Dr. Nedal Abu-Thabit holds a Ph.D. in chemistry with specialization in polymer chemistry. Currently, Dr. Nedal is an associate professor in the Chemical & Process Engineering Technology department at Jubail Industrial College. Since 2013, he holds the position of the Program Director for Polymer Engineering Technology major. Dr. Nedal has published more than 20 research articles and reviews in refereed journals, 5 book chapters and 2 patents. His research interests in the areas of polymer synthesis, polymer post-functionalization, synthesis of functional polyelectrolytes for fuel cells applications, water sterilization using nanomaterials, synthesis of electrically conducting polymers for sensing applications, preparation of conductive hydrogels and conductive textiles; and isolation of biopolymers from natural sources. In addition, Dr. Nedal has contributed with many articles in the area of educational polymer chemistry. Professor Abdel Salam Hamdy Makhlouf is the Vice President of Integrated Mechanical Material Corrosion Consulting (IM2C), Texas, USA, and a Full professor at Central Metallurgical Research and Development Institute. He has 26 years of experience working in R&D with a blend of both industrial and academic leadership as a Professor of Materials Science, and Advanced “nano-bio” Manufacturing Engineering, and Materials Engineering Consultant. He is the recipient of numerous national and international prizes and awards including the Humboldt Research Award for Experienced Scientists, at Max Planck Institute, Germany; Fulbright, NSF, and Dept. of Energy Fellowships, USA; Shoman Award in Engineering Science; and the State Prize of Egypt in Advanced Science and Technology. His research has focused on five critical areas: Energy, Health, Environment, Advanced manufacturing, Advanced materials. Dr. Makhlouf has published over 200 journal articles, as well as 17 books and handbooks for Springer and Elsevier on a broad range of cross‐disciplinary research fields including advanced multifunctional materials, nanotechnology, smart coatings, corrosion, biomaterials, waste/water treatment, and materials for energy applications. Dr. Makhlouf has served as both a Senior Editor and board member of many international journals, as well as reviewer for several international funding agencies in USA, Germany, UK, Qatar, Belgium, EU, Kazakhstan. He is a Consultant/Reviewer for several universities worldwide.

• Part One: Introduction1. Historical development of drug delivery systems: From conventional macroscale to controlled, targeted, and responsive nanoscale systems2. Stimuli-responsive polymers as smart drug delivery systems: Classifications based on carrier type and triggered-release mechanismPart Two: Endogenous and exogenous stimuli-responsive drug delivery systems3 The smart chemistry of stimuli-responsive polymeric carriers for target drug delivery applications4. Enzyme-responsive polymers for drug delivery and molecular imaging5. pH-responsive polymers for drug delivery applications6. Magnetically responsive polymers for drug delivery applicationsPart Three: Polymeric nanocarriers for stimuli-responsive drug delivery systems7. Responsive block copolymers for drug delivery applications. Part 1: Endogenous stimuli-responsive drug-release systems8. Responsive block copolymers for drug delivery applications. Part 2: Exogenous stimuli-responsive drug-release systems9. Responsive polyelectrolyte multilayer nanofilms for drug delivery applications10. Responsive polyelectrolyte complexes based on natural polysaccharides for drug delivery applications11. Responsive polymer nanoparticles for drug delivery applications12. Stimulus-responsive nanogels for drug delivery13. Stimuli-responsive polymeric hydrogels and nanogels for drug delivery applicationsPart Four: Biopolymer and biodegradable nanocarriers for stimuli-responsive drug delivery systems14. Bioinspired polymeric carriers for drug delivery applications15. Stimuli-responsive biopolymer nanocarriers for drug delivery applications16. Responsive polymer-biomacromolecule conjugates for drug delivery17. Responsive biopolymer-based microgels/nanogels for drug delivery applications18. Stimuli-responsive poly(ε-caprolactone)s for drug delivery applications19. Responsive polysaccharides and polysaccharides-based nanoparticles for drug delivery 20. Responsive cyclodextrins as polymeric carriers for drug delivery applications21. Chitosan as responsive polymer for drug delivery applications22. Biodegradable polyhydroxyalkanoates nanocarriers for drug delivery applications23. Biodegradable polymeric micelles for drug delivery applications

