Dr. António Salgado is a PrincipaI Investigator at the Life and Health Sciences Research Institute (ICVS) and an Adjunct Associate Professor in the School of Medicine, University of Minho. His research interests are focused on the development of innovative therapies for CNS repair, namely on Spinal Cord Injury and Parkinson’s Disease. His main areas of research are: 1) Development of ECM like hydrogels for the transplantation of Mesenchymal Stem Cells into the injured CNS; 2) Role of the secretome of MSCs in neuroprotection and repair, particularly the establishment of novel therapies based on the sole use of MSCs secretome.. Presently he is the coordinator of the Portuguese Network for Spinal Cord Injury Research and director of the Spinal Cord Injury Initiative @ ICVS (SCICVS). He serves as an Associate Editor for Biomed Research International, Biochimie, BMC Neuroscience and Stem Cells International. He has received several distinctions for his work including the Gulbenkian Award on Cutting Edge Research in Life Sciences, and the Prize Melo e Castro for Spinal Cord Injury Research, awarded by Santa Casa de Misericordia de Lisboa (2013 and 2017).

"The book's subject matter helps give readers context surrounding upcoming advances in the field of CNS regenerative medicine. The book will be useful to practitioners faced with answering difficult questions of those who have experienced a CNS injury, such as what is in the pipeline and/or what may be helpful in the future. The book also makes research concepts more accessible to students and residents to foster further research in these areas." --Doody Reviews

• 1. Insights on Nervous System Biology and Anatomy2. Introduction to Neurodegenerative Diseases3. Introduction to Trauma in CNS4. Impact of Neuro-inflammation in Injury and Disease in the CNS5. Current Clinical Approaches in Neurodegenerative Diseases6. Neuroprotection in the Injured Spinal Cord7. Immunomodelatory Approaches for Tackling Neuro-Inflammation8. Role of Fetal and Adult Tissues in CNS Regenerative Medicine9. Adult Stem Cells' Therapeutic Potential for Injured CNS10. iPSCs: An Essential Toolkit for Repair and Regeneration of the CNS?11. Biomaterial-Based Systems as Biomimetic Agents in the Repair of the CNS12. Tissue Engineering and Regenerative Medicine in CNS Repair13. New Trends in Drug Delivery in CNS Regeneration14. Gene Therapy Approaches in CNS Regenerative Medicine15. Gene Editing and CNS Regeneration16. Molecular Therapies in Neurodegeneration and Injury17. Deep Brain Stimulation and Parkinson's Disease18. Brain-Spinal Cord Interfaces19. Electroceuticals20. Secretome of Cells and Its Role in Neuroregeneration21. 3D Organoids and Bioreactors22. Microfluidics and Lab-on-a-Chip23. Translational Research: From Proof of Concept to Clinical Trials24. Advanced Therapies Medicinal Products25. Animal Models of CNS Disorders26. Bioethics in Translation Research and Clinical Trials

Dr. António Salgado is a PrincipaI Investigator at the Life and Health Sciences Research Institute (ICVS) and an Adjunct Associate Professor in the School of Medicine, University of Minho. His research interests are focused on the development of innovative therapies for CNS repair, namely on Spinal Cord Injury and Parkinson’s Disease. His main areas of research are: 1) Development of ECM like hydrogels for the transplantation of Mesenchymal Stem Cells into the injured CNS; 2) Role of the secretome of MSCs in neuroprotection and repair, particularly the establishment of novel therapies based on the sole use of MSCs secretome.. Presently he is the coordinator of the Portuguese Network for Spinal Cord Injury Research and director of the Spinal Cord Injury Initiative @ ICVS (SCICVS). He serves as an Associate Editor for Biomed Research International, Biochimie, BMC Neuroscience and Stem Cells International. He has received several distinctions for his work including the Gulbenkian Award on Cutting Edge Research in Life Sciences, and the Prize Melo e Castro for Spinal Cord Injury Research, awarded by Santa Casa de Misericordia de Lisboa (2013 and 2017).

