Seyed Moayed Alavian is gastroenterologist and head of Tehran Hepatitis Center. He has authored/co-authored over 480 articles in local and international journals, including 300 articles indexed in ISI, 343 articles indexed in PubMed, and 55 articles indexed in Persian Journals and has more than 3800 citations to published articles as well as 65 books and booklets for physicians and patients. Seyed Mohammad Nabavi is a Biotechnologist and senior scientist in the Applied Biotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran. His research interests are focused on natural products. Till now, he has authored/co-authored over 250 publications in international journals indexed in ISI and has more than 7000 citations to published articles and also more than 10 books. Seyed Fazel Nabavi is a biotechnologist and Senior Scientist of Applied Biotechnology Research Center, Baqiyatallah University of Medical Science and a member of Iran’s National Elites Foundation. His research focused on the health-promotion effects of natural products. He is author/co-author of 170 publications in international journals, 45 communications at national and international congress and 4 chapters in book series. He is a referee of several international journals. He is also in the top 1% top scientists in the world in the fields of Agricultural Sciences and Pharmacology & Toxicology according to Essential Science Indicator from Thompson Reuters ISI. Ana Sanches Silva is a researcher at the National Institute of Agrarian and Veterinary Research (INIAV, IP). She obtained a degree in Pharmacy from the University of Coimbra, Portugal, and received her European Ph.D. in Pharmacy from the University of Santiago de Compostela, Spain, with honors. In addition, she was awarded with the prize for best doctorate student. Ana Sanches-Silva has a remarkable track record (over 100 scientific contributions in peer-reviewed journals or book chapters). She has more than 300 communications in national and international conferences. Her research interests are focused on the evaluation of safety and composition of food and food packaging. Moreover, her special interest is the study of food bioactive compounds and dietary supplements, and development of analytical methodologies for the analysis of bioactive compounds in food.

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• 1. IntroductionPart 1: Hepatoprotective activity of natural compounds and plant extracts in liver diseases2. Hepatitis B3. Hepatitis C4. Alcoholic fatty liver disease5. Non-alcoholic fatty liver disease (NAFLD)6. Liver cancer7. Chronic liver diseases (steatosis, fibrosis, primary sclerosing cholangitis, biliary cirrhosis)8. Drug-induced hepatotoxicityPart 2: Influence of nutrients, plant extracts and natural compounds in liver diseases9. Influence of Omega-3 fatty acids and Monounsaturated fats in liver diseases10. Influence of vitamins (E, C, niacin and D) in liver diseases11. Influence of other nutrients (e.g. l-arginine, taurine and choline) in liver diseases12. Antioxidants with hepatoprotective activity13. Plant extracts with putative hepatoprotective activity14. Plant extracts with putative hepatotoxicity activity15. Other compounds with hepatotoxicity

Seyed Moayed Alavian is gastroenterologist and head of Tehran Hepatitis Center. He has authored/co-authored over 480 articles in local and international journals, including 300 articles indexed in ISI, 343 articles indexed in PubMed, and 55 articles indexed in Persian Journals and has more than 3800 citations to published articles as well as 65 books and booklets for physicians and patients. Seyed Mohammad Nabavi is a Biotechnologist and senior scientist in the Applied Biotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran. His research interests are focused on natural products. Till now, he has authored/co-authored over 250 publications in international journals indexed in ISI and has more than 7000 citations to published articles and also more than 10 books. Seyed Fazel Nabavi is a biotechnologist and Senior Scientist of Applied Biotechnology Research Center, Baqiyatallah University of Medical Science and a member of Iran’s National Elites Foundation. His research focused on the health-promotion effects of natural products. He is author/co-author of 170 publications in international journals, 45 communications at national and international congress and 4 chapters in book series. He is a referee of several international journals. He is also in the top 1% top scientists in the world in the fields of Agricultural Sciences and Pharmacology & Toxicology according to Essential Science Indicator from Thompson Reuters ISI. Ana Sanches Silva is a researcher at the National Institute of Agrarian and Veterinary Research (INIAV, IP). She obtained a degree in Pharmacy from the University of Coimbra, Portugal, and received her European Ph.D. in Pharmacy from the University of Santiago de Compostela, Spain, with honors. In addition, she was awarded with the prize for best doctorate student. Ana Sanches-Silva has a remarkable track record (over 100 scientific contributions in peer-reviewed journals or book chapters). She has more than 300 communications in national and international conferences. Her research interests are focused on the evaluation of safety and composition of food and food packaging. Moreover, her special interest is the study of food bioactive compounds and dietary supplements, and development of analytical methodologies for the analysis of bioactive compounds in food.

