Abdulrahman M. El-Sayed, MD, DPhil, is a public health physician and epidemiologist. He serves the City of Detroit as the Executive Director of the Detroit Health Department and Health Officer. Under his leadership, the Detroit Health Department has emerged as a state and national leader in promoting healthy air quality, lead elimination, and public health innovation. Dr. El-Sayed's research explores urban health policy, the social determinants of health, and health inequalities. Previously, he was a professor in the Department of Epidemiology at Columbia University.Sandro Galea, MD, DrPH, is a physician and an epidemiologist interested in the social production of health of urban populations. His work explores innovative cells-to-society approaches to population health questions. He is interested in advancing a consequentialist approach to population health scholarship. He currently serves as Robert A. Knox Professor and Dean of the School of Public Health at Boston University. He is a past president of the Society for Epidemiologic Research, and an elected member of the National Academy of Medicine.Together they have been engaged in systems science scholarship and education for more than 15 years.

• 1.Introduction Abdulrahman M. El-Sayed SECTION 1: Simplicity, complexity and population health 2. Reductionism at the dawn of population healthKristin Heitman 3. Wrong answers: when simple interpretations create complex problemsDavid S. Fink, Katherine M. Keyes 4. Complexity: the evolution towards 21st century scienceAnton Palma, David W. Lounsbury 5. Systems thinking in population health research and policyStephen Mooney SECTION 2: Methods in systems population health 6. Generation of systems maps: mapping complex systems of population healthHelen de Pinho 7. Systems dynamics modelsEric Lofgren 8. Agent-based modelingBrandon Marshall 9. MicrosimulationSanjay Basu 10. Social network analysis: the ubiquity of social networks and their importance for population healthDouglas A. Luke, Amar Dhand, Bobbi J. Carothers SECTION 3: Systems science towards a consequential population health 11. Machine learningJames H. Faghmous 12. Systems science and the social determinants of population healthDavid S. Fink, Katherine M. Keyes, Magdalena Cerdá 13. Systems approaches to understanding how the environment influences population health and population health interventionsMelissa Tracy 14. Systems of behavior and population healthMark Orr, Kathryn Ziemer, Daniel Chen 15. Systems under your skinKarina Standahl Olsen, Hege Bøvelstad, Eiliv Lund 16. Frontiers in health modelingNathaniel Osgood 17. Systems science and population healthAbdulrahman M. El-Sayed, Sandro Galea

Abdulrahman M. El-Sayed, MD, DPhil, is a public health physician and epidemiologist. He serves the City of Detroit as the Executive Director of the Detroit Health Department and Health Officer. Under his leadership, the Detroit Health Department has emerged as a state and national leader in promoting healthy air quality, lead elimination, and public health innovation. Dr. El-Sayed's research explores urban health policy, the social determinants of health, and health inequalities. Previously, he was a professor in the Department of Epidemiology at Columbia University.Sandro Galea, MD, DrPH, is a physician and an epidemiologist interested in the social production of health of urban populations. His work explores innovative cells-to-society approaches to population health questions. He is interested in advancing a consequentialist approach to population health scholarship. He currently serves as Robert A. Knox Professor and Dean of the School of Public Health at Boston University. He is a past president of the Society for Epidemiologic Research, and an elected member of the National Academy of Medicine.Together they have been engaged in systems science scholarship and education for more than 15 years.

• 1.Introduction Abdulrahman M. El-Sayed SECTION 1: Simplicity, complexity and population health 2. Reductionism at the dawn of population healthKristin Heitman 3. Wrong answers: when simple interpretations create complex problemsDavid S. Fink, Katherine M. Keyes 4. Complexity: the evolution towards 21st century scienceAnton Palma, David W. Lounsbury 5. Systems thinking in population health research and policyStephen Mooney SECTION 2: Methods in systems population health 6. Generation of systems maps: mapping complex systems of population healthHelen de Pinho 7. Systems dynamics modelsEric Lofgren 8. Agent-based modelingBrandon Marshall 9. MicrosimulationSanjay Basu 10. Social network analysis: the ubiquity of social networks and their importance for population healthDouglas A. Luke, Amar Dhand, Bobbi J. Carothers SECTION 3: Systems science towards a consequential population health 11. Machine learningJames H. Faghmous 12. Systems science and the social determinants of population healthDavid S. Fink, Katherine M. Keyes, Magdalena Cerdá 13. Systems approaches to understanding how the environment influences population health and population health interventionsMelissa Tracy 14. Systems of behavior and population healthMark Orr, Kathryn Ziemer, Daniel Chen 15. Systems under your skinKarina Standahl Olsen, Hege Bøvelstad, Eiliv Lund 16. Frontiers in health modelingNathaniel Osgood 17. Systems science and population healthAbdulrahman M. El-Sayed, Sandro Galea

Abdulrahman M. El-Sayed, MD, DPhil, is a public health physician and epidemiologist. He serves the City of Detroit as the Executive Director of the Detroit Health Department and Health Officer. Under his leadership, the Detroit Health Department has emerged as a state and national leader in promoting healthy air quality, lead elimination, and public health innovation. Dr. El-Sayed's research explores urban health policy, the social determinants of health, and health inequalities. Previously, he was a professor in the Department of Epidemiology at Columbia University.Sandro Galea, MD, DrPH, is a physician and an epidemiologist interested in the social production of health of urban populations. His work explores innovative cells-to-society approaches to population health questions. He is interested in advancing a consequentialist approach to population health scholarship. He currently serves as Robert A. Knox Professor and Dean of the School of Public Health at Boston University. He is a past president of the Society for Epidemiologic Research, and an elected member of the National Academy of Medicine.Together they have been engaged in systems science scholarship and education for more than 15 years.

• 1.Introduction Abdulrahman M. El-Sayed SECTION 1: Simplicity, complexity and population health 2. Reductionism at the dawn of population healthKristin Heitman 3. Wrong answers: when simple interpretations create complex problemsDavid S. Fink, Katherine M. Keyes 4. Complexity: the evolution towards 21st century scienceAnton Palma, David W. Lounsbury 5. Systems thinking in population health research and policyStephen Mooney SECTION 2: Methods in systems population health 6. Generation of systems maps: mapping complex systems of population healthHelen de Pinho 7. Systems dynamics modelsEric Lofgren 8. Agent-based modelingBrandon Marshall 9. MicrosimulationSanjay Basu 10. Social network analysis: the ubiquity of social networks and their importance for population healthDouglas A. Luke, Amar Dhand, Bobbi J. Carothers SECTION 3: Systems science towards a consequential population health 11. Machine learningJames H. Faghmous 12. Systems science and the social determinants of population healthDavid S. Fink, Katherine M. Keyes, Magdalena Cerdá 13. Systems approaches to understanding how the environment influences population health and population health interventionsMelissa Tracy 14. Systems of behavior and population healthMark Orr, Kathryn Ziemer, Daniel Chen 15. Systems under your skinKarina Standahl Olsen, Hege Bøvelstad, Eiliv Lund 16. Frontiers in health modelingNathaniel Osgood 17. Systems science and population healthAbdulrahman M. El-Sayed, Sandro Galea