Medical Intelligence Unit – serie
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71 produkter
New Bacterial Vaccines
Av Ronald W. Ellis, Bernard R. Brodeur m. fl.
Inbunden, 2003
2091 kr
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New Bacterial Vaccines focuses upon unfulfilled needs for bacterial vaccines. The increase in drug resistance among many bacterial species has increased the need for new bacterial vaccines. This book serves as a comprehensive reference on the major aspects of developing new bacterial vaccines. The …
DNA Methylation and Cancer Therapy
Av Moshe Szyf, Moshe Szyf
Inbunden, 2005
1680 kr
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NA methylation has bewildered molecular biologists since Hotchkiss discovered it almost six decades ago (Hotchkiss RDJ. Biol Cem 1948; 175:315-332). The fact that the chemical structure of our D genome consists of two components that are covalently bound, the genetic information that is replicated …
Molecular Mechanisms of Pathogenesis in Chagas' Disease
Inbunden, 2003
1680 kr
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Chagas' disease, which results from infection with the single cell parasite Trypanosoma cruzi, is a debilitating condition that is a major problem in many parts of Latin America. Rapid technical progress is now facilitating dissection of the molecular mechanisms of disease pathogenesis, a process …
Fibrogenesis
Cellular and Molecular Basis
Inbunden, 2005
1680 kr
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Fibrogenesis: Cellular and Molecular Basis is the first volume to provide a synopsis of the rapid progress that has been documented in fibrogenesis over last couple of years, which significantly enhanced our understanding of the pathomechanisms of fibrotic diseases. Knowledge on molecular and …
Hematopoietic Stem Cell Development
Inbunden, 2006
1680 kr
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Hematopoietic Stem Cells brings together articles covering the biology of hematopoietic stem cells during embryonic development, reporting particular aspects of fly, fish, avian and mammalian models. Thus, this book allows a comparative overview of hematopoietic stem cell generation in the …
MALT Lymphomas
Av Emanuele Zucca, Emanuele Zucca m. fl.
Inbunden, 2004
1122 kr
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MALT Lymphomas is a multidisciplinary book that covers all the aspects of MALT lymphomas, from the molecular biology, the aetiology and the pathology, to all the possible therapeutic approaches. Extranodal marginal zone B cell lymphoma of MALT type (MALT lymphoma) is one of the lymphoma subtypes …
VEGF and Cancer
Inbunden, 2004
899 kr
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"VEGF and Cancer" is a comprehensive and up to date review of current knowledge on the role of vascular endothelial growth factor (VEGF) in cancer. Key features include: discussion of VEGF as potent angiogenic factor and its role in tumor angiogenesis; review of the biology, molecular properties …
Oral Tolerance
Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential
Inbunden, 2004
1631 kr
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Oral tolerance is a major immunological property of the gastrointestinal mucosa. It plays a critical role in immune defence by preventing inflammatory and allergic responses to dietary and non pathogenic microbial antigens. The interest in oral tolerance has been renewed in the recent years, due to …
Gene Therapy of Autoimmune Disease
Inbunden, 2005
1680 kr
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Autoimmune diseases are diverse and responsible for considerable morbidity. Their etiology remains largely unknown, and current therapy with anti-inflammatory drugs is prone to adverse effects, and rarely curative. New therapies with anti-cytokine antibodies or receptors are promising, but require …
Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules
Av Christopher Janson, Matthew During
Inbunden, 2006
1680 kr
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This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic …
Oxidative Phosphorylation in Health and Disease
Inbunden, 2004
1680 kr
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Mitochondrial diseases are often hard to diagnose. From the time they were first researched without animal models, patients of mitochondrial diseases were of equal interest to both clinical and basic scientists. With the new research done, this book includes updates on the normal structure, …
Chemokines in Viral Infections
Inbunden, 2004
1122 kr
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In the past five years, a large number of new chemokines and chemokine receptors have been identified. Alarming progress in the areas of bioinformatics and expressed sequence tag (EST) databases attributed to this development. Recent discoveries provide compelling evidences supporting the roles of …
Marfan Syndrome
A Primer for Clinicians and Scientists
Av Peter N. Robinson, Maurice Godfrey m. fl.
