Trends in Drug Discovery – serie

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5 produkter

Del 1 - Trends in Drug Discovery
Trends in mRNA Vaccine Research
AvGabor Tamas Szabo,Gabor Tamas Szabom. fl.
Inbunden, Engelska, 2025
1 849 kr
Skickas inom 5-8 vardagar
The authoritative guide to the revolutionary concept behind the successful Covid-19 vaccines In Trends in mRNA Vaccine Research, a team of distinguished researchers delivers a practical and up-to-date discussion of the biochemical and biomedical foundations of mRNA vaccines. They also explore the manufacturing conditions required for successful vaccine development and review recent progress in a variety of medical fields, including vaccines against pathogens like SARS-CoV-2, HIV, plasmodium, Mycobacterium tuberculosis, as well as anticancer vaccines. Volume highlights include: A historical overview of mRNA vaccine developmentImmune responses to modified or unmodified mRNA vaccinesA description of the different mRNA vaccine platformsLatest data on current mRNA vaccine developments against infectious diseases and cancerPerfect for medicinal chemists, immunologists, and epidemiologists, Trends in mRNA Vaccine Research will also benefit researchers and scientists working in the pharmaceutical industry, as well as cancer researchers with an interest in vaccine development.
Del 2 - Trends in Drug Discovery
Trends in CNS Drug Discovery
AvDario Doller,Dario Dollerm. fl.
Inbunden, Engelska, 2025
1 934 kr
Skickas inom 3-6 vardagar
Provides insights into the drug discovery innovations that are shaping future CNS therapies In the vast field of neuroscience, drug discovery targeting the central nervous system (CNS) presents both extraordinary opportunities and complex challenges. Disorders such as Alzheimer’s disease, schizophrenia, and epilepsy affect millions worldwide, demanding innovative therapeutic strategies. Yet understanding brain processes and overcoming the blood-brain barrier continue to pose significant hurdles for researchers and developers alike. Trends in CNS Drug Discovery offers a comprehensive overview of the methodologies, successes, and challenges shaping this critical area of pharmaceutical research. Covering a wide range of key areas, from current therapeutic paradigms to emerging technologies, this state-of-the-art volume brings together expertise from leading scientists and drug developers who address the role of cannabinoids and psychedelics in advancing CNS therapeutics, discuss emerging modalities such as protein degraders and allosteric modulators, examine funding strategies and academic-industrial collaborations, highlight advancements in brain-penetrating cancer treatments and other high-impact areas, and more. Explores cutting-edge methodologies, including biomarkers, animal models, and brain imaging for CNS drug discoveryReviews innovative therapies such as combination drugs and prodrugs for improved treatment outcomesAnalyzes challenges in targeting diseases including Alzheimer’s and schizophrenia with novel therapeutic strategiesIncludes real-world case studies demonstrating achievements and lessons in CNS drug developmentA critical reference for academic researchers and industry professionals in medicinal chemistry, pharmaceutical research, and neurobiology, Trends in CNS Drug Discovery is also an ideal resource for graduate-level courses in neuroscience or pharmaceutical sciences.
Trends in Antiviral Drug Development
AvMichael J. Sofia,Michael J. Sofiam. fl.
Inbunden, Engelska, 2025
1 695 kr
Skickas
Hard-to-find insights from industry professionals on success strategies for developing the next generation of antiviral blockbuster drugs Presented by industry professionals with a track record of discovering new drugs and treatments, Trends in Antiviral Drug Development describes successful development efforts for antiviral compounds and therapies that have entered the market or are currently in clinical trials. Viruses are ordered by their target tissue, in line with contemporary drug development that focuses on tissue-targeted therapeutics. Other key trends in antiviral therapy, such as the effort to develop long-acting drugs, are described for each virus type, enabling readers to follow the current and future state in this core area of contemporary drug development. Trends in Antiviral Drug Development includes discussion on: Novel drugs against herpes viruses as well as the breakthrough drugs that cured HCVsiRNA therapeutics, a new antiviral modality, and the drug candidates that are progressing toward achieving an HBV cureDrugs targeting viral entry, such as in HIV entry through attachment, co-receptor binding, and fusionNovel therapeutics against tropical diseases such as dengue fever and monkey poxTrends in Antiviral Drug Development is an essential read for medicinal chemists, pharmaceutical chemists, virologists, and all professionals seeking to understand new ideas and approaches to combat the ever-expanding universe of viral infections.
