Theory Change in Science

"This will be a welcome and useful book for all those interested in the history and philosophy of genetics. Although primarily a philosopher of science, Lindley Darden has crafted a unique and challenging fusion of an historical with a philosophical approach. Refreshingly, she is not concerned with what ought to have been done, but what was done. Darden's book has a number of strong points: perhaps the most important of which is its attempt to show theunderlying conceptual changes through which Mendelian theory underwent after 1900 in terms of several general strategies advocated by its proponents." --Mendel Newsletter"Darden traces the mutual influences of theory and experiment very well, giving due weight to alternative models that were later deemed inadequate. Darden is developing a rigorous procedure for understanding how theories are formulated, modified, accepted, and rejected." --The Quarterly Review of Biology"A welcome and useful book for all those interested in the history and philosophy of genetics. . . . a unique and challenging fusion of a historical approach and a philosophical one. Darden has a good historical sense and presents to the reader questions and problems as they might have been viewed by investigators at the time, and not as we see them from today's perspective. . . . meticulous in illustrating the various strategies she describes by specificexamples. . . . a refreshing approach." --Bulletin of the History of Medicine"The most successful attempt I know to 'remove some of the mystery from the development of new scientific ideas.' Darden develops a theoretical model of scientific change from a detailed historical reconstruction. The merit of the book is to show the richness and the variability of the territory and to discuss in detail the adequacies and inadequacies of the proposed map. For its clarity, rational construction, and readability, this book should be used as atextbook. . . . will be a useful tool and a source of many insights for both historians of biology and philosophers of science. . . . has a great didactic value." --ISIS"[Darden's] book demonstrates the enormous value that a careful study of the history of science has for philosophers of science. . . . There is little to find fault with in Darden's book. The historical treatment of the development of Mendelian theory is thorough. . . . It is impossible to do justice to the scope and richness of Darden's book in a short review; suffice it to say that her book exemplifies a successful strategy for bringing together the historyof science and the philosophy of science."--Bradley E. Wilson, University of Pittsburgh"This will be a welcome and useful book for all those interested in the history and philosophy of genetics. Although primarily a philosopher of science, Lindley Darden has crafted a unique and challenging fusion of an historical with a philosophical approach. Refreshingly, she is not concerned with what ought to have been done, but what was done. Darden's book has a number of strong points: perhaps the most important of which is its attempt to show theunderlying conceptual changes through which Mendelian theory underwent after 1900 in terms of several general strategies advocated by its proponents." --Mendel Newsletter"Darden traces the mutual influences of theory and experiment very well, giving due weight to alternative models that were later deemed inadequate. Darden is developing a rigorous procedure for understanding how theories are formulated, modified, accepted, and rejected." --The Quarterly Review of Biology"A welcome and useful book for all those interested in the history and philosophy of genetics. . . . a unique and challenging fusion of a historical approach and a philosophical one. Darden has a good historical sense and presents to the reader questions and problems as they might have been viewed by investigators at the time, and not as we see them from today's perspective. . . . meticulous in illustrating the various strategies she describes by specificexamples. . . . a refreshing approach." --Bulletin of the History of Medicine"The most successful attempt I know to 'remove some of the mystery from the development of new scientific ideas.' Darden develops a theoretical model of scientific change from a detailed historical reconstruction. The merit of the book is to show the richness and the variability of the territory and to discuss in detail the adequacies and inadequacies of the proposed map. For its clarity, rational construction, and readability, this book should be used as atextbook. . . . will be a useful tool and a source of many insights for both historians of biology and philosophers of science. . . . has a great didactic value." --ISIS"[Darden's] book demonstrates the enormous value that a careful study of the history of science has for philosophers of science. . . . There is little to find fault with in Darden's book. The historical treatment of the development of Mendelian theory is thorough. . . . It is impossible to do justice to the scope and richness of Darden's book in a short review; suffice it to say that her book exemplifies a successful strategy for bringing together the historyof science and the philosophy of science."--Bradley E. Wilson, University of Pittsburgh

• Introduction; Philosophical preliminaries; The problem of heredity; Historical introduction; Mendelism, 1900-1903; Unit-characters, pairs, and dominance; Boveri-Sutton chromosome theory; Tests of segregation; Reduplication, linkage, and Mendel's second law; The chromosome theory and mutation; Unit-characters to factors to genes; Exemplars, diagrams, and diagnosis; Genetics and other fields; Summary of strategies for theory change; Implications for further work.