Clinical Molecular Medicine

Professor Kumar has considerable previous experience in writing and editing books and journals related to genetics and genomics. His books include Genomics and Clinical Medicine and Genomics and Health in the Developing World. He founded and leads the new open access journal Applied and Translational Genomics, published by Elsevier. He has published 40 articles in the journals literature. Professor Dhavendra Kumar is a Visiting Professor, Genomic Policy Unit, Faculty of Life Sciences and Education, The University of South Wales and Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom. He is one of the Consultants for the All Wales Medical Genetics Service and the lead Clinician for Clinical Cardiovascular Genetics. After qualifying in Medicine from the King George’s Medical College, University of Lucknow, India, he completed postgraduate training in Pediatrics with an MD. Since 1980 he has pursued a career in Medical Genetics in the UK. In 1990 he became a Diplomate of the American Board of Medical Genetics. He is a Fellow of the American College of Medical Genetics (FACMG) and as well as Royal Colleges of Physicians (FRCP-London and FRCP-Ireland) and Pediatrics and Child Health (FRCPCH-UK).In 2015, he was conferred with the higher degree of DSc by his Alma Mater, King George’s Medical University, Lucknow (UP, India) based on his life-time contributions and achievements to genetic and genomic applications in medicine and health.

• Part I. FUNDAMENTALS OF MOLECULAR MEDICINE1. The human genome and molecular medicine2. Cellular structure and molecular cell biology3. Molecular basis of clinical metabolomics4. Clinical applications of next-generation sequencingPart II. MOLECULAR MEDICINE IN CLINICAL PRACTICE5. Molecular basis of obesity disorders6. Molecular dysmorphology7. Disorders of sex development8. Molecular systems in cardiovascular developmental disorders9. Channelopathies in clinical medicine—cardiac arrhythmias10. Chronic heart failure11. Molecular pathophysiology of systemic hypertension12. Molecular basis of stroke13. Clinical molecular endocrinology14. Genetic disorders of lipoprotein metabolism15. Molecular medicine of diabetes mellitus16. Molecular genetic management of epilepsy17. The human leukocyte antigen system in human disease and transplantation medicine18. Disorders of abnormal hemoglobin19. Coagulation and bleeding disorders20. Molecular and genomic basis of bronchial asthma21. Molecular systems in inflammatory bowel disease22. Molecular biology of acute and chronic inflammation23. Molecular basis of susceptibility and protection from microbial infections24. Molecular mechanisms in cancer susceptibility—lessons from inherited cancers25. Clinical molecular nephrology—acute kidney injury and chronic kidney disease26. Molecular basis of chronic neurodegeneration27. Molecular basis of movement disorders28. Molecular pathology in neuropsychiatric disorders29. Targeted molecular therapy: the cancer paradigm30. Gene, genome, and molecular therapeutics31. Personalizing medicine with pharmacogenetics and pharmacogenomics32. Integrated genomic and molecular medicine