"The book's subject matter helps give readers context surrounding upcoming advances in the field of CNS regenerative medicine. The book will be useful to practitioners faced with answering difficult questions of those who have experienced a CNS injury, such as what is in the pipeline and/or what may be helpful in the future. The book also makes research concepts more accessible to students and residents to foster further research in these areas." --Doody Reviews

• 1. Insights on Nervous System Biology and Anatomy2. Introduction to Neurodegenerative Diseases3. Introduction to Trauma in CNS4. Impact of Neuro-inflammation in Injury and Disease in the CNS5. Current Clinical Approaches in Neurodegenerative Diseases6. Neuroprotection in the Injured Spinal Cord7. Immunomodelatory Approaches for Tackling Neuro-Inflammation8. Role of Fetal and Adult Tissues in CNS Regenerative Medicine9. Adult Stem Cells' Therapeutic Potential for Injured CNS10. iPSCs: An Essential Toolkit for Repair and Regeneration of the CNS?11. Biomaterial-Based Systems as Biomimetic Agents in the Repair of the CNS12. Tissue Engineering and Regenerative Medicine in CNS Repair13. New Trends in Drug Delivery in CNS Regeneration14. Gene Therapy Approaches in CNS Regenerative Medicine15. Gene Editing and CNS Regeneration16. Molecular Therapies in Neurodegeneration and Injury17. Deep Brain Stimulation and Parkinson's Disease18. Brain-Spinal Cord Interfaces19. Electroceuticals20. Secretome of Cells and Its Role in Neuroregeneration21. 3D Organoids and Bioreactors22. Microfluidics and Lab-on-a-Chip23. Translational Research: From Proof of Concept to Clinical Trials24. Advanced Therapies Medicinal Products25. Animal Models of CNS Disorders26. Bioethics in Translation Research and Clinical Trials

Dr. António Salgado is a PrincipaI Investigator at the Life and Health Sciences Research Institute (ICVS) and an Adjunct Associate Professor in the School of Medicine, University of Minho. His research interests are focused on the development of innovative therapies for CNS repair, namely on Spinal Cord Injury and Parkinson’s Disease. His main areas of research are: 1) Development of ECM like hydrogels for the transplantation of Mesenchymal Stem Cells into the injured CNS; 2) Role of the secretome of MSCs in neuroprotection and repair, particularly the establishment of novel therapies based on the sole use of MSCs secretome.. Presently he is the coordinator of the Portuguese Network for Spinal Cord Injury Research and director of the Spinal Cord Injury Initiative @ ICVS (SCICVS). He serves as an Associate Editor for Biomed Research International, Biochimie, BMC Neuroscience and Stem Cells International. He has received several distinctions for his work including the Gulbenkian Award on Cutting Edge Research in Life Sciences, and the Prize Melo e Castro for Spinal Cord Injury Research, awarded by Santa Casa de Misericordia de Lisboa (2013 and 2017).

"The book's subject matter helps give readers context surrounding upcoming advances in the field of CNS regenerative medicine. The book will be useful to practitioners faced with answering difficult questions of those who have experienced a CNS injury, such as what is in the pipeline and/or what may be helpful in the future. The book also makes research concepts more accessible to students and residents to foster further research in these areas." --Doody Reviews

• 1. Insights on Nervous System Biology and Anatomy2. Introduction to Neurodegenerative Diseases3. Introduction to Trauma in CNS4. Impact of Neuro-inflammation in Injury and Disease in the CNS5. Current Clinical Approaches in Neurodegenerative Diseases6. Neuroprotection in the Injured Spinal Cord7. Immunomodelatory Approaches for Tackling Neuro-Inflammation8. Role of Fetal and Adult Tissues in CNS Regenerative Medicine9. Adult Stem Cells' Therapeutic Potential for Injured CNS10. iPSCs: An Essential Toolkit for Repair and Regeneration of the CNS?11. Biomaterial-Based Systems as Biomimetic Agents in the Repair of the CNS12. Tissue Engineering and Regenerative Medicine in CNS Repair13. New Trends in Drug Delivery in CNS Regeneration14. Gene Therapy Approaches in CNS Regenerative Medicine15. Gene Editing and CNS Regeneration16. Molecular Therapies in Neurodegeneration and Injury17. Deep Brain Stimulation and Parkinson's Disease18. Brain-Spinal Cord Interfaces19. Electroceuticals20. Secretome of Cells and Its Role in Neuroregeneration21. 3D Organoids and Bioreactors22. Microfluidics and Lab-on-a-Chip23. Translational Research: From Proof of Concept to Clinical Trials24. Advanced Therapies Medicinal Products25. Animal Models of CNS Disorders26. Bioethics in Translation Research and Clinical Trials