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• 1. IntroductionPart 1: Hepatoprotective activity of natural compounds and plant extracts in liver diseases2. Hepatitis B3. Hepatitis C4. Alcoholic fatty liver disease5. Non-alcoholic fatty liver disease (NAFLD)6. Liver cancer7. Chronic liver diseases (steatosis, fibrosis, primary sclerosing cholangitis, biliary cirrhosis)8. Drug-induced hepatotoxicityPart 2: Influence of nutrients, plant extracts and natural compounds in liver diseases9. Influence of Omega-3 fatty acids and Monounsaturated fats in liver diseases10. Influence of vitamins (E, C, niacin and D) in liver diseases11. Influence of other nutrients (e.g. l-arginine, taurine and choline) in liver diseases12. Antioxidants with hepatoprotective activity13. Plant extracts with putative hepatoprotective activity14. Plant extracts with putative hepatotoxicity activity15. Other compounds with hepatotoxicity

Seyed Moayed Alavian is gastroenterologist and head of Tehran Hepatitis Center. He has authored/co-authored over 480 articles in local and international journals, including 300 articles indexed in ISI, 343 articles indexed in PubMed, and 55 articles indexed in Persian Journals and has more than 3800 citations to published articles as well as 65 books and booklets for physicians and patients. Seyed Mohammad Nabavi is a Biotechnologist and senior scientist in the Applied Biotechnology Research Centre, Baqiyatallah University of Medical Sciences, Tehran, Iran. His research interests are focused on natural products. Till now, he has authored/co-authored over 250 publications in international journals indexed in ISI and has more than 7000 citations to published articles and also more than 10 books. Seyed Fazel Nabavi is a biotechnologist and Senior Scientist of Applied Biotechnology Research Center, Baqiyatallah University of Medical Science and a member of Iran’s National Elites Foundation. His research focused on the health-promotion effects of natural products. He is author/co-author of 170 publications in international journals, 45 communications at national and international congress and 4 chapters in book series. He is a referee of several international journals. He is also in the top 1% top scientists in the world in the fields of Agricultural Sciences and Pharmacology & Toxicology according to Essential Science Indicator from Thompson Reuters ISI. Ana Sanches Silva is a researcher at the National Institute of Agrarian and Veterinary Research (INIAV, IP). She obtained a degree in Pharmacy from the University of Coimbra, Portugal, and received her European Ph.D. in Pharmacy from the University of Santiago de Compostela, Spain, with honors. In addition, she was awarded with the prize for best doctorate student. Ana Sanches-Silva has a remarkable track record (over 100 scientific contributions in peer-reviewed journals or book chapters). She has more than 300 communications in national and international conferences. Her research interests are focused on the evaluation of safety and composition of food and food packaging. Moreover, her special interest is the study of food bioactive compounds and dietary supplements, and development of analytical methodologies for the analysis of bioactive compounds in food.

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• 1. IntroductionPart 1: Hepatoprotective activity of natural compounds and plant extracts in liver diseases2. Hepatitis B3. Hepatitis C4. Alcoholic fatty liver disease5. Non-alcoholic fatty liver disease (NAFLD)6. Liver cancer7. Chronic liver diseases (steatosis, fibrosis, primary sclerosing cholangitis, biliary cirrhosis)8. Drug-induced hepatotoxicityPart 2: Influence of nutrients, plant extracts and natural compounds in liver diseases9. Influence of Omega-3 fatty acids and Monounsaturated fats in liver diseases10. Influence of vitamins (E, C, niacin and D) in liver diseases11. Influence of other nutrients (e.g. l-arginine, taurine and choline) in liver diseases12. Antioxidants with hepatoprotective activity13. Plant extracts with putative hepatoprotective activity14. Plant extracts with putative hepatotoxicity activity15. Other compounds with hepatotoxicity