Pharmacoepigenetics

Dr. Ramón Cacabelos is Professor and Chairman of Genomic Medicine and President of the EuroEspes Biomedical Research Center, Corunna, Spain. He received his M.D. from Oviedo University, Oviedo, Spain; Ph.D. from Santiago University, Santiago de Compostela, Spain; and D.M.Sci. (Psychiatry) from Osaka University Medical School, Osaka, Japan. After a decade at the Department of Psychiatry in Osaka, he returned to Spain and focused his research activity on the genomics, epigenomics and pharmacogenomics of brain disorders, with special emphasis on neurodegenerative disorders (Alzheimer’s disease, Parkinson’s disease). He has published over 700 papers and 30 books and is Editor-in-Chief of the first World Guide for Drug Use and Pharmacogenomics and President of the World Association of Genomic Medicine.

• 1. The Epigenetic Machinery in the Life Cycle and Pharmacoepigenetics2. Pharmacoepigenetics: Basic Principles for Personalized Medicine3. Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport4. MicroRNA-Dependent Gene Regulation of the Human Cytochromes P4505. Pathoepigenetics: The Role of Epigenetic Biomarkers in Disease Pathogenesis6. Pharmacoepigenetic Processors: Epigenetic Drugs, Drug Resistance, Toxicoepigenetics, and Nutriepigenetics7. Pharmacoepigenetics of Novel Nucleoside DNA Methyltransferase Inhibitors8. Pharmacoepigenetics: Novel Mechanistic Insights in Drug Discovery and Development Targeting Chromatin-Modifying Enzymes9. Pharmacoepigenetics of EZH2 Inhibitors10. Regulators of Histone Acetylation: Bromodomain Inhibitors11. Bromodomain Inhibition and Its Application to Human Disease12. Epigenetic Drug Discovery for Cancer13. Pharmacoepigenetics of Histone Deacetylase Inhibitors in Cancer14. Pharmacoepigenetics of LSD1 Inhibitors in Cancer15. Pharmacoepigenetic Considerations for the Treatment of Breast Cancer16. Pharmacoepigenetics of Acute Myeloid Leukemia17. Therapeutic Potential of Pharmacoepigenetics in Cholangiocarcinoma18. Pharmacoepigenetics in Type 2 Diabetes Mellitus19. Pharmacoepigenetics of Immunological Disorders20. Pharmacoepigenetics of Rheumatic Disorders21. Pharmacoepigenetics of Systemic Lupus Erythematosus22. Epigenetics and Pharmacoepigenetics of Neurodevelopmental and Neuropsychiatric Disorders23. Pharmacoepigenetics and Toxicoepigenetics in Neurodevelopmental Disorders24. Pharmacoepigenetics of Autism Spectrum Disorder25. Pharmacoepigenetics of Antipsychotic Drugs26. Pharmacoepigenetics of Bipolar Disorder27. Pharmacoepigenetics of Major Depression28. Pharmacoepigenetics of Vertigo and Related Vestibular Syndromes29. Pharmacological Nicotinamide: Mechanisms Centered Around SIRT1 Activity30. Pharmacoepigenetics and Pharmacoepigenomics of Valproate in Neurodegenerative Disease31. Pharmacoepigenetics of Statins32. Pharmacoepigenetics of Memantine in Dementia33. Epigenetics in Doxorubicin Cardiotoxicity34. Pharmacoepigenetics of Brassica-Derived Compounds35. Pharmacoepigenetics of Chinese Herbal Components in Cancer36. Epigenetics of Aging and Age-Related Disorders37. Epigenetics of Aging and Cancer: A Comprehensive Look38. Epigenetics and Pharmacoepigenetics of Age-Related Neurodegenerative Disorders