Aging

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books. Vinood B. Patel, BSc, PhD, FRSC, is currently Professor in Clinical Biochemistry at the University of Westminster. In 2014 Dr Patel was elected as a Fellow to The Royal Society of Chemistry. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King’s College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School, NC, USA studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Research is being undertaken to study the role of nutrients, antioxidants, phytochemicals, iron, alcohol and fatty acids in the pathophysiology of liver disease. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding mitochondrial oxidative stress in neurological disorders and iron dysregulation in diabetes. Dr Patel is a nationally and internationally recognized researcher and has several edited biomedical books related to the use or investigation of active agents or components. These books include The Handbook of Nutrition, Diet, and Epigenetics, Branched Chain Amino Acids in Clinical Nutrition, Cancer: Oxidative Stress and Dietary Antioxidants, Toxicology: Oxidative Stress and Dietary Antioxidants, Molecular Nutrition: Vitamins, The Neuroscience of Pain, Cognitive Behavioural Therapy. He is Editor of the ten-volume series Biomarkers in Disease: Methods, Discoveries and Applications.

• PrefaceI. Oxidative stress and aging1. Oxidative stress and mir-200cAlessandra Magenta, Maria Cristina Florio, Marco D’Agostino, Sara Sileno2. Caloric restriction, reactive oxygen species, and longevityMiyuki Kobara, Hiroe Toba, Tetsuo Nakata3. Cardiovascular disease in aging and the role of oxidative stressLucie Orliaguet, Vinood B. Patel, Victor R. Preedy, Fawaz Alzaid4. Aging, oxidative stress, mitochondrial dysfunction, and the liverJanice G. Lozada-Delgado, Carlos A. Torres-Ramos, Sylvette Ayala-Peña5. Culprit effect of oxidative stress in the development of parkinson’s disease: a conundrum of senescenceRahul Saxena, Gladys Rai6. Linking bone cells, aging, and oxidative stress: osteoblasts, osteoclasts, osteocytes, and bone marrow cellsJuan A. Ardura, Luis Álvarez-Carrión, Arancha R. Gortázar, Verónica Alonso7. Oxidative stress, senescence and mediterranean diet effects on osteoarthritisSergio Ammendola, Anna Scotto D’Abusco8. Arthritis as a disease of aging and changes in antioxidant statusRahul Saxena, Jyoti Batra9. Oxidative stress and sarcopeniaFrancesco Bellanti, Aurelio Lo Buglio, Gianluigi Vendemiale10. Oxidative stress and hypertension in old age: the role of physical exerciseClodoaldo Antônio De Sá, Vanessa Corralo, Francielle Garghetti Battiston, Maria Isabel Gonc¸ Alves Da Silva11. Linking senescence, apoptosis, and oxidative stress in fertilityMathias Abiodun Emokpae, Osaretin Godwin Igharo12. Antioxidant capacity and menopausal symptomsGity Sotoudeh, Maryam AbshiriniII. Antioxidants and aging13. Reference dietary requirements of antioxidant vitamins in the older adultsMina Yamazaki Price, Victor R. Preedy14. Oxidative stress and antioxidants in elderly womenBrunna Cristina Bremer Boaventura, Patricia Faria Di Pietro, Francieli Cembranel15. Caffeine and its analogs, antioxidants, and applicationsBeata Jasiewicz, Arleta Sierakowska16. Coenzyme q10 as an antioxidant in the elderlyElena M. Yubero-Serrano, Francisco M. Gutierrez-Mariscal, Antonio Garcia-Rios, Javier Delgado-Lista, Pablo Pérez-Martinez, Antonio Camargo, Francisco Perez-Jimenez, Jose Lopez-Miranda17. The role of coenzyme q10 in the protection of bone health during agingJosé L. Quiles, José M. Romero-Márquez, Mariá D. Navarro-Hortal, Maurizio Battino, Alfonso Varela-López18. Coenzyme q10 supplementation in agingGuillermo López-Lluch, Plácido Navas19. Crocus sativus l. (saffron) extract antioxidant potential and use in agingSaeed Samarghandian, Tahereh Farkhondeh, Tayebeh Zeinali20. Pharmacological profile of γ-oryzanol: its antioxidant mechanisms and its effects in age-related diseasesWiramon Rungratanawanich, Giulia Abate, Daniela Uberti21. Herbs including shell ginger, antioxidant profiles, aging, and longevity in okinawa, japan: a critical analysis of current conceptsRolf Teschke, Tran Dang Xuan22. Lycopene as an antioxidant in the prevention and treatment of postmenopausal osteoporosisL.G. Rao, E.S. Mackinnon, A.V. Rao23. Medicinal plants, antioxidant potential, and applications to agingWaseem Hassan, Mehreen Zafar, Jean Paul Kamdem24. Antioxidant and anti-inflammatory role of melatonin in alzheimer’s neurodegenerationSergio A. Rosales-Corral, Russel J. Reiter, Xiaoyan Liu25. Murici (byrsonima crassifolia (l.) Kunth): antioxidant effects and application to agingMariana Séfora Bezerra Sousa Diego De Souza Buarque26. Natural products in aging skinMahendran Sekar27. Antioxidant properties and applications of ophiopogon japonicus root for age-related diseaseYumi Kitahiro, Makio Shibano28. Passion fruit seed: its antioxidative extracts and potency in protection of skin agingNattaya Lourith, Mayuree Kanlayavattanakul29. Phaseolus vulgaris l. As a functional food for aging protectionEunice Santos, Guilhermina Marques, Teresa Lino-Neto30. Quercetin and resveratrol, aging and kidneyMina Hemmati, Maryam Moossavi31. Rambutan fruits extract in aging skinMahendran Sekar32. Resveratrol, aging, and fatigueLuana Toniolo, Emiliana Giacomello33. Resveratrol, sirt1, oxidative stress, and brain agingFiorella Sarubbo, Silvia Tejada, Susana Esteban, Manuel Jimenez-Garciá, David Moranta34. Antioxidants, vegetarian diets, and age-related diseaseAndrew C. Bulmer, Shailendra Anoopkumar-Dukie, Iris F.F. Benzie35. Protective effect of vitamin d on oxidative stress in elderly peopleBrunna Cristina Bremer Boaventura, Francieli Cembranel36. Zinc, oxidative stress in the elderly, and implication for inflammationAnanda S. Prasad, Bin Bao37. Oxidative stress and the senescence acceleration in senescence-accelerated mouse p10 (samp10)Takeshi Saito, Masaaki Kurasaki38. Recommended resources on aging: oxidative stress and dietary antioxidantsRajkumar Rajendram, Vinood B. Patel, Victor R. PreedyIndex