Dr. Nedal Abu-Thabit holds a Ph.D. in chemistry with specialization in polymer chemistry. Currently, Dr. Nedal is an associate professor in the Chemical & Process Engineering Technology department at Jubail Industrial College. Since 2013, he holds the position of the Program Director for Polymer Engineering Technology major. Dr. Nedal has published more than 20 research articles and reviews in refereed journals, 5 book chapters and 2 patents. His research interests in the areas of polymer synthesis, polymer post-functionalization, synthesis of functional polyelectrolytes for fuel cells applications, water sterilization using nanomaterials, synthesis of electrically conducting polymers for sensing applications, preparation of conductive hydrogels and conductive textiles; and isolation of biopolymers from natural sources. In addition, Dr. Nedal has contributed with many articles in the area of educational polymer chemistry. Professor Abdel Salam Hamdy Makhlouf is the Vice President of Integrated Mechanical Material Corrosion Consulting (IM2C), Texas, USA, and a Full professor at Central Metallurgical Research and Development Institute. He has 26 years of experience working in R&D with a blend of both industrial and academic leadership as a Professor of Materials Science, and Advanced “nano-bio” Manufacturing Engineering, and Materials Engineering Consultant. He is the recipient of numerous national and international prizes and awards including the Humboldt Research Award for Experienced Scientists, at Max Planck Institute, Germany; Fulbright, NSF, and Dept. of Energy Fellowships, USA; Shoman Award in Engineering Science; and the State Prize of Egypt in Advanced Science and Technology. His research has focused on five critical areas: Energy, Health, Environment, Advanced manufacturing, Advanced materials. Dr. Makhlouf has published over 200 journal articles, as well as 17 books and handbooks for Springer and Elsevier on a broad range of cross‐disciplinary research fields including advanced multifunctional materials, nanotechnology, smart coatings, corrosion, biomaterials, waste/water treatment, and materials for energy applications. Dr. Makhlouf has served as both a Senior Editor and board member of many international journals, as well as reviewer for several international funding agencies in USA, Germany, UK, Qatar, Belgium, EU, Kazakhstan. He is a Consultant/Reviewer for several universities worldwide.

• Part One: Introduction1. Historical development of drug delivery systems: From conventional macroscale to controlled, targeted, and responsive nanoscale systems2. Stimuli-responsive polymers as smart drug delivery systems: Classifications based on carrier type and triggered-release mechanismPart Two: Endogenous and exogenous stimuli-responsive drug delivery systems3 The smart chemistry of stimuli-responsive polymeric carriers for target drug delivery applications4. Enzyme-responsive polymers for drug delivery and molecular imaging5. pH-responsive polymers for drug delivery applications6. Magnetically responsive polymers for drug delivery applicationsPart Three: Polymeric nanocarriers for stimuli-responsive drug delivery systems7. Responsive block copolymers for drug delivery applications. Part 1: Endogenous stimuli-responsive drug-release systems8. Responsive block copolymers for drug delivery applications. Part 2: Exogenous stimuli-responsive drug-release systems9. Responsive polyelectrolyte multilayer nanofilms for drug delivery applications10. Responsive polyelectrolyte complexes based on natural polysaccharides for drug delivery applications11. Responsive polymer nanoparticles for drug delivery applications12. Stimulus-responsive nanogels for drug delivery13. Stimuli-responsive polymeric hydrogels and nanogels for drug delivery applicationsPart Four: Biopolymer and biodegradable nanocarriers for stimuli-responsive drug delivery systems14. Bioinspired polymeric carriers for drug delivery applications15. Stimuli-responsive biopolymer nanocarriers for drug delivery applications16. Responsive polymer-biomacromolecule conjugates for drug delivery17. Responsive biopolymer-based microgels/nanogels for drug delivery applications18. Stimuli-responsive poly(ε-caprolactone)s for drug delivery applications19. Responsive polysaccharides and polysaccharides-based nanoparticles for drug delivery 20. Responsive cyclodextrins as polymeric carriers for drug delivery applications21. Chitosan as responsive polymer for drug delivery applications22. Biodegradable polyhydroxyalkanoates nanocarriers for drug delivery applications23. Biodegradable polymeric micelles for drug delivery applications