Inbunden, 2004
1680 kr
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Marfan Syndrome is a hereditary disorder of connective tissue which primarily affects the cardiovascular, skeletal, and ocular systems. Remarkable progress in the field has been made in both clinical and basic-science research since the discovery of the gene for fibrillin-1 (FBN1) in 1991, …
Molecular Mechanisms of Phagocytosis
Inbunden, 2005
1683 kr
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Although, Phagocytosis was first described nearly 120 year ago, we are just recently beginning to understand the molecules that phagocytic cells use to bring about this complex cell function. Molecular Mechanisms of Phagocytosis was prepared as a series of up-to-date essays (chapters) that describe …
Lysosomes
Inbunden, 2005
1634 kr
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Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of this organelle is underlined by an increasing number of human diseases, which are associated with an impaired function of the lysosomal compartment.This book summarizes the current state-of-the art …
Molecular Mechanisms of Basal Cell and Squamous Cell Carcinomas
Av Jorg Reichrath, Jörg Reichrath
Inbunden, 2006
1683 kr
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apid progress in the understanding of carcinogenesis and pathology of epitheUal skin cancer has led to new strategies for the prevention Rand treatment of these malignancies. The goal of this volume is to comprehensively cover in a highly readable overview our present knowledge of pathogenetic …
Molecular Mechanisms of Axenfeld-Rieger Syndrome
Inbunden, 2005
1124 kr
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We are excited to bring together recent research on the molecular biology of Axenfeld-Rieger syndrome (ARS) disorders. In the following chapters we will review and provide direct evidence for the molecular basis of this group of heterogeneous disorders, which include Rieger syndrome and Rieger …
Immunology of Pregnancy
Inbunden, 2006
2242 kr
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Reproductive Immunology is a growing area in both immunology and reproductive sciences and is helping us to better understand several complications of pregnancy. Immunology of Pregnancy is the first book to give a complete and up to date review of our knowledge related to the role of the immune …
Molecular Mechanisms of Fanconi Anemia
Inbunden, 2006
1683 kr
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Molecular Mechanisms of Fanconi Anemia will give research students a platform for further investigation, and act as a source of information regarding experimental design. Clinicians will find this title useful for its comprehensive description of Fanconi Anemia and information on the latest …
Fas Signaling
Inbunden, 2006
1634 kr
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Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of …
Rb and Tumorigenesis
Av Maurizio Fanciulli, Maurizio Fanciulli
Inbunden, 2006
1634 kr
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Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in …
Hepatitis Delta Virus
Av Hiroshi Handa, Yuki Yamaguchi
Inbunden, 2006
1124 kr
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Hepatitis Delta Virus is an up-to-date guide to hepatitis D virus (HDV), a human virus with a number of distinctive features. Each chapter of this book describes one of the broad aspects of HDV from virology to molecular biology, and from diagnosis to therapy.
Hyperthermia In Cancer Treatment: A Primer
Av Gian F. Baronzio, E. Dieter Hager
Inbunden, 2006
2465 kr
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Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 …
DNA Repair and Human Disease
Av Adayabalam Balajee, Adayabalam S. Balajee
Inbunden, 2006
1634 kr
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DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
Immunogenetics of Autoimmune Disease
Av Jorge R. Oksenberg, David Brassat
Inbunden, 2006
1683 kr
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utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion …
Mechanisms of Insulin Action
Av Alan R. Saltiel, Jeffrey E. Pessin
Inbunden, 2007
1683 kr
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More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the …
Immunosenescence
Inbunden, 2008
1683 kr
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Human immunosenescence contributes to morbidity and mortality in later life. The age-associated increasing incidence of cancer and cardiovascular disease plateaus at around 80 years of age in industrialised countries, but death due to infectious disease continues to increase up to 100 years of age …
Mechanisms of Insulin Action
Av Alan R. Saltiel, Jeffrey E. Pessin
Häftad, 2011
1692 kr
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More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the …
Immunosenescence
Häftad, 2010
1692 kr
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Human immunosenescence contributes to morbidity and mortality in later life. The age-associated increasing incidence of cancer and cardiovascular disease plateaus at around 80 years of age in industrialised countries, but death due to infectious disease continues to increase up to 100 years of age …
DNA Methylation and Cancer Therapy
Av Moshe Szyf
Häftad, 2010
1671 kr
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NA methylation has bewildered molecular biologists since Hotchkiss discovered it almost six decades ago (Hotchkiss RDJ. Biol Cem 1948; 175:315-332). The fact that the chemical structure of our D genome consists of two components that are covalently bound, the genetic information that is replicated …
