Translational Oncology – serie
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5 produkter
5 produkter
Del 1 - Translational Oncology
Introduction to Translational Cancer Research
Inbunden, Engelska, 2027
1 832 kr
Kommande
Bridge the gap between laboratory discovery and cancer care and control While molecular understanding of cancer has expanded exponentially, clinical progress has been more gradual. Introduction to Translational Cancer Research provides a primer for new investigators that focuses on accelerating progress in cancer care, detection and control. Written by physician-scientists with combined expertise spanning biomarker discovery, drug development, and cancer prevention, this volume describes the bidirectional flow between laboratory discoveries and clinical and community applications. The book examines how human cancer biology and molecular diagnostics have driven the development of molecular therapeutics, leading to personalized treatment, detection and prevention. Translation across the full spectrum of cancer management is described including medical, surgical, radiation and pediatric oncology as well as cancer imaging. Coverage spans drug and biologics development and the application of AI to accelerate the delivery of new agents with greater efficiency. The inter-related roles of academe, pharma and government are considered. Readers will also find: How our deepening understanding of cancer biology and immunology have informed the development and use of targeted drugs and biologics, individually and in combination.Career development of physician-scientist and members of translational teamsResearch on dissemination of new ideas and agentsImpact of translational research on underserved patientsWays to accelerate progress in cancer research.Clinical and research oncologists, medical students, graduate students and fellows, biomedical scientists, and pharmaceutical professionals will find this a valuable guide for understanding how translational research transforms laboratory discoveries into improved patient and population-level outcomes.
Inbunden, Engelska, 2018
2 320 kr
Skickas inom 5-8 vardagar
A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues.Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapyExplores the breath of treatments that reflect the complexity of the immune system itselfIncludes contributions from a panel international experts in the field of immunotherapyDesigned for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.
Del 5 - Translational Oncology
Targeted Therapy in Translational Cancer Research
Inbunden, Engelska, 2015
1 874 kr
Skickas inom 11-20 vardagar
Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancerCovers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicineSummarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities
Del 3 - Translational Oncology
Biomarkers in Cancer Screening and Early Detection
Inbunden, Engelska, 2017
1 874 kr
Skickas inom 11-20 vardagar
Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkersProvides immediately actionable information and hopefully also inspiration to move discovery and clinical application forwardOffers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers
Del 4 - Translational Oncology
Cancer Gene Therapy by Viral and Non-viral Vectors
Inbunden, Engelska, 2014
1 931 kr
Skickas inom 11-20 vardagar
Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor.This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy.Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in CancerPrinciples of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene TherapyFocusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.