Nanoparticle Therapeutics

Production Technologies, Types of Nanoparticles, and Regulatory Aspects

AvPrashant Kesharwani,Kamalinder K. Singh

Häftad, Engelska, 2021

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Beskrivning

Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states.

This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful.

Brings together the novel applications of nanotechnology in biological fields
Explores perspectives on technologies through highly organized tables, illustrative figures and flow charts
Addresses key multidisciplinary challenges faced by nanotechnologists to foster collaboration among biologists, chemists, physicists, engineers and clinicians

Produktinformation

Utgivningsdatum:2021-11-11
Mått:191 x 235 x undefined mm
Vikt:450 g
Format:Häftad
Språk:Engelska
Antal sidor:672
Förlag:Elsevier Science
ISBN:9780128207574

Utforska kategorier

Farmakologi inom Medicin
Biokemisk teknik inom Naturvetenskap och teknik
Biomedicinsk teknik inom Medicin

Mer om författaren

Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya University, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience across various countries. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has published many articles in well-reputed journals and a large number of books. He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award, and “SERB-Ramanujan Fellowship Award. He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community. Prof Kamalinder K Singh is Professor of Pharmaceutical Technology & Drug Delivery and Research Lead at the School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, United Kingdom and heads the Nanomedicine and Innovative technologies research group within the Faculty of Clinical and Biomedical Sciences and is Healthcare Lead for UCLan Centre of Smarts Materials. With more than 35 years’ experience in academia, Prof Singh has contributed significantly to the field of pharmaceutical technology, drug delivery and nanomedicine through authorship of over 80 research articles, 18 patents, 12 book chapters and 60 monographs. Her pioneering research has led to development of many biocompatible nanoparticle-based platform technologies exploiting to deliver drugs across various biological barriers with application to human health and diseases. Prof Singh serves on International Steering Committee for ‘Handbook of Pharmaceutical Excipients’, joint publication by AAPS, Pharmaceutical Press, and Royal Pharmaceutical Society, Great Britain. She has provided leadership to 35 major funded research projects and is currently managing several research projects funded by National Institute of Health, Academy of Medical Sciences, British Council and UK Foreign Commonwealth and Development Office. She has supervised 30 ECRs and delivered more than 70 keynotes and invited talks at prestigious forums around the globe.

Recensioner i media

"This book is comprehensive, up to date, and well organized and illustrated. It covers all aspects and technologies relevant to nanoparticle therapeutic use and is expected to become a reference in the field of nanotechnology." --DOODY'S BOOK REVIEW SERVICE UPDATE

Innehållsförteckning

Part 1: Synthesis and characterization of NP for drug delivery1. Nanoparticles: Recent state-of-art and prospective challenges2. Fabrication, process technologies and challenges in development of nanoparticles3. In vitro and physicochemical characterization of nanoparticles4. Surface-engineering of nanoparticles for imparting multifuntionality5. Biofate and cellular interactions of nanoparticles6. Pharmacokinetics and in vivo evaluation of nanoparticlesPart 2: Application of Nanoparticles in Drug Delivery7. Biodegradable polymeric nanoparticles for sustained drug delivery8. Lipidic nanoparticles with improved biopharmaceutical attributes9. Protein-based nanoparticles for drug delivery10. Gold and silver nanoparticles for drug delivery11. Mesoporous silica and silicates nanoparticles for drug delivery12. Targeted nanosuspensions for improved therapeutics13. SPIONS as therapeutic and diagnostic agents14. Bio-inspired nanoparticles/exosomes vesicles as drug delivery vehiclesPart 3: Environmental and Regulatory Aspects14. Regulatory pathways and federal perspectives on nanoparticles15. Environmental hazards associated with nanoparticles16. Biological toxicity of nanoparticles