Del 4 - Trends in Drug Discovery
Trends in Drug Discovery in Diabetes and Obesity
AvLars Linderoth,Soren Ostergaard
Inbunden, Engelska, 2026
1 531 kr
Kommande
Drug discovery strategies for next-generation anti-diabetic and anti-obesity therapies Diabetes ranks as the seventh leading cause of death globally, claiming 1.5 million victims annually, yet the complexity of energy metabolism makes pharmaceutical intervention difficult—often requiring simultaneous modulation of multiple drug targets. Trends in Drug Discovery in Diabetes and Obesity assembles drug developers from pharma companies who share hard-to-find insight on strategies for developing more efficient therapies. The book surveys critical drug classes including GLP-1 receptor agonists, GIP antagonists, poly-agonist drugs, and long-acting insulin variants, covering both peptide and small molecule approaches. Selected case studies detail the discovery pathways of recently approved drugs, providing direct insight into the decision-making and optimization processes that led from target identification through clinical validation to market approval. Readers will also find: Reviews of recent therapy developments and emerging treatment paradigms reshaping the current diabetes and obesity pharmacological landscapeEvaluation of poly-agonist drug potential and their projected role in future multi-target therapeutic strategies for metabolic disordersPerspectives from industry professionals across pharmaceutical companies offering practical context rarely available in academic literature aloneCoverage of peptide drug design strategies alongside small molecule approaches for addressing complex metabolic pathway modulation challengesCase studies tracing recently approved drugs from early discovery through optimization, illustrating real-world drug development decision frameworksDesigned for medicinal chemists, pharmaceutical chemists, and endocrinologists working in drug discovery and development, this volume delivers the strategic and mechanistic insight needed to advance the next generation of therapeutics targeting diabetes and obesity across both industry and academic research settings.
Trends in Antibody Drug Discovery for Cancer Therapy
AvChristian Klein,John M. Lambert
Inbunden, Engelska, 2027
1 785 kr
Kommande
Drug developers share strategies for next-generation antibody-based cancer therapeuticsCancer immunotherapy has produced two transformative drug classes: bispecific antibodies and antibody-drug conjugates. Trends in Antibody Drug Discovery for Cancer Therapy brings together drug developers from pharmaceutical companies of all sizes to share their experiences developing these therapeutics. Christian Klein, whose Roche team contributed to twenty-four clinical stage bispecific antibodies, offers key insights into successful strategies for anticancer drug development.This book begins with a review of recent therapy developments in biological cancer treatment before examining bispecific antibodies and antibody-drug conjugates through detailed case studies of recently approved therapeutics. An international team of contributors then examine how bispecific antibodies target both cancer and immune cells, and how antibody-drug conjugates deliver cytotoxic payloads directly to tumors. The final section evaluates emerging approaches including antibody-based PROTACs and cytokine mimetics.Readers will also benefit from: Case studies documenting the development pathways of recently approved bispecific antibodies and antibody-drug conjugates from preclinical research through to clinical applicationAnalysis of targeted protein degradation strategies including antibody-based PROTACs and their potential for harnessing this mechanism in cancer therapyExpert evaluation of cytokine mimetics and other forward-looking approaches contributing to the next generation of antibody-based cancer treatmentsInsights from drug developers at both small and large pharmaceutical companies sharing past successes and future development plansDesigned for medicinal chemists, pharmaceutical chemists, and oncologists working in drug discovery and development, this volume addresses the unmet medical need for more efficient cancer therapeutics. Industry professionals will gain actionable insights for developing antibody-based drugs in a field that leads global pharmaceutical markets.

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Trends in Drug Discovery – serie

Trends in mRNA Vaccine Research

Trends in CNS Drug Discovery

Trends in Antiviral Drug Development

Trends in Drug Discovery in Diabetes and Obesity

Trends in Antibody Drug Discovery for Cancer Therapy

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