Inbunden, Engelska, 2008

The Spinal Cord

A Christopher and Dana Reeve Foundation Text and Atlas

Av Charles Watson, George Paxinos, Gulgun Kayalioglu

2110 kr

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Beskrivning

Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of nervous tissue in the spine to regenerate has increasingly been on the forefront of biomedical research in the past years. The Spinal Cord, a collaboration with the Christopher and Dana Reeve Foundation, is the first comprehensive book on the anatomy of the mammalian spinal cord. Tens of thousands of articles and dozens of books are published on this subject each year, and a great deal of experimental work has been carried out on the rat spinal cord. Despite this, there is no comprehensive and authoritative atlas of the mammalian spinal cord. Almost all of the fine details of spinal cord anatomy must be searched for in journal articles on particular subjects. This book addresses this need by providing both a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords in one convenient source. The book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations from the leading experts in the field and atlases of the rat and the mouse spinal cord. The rat and mouse spinal cord atlas chapters include photographs of Nissl stained transverse sections from each of the spinal cord segments (obtained from a single unfixed spinal cord), detailed diagrams of each of the spinal cord segments pictured, delineating the laminae of Rexed and all other significant neuronal groupings at each level and photographs of additional sections displaying markers such as acetylcholinesterase (AChE), calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), enkephalin, calcitonin gene-related peptide (CGRP), and neuronal nuclear protein (NeuN).

The text provides a detailed account of the anatomy of the mammalian spinal cord and surrounding musculoskeletal elements
The major topics addressed are: development of the spinal cord; the gross anatomy of the spinal cord and its meninges; spinal nerves, nerve roots, and dorsal root ganglia; the vertebral column, vertebral joints, and vertebral muscles; blood supply of the spinal cord; cytoarchitecture and chemoarchitecture of the spinal gray matter; musculotopic anatomy of motoneuron groups; tracts connecting the brain and spinal cord; spinospinal pathways; sympathetic and parasympathetic elements in the spinal cord; neuronal groups and pathways that control micturition; the anatomy of spinal cord injury in experimental animals
The atlas of the rat and mouse spinal cord has the following features: Photographs of Nissl stained transverse sections from each of 34 spinal segments for the rat and mouse; Detailed diagrams of each of the 34 spinal segments for rat and mouse, delineating the laminae of Rexed and all other significant neuronal groupings at each level. ; Alongside each of the 34 Nissl stained segments, there are additional sections displaying markers such as acetylcholinesterase, calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), and neuronal nuclear protein (NeuN)
All the major motoneuron clusters are identified in relation to the individual muscles or muscle groups they supply

Produktinformation

Utgivningsdatum: 2008-11-12
Mått: 218 x 279 x 28 mm
Vikt: 1 544 g
Format: Inbunden
Språk: Engelska
Antal sidor: 408
Förlag: Elsevier Science
ISBN: 9780123742476

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Mer om författaren

Charles Watson is a neuroscientist and public health physician. His qualifications included a medical degree (MBBS) and two research doctorates (MD and DSc). He is Professor Emeritus at Curtin University, and holds adjunct professorial research positions at the University of New South Wales, the University of Queensland, and the University of Western Australia. He has published over 100 refereed journal articles and 40 book chapters, and has co-authored over 25 books on brain and spinal cord anatomy. The Paxinos Watson rat brain atlas has been cited over 80,000 times. His current research is focused on the comparative anatomy of the hippocampus and the claustrum.He was awarded the degree of Doctor of Science by the University of Sydney in 2012 and received the Distinguished Achievement Award of the Australasian Society for Neuroscience in 2018. George Paxinos has written 62 books on the brain of humans, monkeys, rodents and birds. His first atlas, The Rat Brain in Stereotaxic Coordinates, is the most cited neuroscience publication. His Atlas of the Human Brain received The Award for Excellence in Publishing in Medical Science (Assoc American Publishers, 1997) and The British Medical Association Illustrated Book Award (2016).

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"This atlas provides an excellent, detailed map of the entire spinal cord of both rat and mouse. The photomicrographs are outstanding, the labelling is clear and the illustrations should serve as outstanding examples of what high quality staining and immunocytochemistry should look like. This information has not been available in any atlas of the CNS before, and will be an extremely useful resource for all neuroscientist interested in this part of the nervous system and a 'must-have' for spinal cord labs." --Jacqueline C. Bresnahan, Professor, Department of Neurological Surgery, Brain and Spinal Injury Center, University of California at San Francisco, USA"The Spinal Cord is an authoritative and detailed account of the development, organization and function of the spinal cord. Written by a series of experts, the book contains enlightening chapters that cover the anatomy and the architecture of the spinal cord in a clear and logical fashion. Attention to special topics, such as spinal cord injury and micturition, is unprecedented and unusually informative. The comprehensive atlas, along with the diagrams and list of references, will be of considerable use to the students of the nervous system, as well as the most senior of investigators. It is an excellent volume!" --Moses V. Chao, Professor of Cell Biology, Physiology and Neuroscience and Psychiatry, Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, NYU School of Medicine, New York, USA

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