Wiley Series on Technologies for the Pharmaceutical Industry – serie

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12 produkter

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12 produkter

Del 3 - Wiley Series on Technologies for the Pharmaceutical Industry
Pathway Analysis for Drug Discovery
Computational Infrastructure and Applications
AvAnton Yuryev
Inbunden, Engelska, 2008
1 621 kr
Skickas inom 5-8 vardagar
This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in related fields.
Del 11 - Wiley Series on Technologies for the Pharmaceutical Industry
Predictive Approaches in Drug Discovery and Development
Biomarkers and In Vitro / In Vivo Correlations
AvJ. Andrew Williams,J. Andrew Williamsm. fl.
Inbunden, Engelska, 2012
1 819 kr
Skickas inom 5-8 vardagar
Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers. Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.
Del 7 - Wiley Series on Technologies for the Pharmaceutical Industry
Pharmaceutical Data Mining
Approaches and Applications for Drug Discovery
AvKonstantin V. Balakin,Sean Ekins
Inbunden, Engelska, 2010
1 997 kr
Skickas inom 11-20 vardagar
Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applicationsChemoinformatics-based applicationsBioinformatics-based applicationsData mining methods in clinical developmentData mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approachesIn one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.
Del 4 - Wiley Series on Technologies for the Pharmaceutical Industry
Drug Efficacy, Safety, and Biologics Discovery
Emerging Technologies and Tools
AvSean Ekins,Jinghai J. Xu
Inbunden, Engelska, 2009
1 855 kr
Skickas inom 11-20 vardagar
Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools covers key emerging technologies in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The cross-disciplinary collaborations implicit in integrating these technologies with drug discovery operations will fuel the engine for future innovations. This book cuts across the multiple areas of drug discovery, each chapter authored by pioneers in that field, making for a broad appeal to the chemical and biological scientists and technologists involved in drug discovery and development.
Del 6 - Wiley Series on Technologies for the Pharmaceutical Industry
Agile Approach to Adaptive Research
Optimizing Efficiency in Clinical Development
AvMichael J. Rosenberg,Sean Ekins
Inbunden, Engelska, 2010
1 182 kr
Skickas inom 5-8 vardagar
Apply adaptive research to improve results in drug development The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently.With a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current practices, and the advantages of adaptive research technology and methods. He explains the concepts, principles, and specific techniques of adaptive research, and demonstrates why it is an essential evolutionary step toward improving drug research and development.Chapters explore such subjects as: The adaptive concept Design and operational adaptations Sample-size reestimation Agile clinical development Safety and dose finding Statistics in adaptive research, including frequentist and Bayesian approaches Data management technologies The future of clinical development By combining centuries-old intellectual foundations, recent technological advances, and modern management techniques, adaptive research preserves the integrity and validity of clinical research but dramatically improves efficiency.
Del 9 - Wiley Series on Technologies for the Pharmaceutical Industry
Systems Biology in Drug Discovery and Development
AvDaniel L. Young,Seth Michelson
Inbunden, Engelska, 2011
1 550 kr
Skickas inom 5-8 vardagar
The first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology in Drug Discovery and Development presents practical applications of systems biology to the multiple phases of drug discovery and development. This book explains how the integration of knowledge from multiple sources, and the models that best represent that integration, inform the drug research processes that are most relevant to the pharmaceutical and biotechnology industries.The first book to focus on comprehensive systems biology and its applications in drug discovery and development, it offers comprehensive and multidisciplinary coverage of all phases of discovery and design, including target identification and validation, lead identification and optimization, and clinical trial design and execution, as well as the complementary systems approaches that make these processes more efficient. It also provides models for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker identification.Introducing and explaining key methods and technical approaches to the use of comprehensive systems biology on drug development, the book addresses the challenges currently facing the pharmaceutical industry. As a result, it is essential reading for pharmaceutical and biotech scientists, pharmacologists, computational modelers, bioinformaticians, and graduate students in systems biology, pharmaceutical science, and other related fields.
Del 8 - Wiley Series on Technologies for the Pharmaceutical Industry
Pharmaceutical and Biomedical Project Management in a Changing Global Environment
AvScott D. Babler
Inbunden, Engelska, 2010
1 423 kr
Skickas inom 5-8 vardagar
Pharmaceutical and Biomedical Portfolio Management in a Changing Global Environment explores some of the critical forces at work today in the complex endeavour of pharmaceutical and medical product development. Written by experienced professionals, and including real-world approaches and best practice examples, this new title addresses three key areas – small molecules, large molecules, and medical devices - and provides hard-to-find, consolidated information relevant to and needed by pharmaceutical, biotech, and medical device company managers.
Del 10 - Wiley Series on Technologies for the Pharmaceutical Industry
Collaborative Computational Technologies for Biomedical Research
AvSean Ekins,Sean Ekinsm. fl.
Inbunden, Engelska, 2011
1 934 kr
Skickas inom 5-8 vardagar
Methods, Processes, and Tools for Collaboration"The time has come to fundamentally rethink how we handle the building of knowledge in biomedical sciences today. This book describes how the computational sciences have transformed into being a key knowledge broker, able to integrate and operate across divergent data types."Bryn Williams-Jones, Associate Research Fellow, PfizerThe pharmaceutical industry utilizes an extended network of partner organizations in order to discover and develop new drugs, however there is currently little guidance for managing information and resources across collaborations.Featuring contributions from the leading experts in a range of industries, Collaborative Computational Technologies for Biomedical Research provides information that will help organizations make critical decisions about managing partnerships, including: Serving as a user manual for collaborations Tackling real problems from both human collaborative and data and informatics perspectives Providing case histories of biomedical collaborations and technology-specific chapters that balance technological depth with accessibility for the non-specialist reader A must-read for anyone working in the pharmaceuticals industry or academia, this book marks a major step towards widespread collaboration facilitated by computational technologies.