Dr. Nedal Abu-Thabit holds a Ph.D. in chemistry with specialization in polymer chemistry. Currently, Dr. Nedal is an associate professor in the Chemical & Process Engineering Technology department at Jubail Industrial College. Since 2013, he holds the position of the Program Director for Polymer Engineering Technology major. Dr. Nedal has published more than 20 research articles and reviews in refereed journals, 5 book chapters and 2 patents. His research interests in the areas of polymer synthesis, polymer post-functionalization, synthesis of functional polyelectrolytes for fuel cells applications, water sterilization using nanomaterials, synthesis of electrically conducting polymers for sensing applications, preparation of conductive hydrogels and conductive textiles; and isolation of biopolymers from natural sources. In addition, Dr. Nedal has contributed with many articles in the area of educational polymer chemistry. Professor Abdel Salam Hamdy Makhlouf is the Vice President of Integrated Mechanical Material Corrosion Consulting (IM2C), Texas, USA, and a Full professor at Central Metallurgical Research and Development Institute. He has 26 years of experience working in R&D with a blend of both industrial and academic leadership as a Professor of Materials Science, and Advanced “nano-bio” Manufacturing Engineering, and Materials Engineering Consultant. He is the recipient of numerous national and international prizes and awards including the Humboldt Research Award for Experienced Scientists, at Max Planck Institute, Germany; Fulbright, NSF, and Dept. of Energy Fellowships, USA; Shoman Award in Engineering Science; and the State Prize of Egypt in Advanced Science and Technology. His research has focused on five critical areas: Energy, Health, Environment, Advanced manufacturing, Advanced materials. Dr. Makhlouf has published over 200 journal articles, as well as 17 books and handbooks for Springer and Elsevier on a broad range of cross‐disciplinary research fields including advanced multifunctional materials, nanotechnology, smart coatings, corrosion, biomaterials, waste/water treatment, and materials for energy applications. Dr. Makhlouf has served as both a Senior Editor and board member of many international journals, as well as reviewer for several international funding agencies in USA, Germany, UK, Qatar, Belgium, EU, Kazakhstan. He is a Consultant/Reviewer for several universities worldwide.

• Part One: Introduction1. Historical development of drug delivery systems: From conventional macroscale to controlled, targeted, and responsive nanoscale systems2. Stimuli-responsive polymers as smart drug delivery systems: Classifications based on carrier type and triggered-release mechanismPart Two: Endogenous and exogenous stimuli-responsive drug delivery systems3 The smart chemistry of stimuli-responsive polymeric carriers for target drug delivery applications4. Enzyme-responsive polymers for drug delivery and molecular imaging5. pH-responsive polymers for drug delivery applications6. Magnetically responsive polymers for drug delivery applicationsPart Three: Polymeric nanocarriers for stimuli-responsive drug delivery systems7. Responsive block copolymers for drug delivery applications. Part 1: Endogenous stimuli-responsive drug-release systems8. Responsive block copolymers for drug delivery applications. Part 2: Exogenous stimuli-responsive drug-release systems9. Responsive polyelectrolyte multilayer nanofilms for drug delivery applications10. Responsive polyelectrolyte complexes based on natural polysaccharides for drug delivery applications11. Responsive polymer nanoparticles for drug delivery applications12. Stimulus-responsive nanogels for drug delivery13. Stimuli-responsive polymeric hydrogels and nanogels for drug delivery applicationsPart Four: Biopolymer and biodegradable nanocarriers for stimuli-responsive drug delivery systems14. Bioinspired polymeric carriers for drug delivery applications15. Stimuli-responsive biopolymer nanocarriers for drug delivery applications16. Responsive polymer-biomacromolecule conjugates for drug delivery17. Responsive biopolymer-based microgels/nanogels for drug delivery applications18. Stimuli-responsive poly(ε-caprolactone)s for drug delivery applications19. Responsive polysaccharides and polysaccharides-based nanoparticles for drug delivery 20. Responsive cyclodextrins as polymeric carriers for drug delivery applications21. Chitosan as responsive polymer for drug delivery applications22. Biodegradable polyhydroxyalkanoates nanocarriers for drug delivery applications23. Biodegradable polymeric micelles for drug delivery applications