Resistance to Targeted Anti-Cancer Therapeutics – serie
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40 produkter
Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy
Targeted Therapies to Reverse Resistance
Inbunden, 2013
1693 kr
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This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of …
Resistance to Immunotherapeutic Antibodies in Cancer
Strategies to Overcome Resistance
Inbunden, 2013
1693 kr
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The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encouraging results in alternative therapeutic approach called …
Resistance to Immunotherapeutic Antibodies in Cancer
Strategies to Overcome Resistance
Häftad, 2015
1693 kr
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The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encouraging results in alternative therapeutic approach called …
Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy
Targeted Therapies to Reverse Resistance
Häftad, 2015
1693 kr
Lägg i varukorg
This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of …
Resistance to Ibritumomab in Lymphoma
Av Makoto Hosono, Jean-François Chatal
Häftad, 2019
1128 kr
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This volume, in discussing resistance to ibritumomab, will focus on the mechanism, hematological aspects, radiological and nuclear medicine aspects, and medical physics that deal with radiation dosimetry, and will outline future prospects for overcoming resistance and enhancing efficacy of …
Resistance of Targeted Therapies Excluding Antibodies for Lymphomas
Häftad, 2019
1352 kr
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In the last decade, the literature on molecular mechanisms and activated pathways in the different lymphoma categories increased exponentially, which was followed by a more diffuse and successful use of targeted therapies. In this book, expert authors revisit the most relevant aspects of these …
Cancer Stem Cell Resistance to Targeted Therapy
Av Cristina Maccalli, Matilde Todaro m. fl.
Inbunden, 2019
1128 kr
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This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to …
Cancer Stem Cell Resistance to Targeted Therapy
Av Cristina Maccalli, Matilde Todaro m. fl.
Häftad, 2020
1128 kr
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This book represents an up-dated summary of the state of the art of the characterization of cancer stem cell/ cancer initiating cell (CSC/CIC) properties. An overview of the definition and biological properties of CSCs/CICs as well as the role of these cells in determining the resistance to …
Current Applications for Overcoming Resistance to Targeted Therapies
Av Myron R. Szewczuk, Bessi Qorri m. fl.
2019
1330 kr
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Targeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. …
Current Applications for Overcoming Resistance to Targeted Therapies
Av Myron R. Szewczuk, Bessi Qorri m. fl.
Häftad, 2020
1128 kr
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Targeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. …
Resistance to Targeted Therapies in Lymphomas
Av Ana C. Xavier, Mitchell S. Cairo
Inbunden, 2019
1128 kr
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Over the past few decades, lymphoma patient outcomes have improved as a result of multidrug chemotherapy and radiation therapy, intensification of treatment, improvement in supportive care, and better imaging and staging systems. Even more recently, there has been tremendous progress in the …
Resistance to Targeted Therapies in Lymphomas
Av Ana C. Xavier, Mitchell S. Cairo
Häftad, 2020
1128 kr
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Over the past few decades, lymphoma patient outcomes have improved as a result of multidrug chemotherapy and radiation therapy, intensification of treatment, improvement in supportive care, and better imaging and staging systems. Even more recently, there has been tremendous progress in the …
Resistance to Targeted Therapies in Multiple Myeloma
Av Silvia CW Ling, Steven Trieu
Inbunden, 2021
1576 kr
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Multiple Myeloma remains an incurable malignancy. As the disease progresses, it invariably becomes resistant to treatment and almost all patients develop refractory disease. There are multiple different types of targeted therapies and many of them are used in combination at different stages of …
Resistance to Targeted Therapies in Multiple Myeloma
Av Silvia CW Ling, Steven Trieu
Häftad, 2022
1576 kr
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Multiple Myeloma remains an incurable malignancy. As the disease progresses, it invariably becomes resistant to treatment and almost all patients develop refractory disease. There are multiple different types of targeted therapies and many of them are used in combination at different stages of …
Resistance to Proteasome Inhibitors in Cancer
Molecular Mechanisms and Strategies to Overcome Resistance
Av Q. Ping Dou
Inbunden, 2014
1688 kr
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The book explores cutting-edge strategies to overcome proteasome inhibitor resistance, including the second generation 20S proteasome inhibitors, novel combinational therapies, and new targets in the ubiquitin-proteasome pathway (e.g., ubiquitin E3 ligases, deubiquitinases, 19S proteasomal ATPases, …
Resistance to Targeted ABC Transporters in Cancer
Inbunden, 2014
1128 kr
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This critical review volume explores the theme of ABC transporters in the context of basic cancer research and its role in drug-resistant tumors. The chapters provided complement basic research by including investigations from translational applications to clinical oncology. The development of …
Resistance to Photodynamic Therapy in Cancer
Av Valentina Rapozzi, Giulio Jori
Inbunden, 2015
1128 kr
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This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic …
Resistance to Immunotoxins in Cancer Therapy
Av Rama Shanker Verma, Benjamin Bonavida
Inbunden, 2015
1128 kr
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This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms …
Resistance of Cancer Cells to CTL-Mediated Immunotherapy
Av Benjamin Bonavida, Salem Chouaib
Inbunden, 2015
1128 kr
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This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume …
Resistance to Aromatase Inhibitors in Breast Cancer
Inbunden, 2015
1128 kr
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Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of …
Resistance to Proteasome Inhibitors in Cancer
Molecular Mechanisms and Strategies to Overcome Resistance
Av Q. Ping Dou
Häftad, 2016
1688 kr
Lägg i varukorg
The book explores cutting-edge strategies to overcome proteasome inhibitor resistance, including the second generation 20S proteasome inhibitors, novel combinational therapies, and new targets in the ubiquitin-proteasome pathway (e.g., ubiquitin E3 ligases, deubiquitinases, 19S proteasomal ATPases, …
Resistance to Photodynamic Therapy in Cancer
Av Valentina Rapozzi, Giulio Jori
Häftad, 2016
1128 kr
Lägg i varukorg
This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic …
Resistance to Aromatase Inhibitors in Breast Cancer
Häftad, 2016
1128 kr
Lägg i varukorg
Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of …
Resistance to Immunotoxins in Cancer Therapy
Av Rama Shanker Verma, Benjamin Bonavida
Häftad, 2016
1128 kr
Lägg i varukorg
This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms …
Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
Inbunden, 2016
1128 kr
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This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these …
Resistance to Tyrosine Kinase Inhibitors
Inbunden, 2016
1688 kr
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The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most …
Resistance to Targeted Therapies Against Adult Brain Cancers
Inbunden, 2016
1688 kr
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This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts …
Resistance to Molecular Therapies for Hepatocellular Carcinoma
Inbunden, 2017
1688 kr
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This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including …
TRAIL, Fas Ligand, TNF and TLR3 in Cancer
Inbunden, 2017
1688 kr
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This volume provides the current understanding of death receptor's/TLR3 signaling regulation in cancer. Death receptors, including TRAIL-R1, TRAIL-R2, Fas and TNF-RI, owing to their ability to trigger apoptosis and to contribute to the elimination of cancer cells by the immune system have been …
Resistance to Anti-Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways
Av Yosef Yarden, Moshe Elkabets
Inbunden, 2018
1688 kr
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This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play …