Del 12 - Wiley Series on Technologies for the Pharmaceutical Industry
Collaborative Innovation in Drug Discovery
Strategies for Public and Private Partnerships
AvRathnam Chaguturu
Inbunden, Engelska, 2014
1 706 kr
Skickas inom 5-8 vardagar
Can academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the skyrocketing costs and plummeting productivity plaguing R&D, and many key products are facing patent expiration. Dr. Rathnam Chaguturu presents a case for collaboration between the pharmaceutical industry and academia that could reverse the industry's decline. Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships provides insight into the potential synergy of basing R&D in academia while leaving drug companies to turn hits into marketable products. As Founder and CEO of iDDPartners, focused on pharmaceutical innovation, Founding president of the International Chemical Biology Society, and Senior Director-Discovery Sciences, SRI International, Dr. Chaguturu has assembled a panel of experts from around the world to weigh in on issues that affect the two driving forces in medical advancement. Gain global perspectives on the benefits and potential issues surrounding collaborative innovationDiscover how industries can come together to prevent another "Pharma Cliff"Learn how nonprofits are becoming the driving force behind innovationRead case studies of specific academia-pharma partnerships for real-life examples of successful collaborationExplore government initiatives that help foster cooperation between industry and academiaDr. Chaguturu’s thirty-five years of experience in academia and industry, managing new lead discovery projects and forging collaborative partnerships with academia, disease foundations, nonprofits, and government agencies lend him an informative perspective into the issues facing pharmaceutical progress. In Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships, he and his expert team provide insight into the various nuances of the debate.
Del 2 - Wiley Series on Technologies for the Pharmaceutical Industry
Pharmaceutical Applications of Raman Spectroscopy
AvSlobodan Sasic
Inbunden, Engelska, 2007
1 622 kr
Skickas inom 11-20 vardagar
Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data. Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy, provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Applications cover a broad range from discovery to manufacturing in the pharmaceutical industry and include identifying polymorphs, monitoring real-time processes, imaging solid dosage formulations, imaging active pharmaceutical ingredients in cells, and diagnostics.
Computational Toxicology
Risk Assessment for Chemicals
AvSean Ekins
Inbunden, Engelska, 2018
2 111 kr
Skickas inom 11-20 vardagar
A key resource for toxicologists across a broad spectrum of fields, this book offers a comprehensive analysis of molecular modelling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals. Provides a perspective of what is currently achievable with computational toxicology and a view to future developmentsHelps readers overcome questions of data sources, curation, treatment, and how to model / interpret critical endpoints that support 21st century hazard assessmentAssembles cutting-edge concepts and leading authors into a unique and powerful single-source referenceIncludes in-depth looks at QSAR models, physicochemical drug properties, structure-based drug targeting, chemical mixture assessments, and environmental modelingFeatures coverage about consumer product safety assessment and chemical defense along with chapters on open source toxicology and big data
Del 5 - Wiley Series on Technologies for the Pharmaceutical Industry
Engines of Hippocrates
From the Dawn of Medicine to Medical and Pharmaceutical Informatics
AvBarry Robson,O. K. Baekm. fl.
Inbunden, Engelska, 2009
1 216 kr
Tillfälligt slut
A unique, integrative look at information-based medicine The convergence of medical science, biology, pharmacology, biomedical engineering, healthcare, and information technology is revolutionizing medical and scientific practice, and has broader social implications still being understood. The Engines of Hippocrates provides a unique, integrative, and holistic look at the new paradigm of information-based medicine, covering a broad range of topics for a wide readership.The authors take a comprehensive approach, examining the prehistory, history, and future of medicine and medical technology and its relation to information; how history led to such present-day discoveries as the structure of DNA, the human genome, and the discipline of bioinformatics; and what the future results of these discoveries may hold. Their far-ranging views are their own and not necessarily those of the IBM Corporation or other employers.The Engines of Hippocrates helps readers understand: Forces shaping the pharmaceutical and biomedical industries today, including personalized medicine, genomics, data mining, and bionanotechnologyThe relationship between pharmaceutical science today and other disciplines such as philosophy of health, history, economics, mathematics, and computer science The integrated role alternative and non-Western medicines could play in a new, information-based medicine Practical, ethical, organizational, technological, and social problems of information-based medicine, along with a novel data-centric computing model and a self-adaptive software engineering model, and corresponding information technology architectures, including perspectives on sharing remote data efficiently and securely for the common good An unmatched, cross-disciplinary perspective on the big picture of today and tomorrow's medicine, The Engines of Hippocrates provides a reference to interested readers both inside and outside the pharmaceutical and medical communities, as well as a peerless classroom supplement to students in a wide variety of disciplines.

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Wiley Series on Technologies for the Pharmaceutical Industry – serie

Pathway Analysis for Drug Discovery

Predictive Approaches in Drug Discovery and Development

Pharmaceutical Data Mining

Drug Efficacy, Safety, and Biologics Discovery

Agile Approach to Adaptive Research

Systems Biology in Drug Discovery and Development

Pharmaceutical and Biomedical Project Management in a Changing Global Environment

Collaborative Computational Technologies for Biomedical Research

Collaborative Innovation in Drug Discovery

Pharmaceutical Applications of Raman Spectroscopy

Computational Toxicology

Engines of Hippocrates

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