatory aspects with ethical consideration. Therefore, in this book emphasis on tissue engineering and regeneration will be presented, which is an interdisciplinary ­ field that aim to restore, repair, or replace damaged or lost biological tissues. Moreover, chapters inform on recent shift in research that indicates a customized fabrication of biodegradable products, the future of tissue engineering and regeneration.